A5083213879- Colorectal Cancer Surgical Treatments
- Clinical practice guidelines implementation
- Colorectal Cancer Screening and Detection
- Cardiac, Anesthesia and Surgical Outcomes
- Colorectal and Anal Carcinomas
- Colorectal Cancer Treatments and Studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Pancreatic and Hepatic Oncology Research
- Multiple and Secondary Primary Cancers
- Global Healthcare and Medical Tourism
- Cancer Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Global Cancer Incidence and Screening
- Breast Cancer Treatment Studies
- Hemodynamic Monitoring and Therapy
- Aortic aneurysm repair treatments
- Venous Thromboembolism Diagnosis and Management
- Enhanced Recovery After Surgery
- Nutrition and Health in Aging
- Central Venous Catheters and Hemodialysis
- Health Systems, Economic Evaluations, Quality of Life
- Renal and Vascular Pathologies
- Patient-Provider Communication in Healthcare
- Management of metastatic bone disease
- Healthcare Quality and Management
McMaster University
2016-2025
Impact
2018-2025
St. Joseph’s Healthcare Hamilton
2008-2025
University of Ottawa
2021-2024
Juravinski Hospital
2010-2024
University Hospital Centre Zagreb
2014-2024
University of Toronto
1996-2024
Population Health Research Institute
2015-2024
Hamilton Health Sciences
2012-2024
Northwestern University
2016-2023
Abstract Background: Myocardial injury after noncardiac surgery (MINS) was defined as prognostically relevant myocardial due to ischemia that occurs during or within 30 days surgery. The study’s four objectives were determine the diagnostic criteria, characteristics, predictors, and 30-day outcomes of MINS. Methods: In this international, prospective cohort study 15,065 patients aged 45 yr older who underwent in-patient surgery, troponin T measured first 3 postoperative days. Patients with a...
<h3>Importance</h3> Chemoradiotherapy (CRT), followed by surgery, is the recommended approach for stage II and III rectal cancer. While CRT decreases risk of local recurrence, it does not improve survival leads to poorer functional outcomes than surgery alone. Therefore, new approaches better select patients are important. <h3>Objective</h3> To conduct a phase 2 study evaluate safety feasibility using magnetic resonance imaging (MRI) criteria with "good prognosis" tumors primary surgery....
Importance Over the last 2 decades, increasing use of multimodal strategies has led to significant improvements in oncologic outcomes for patients with rectal cancer. However, uptake these varies among centers, suggesting that best evidence is not always implemented into practice. Objectives To identify gaps care and initiate knowledge translation interventions close existing gaps. Design, Setting, Participants This 3-year multifaceted, prospective quality improvement study was conducted at...
This study assessed lymph node counts, status (positive or negative), and survival among patients undergoing colon cancer surgery in Ontario, Canada.We obtained data from the Ontario Cancer Registry on 960 who underwent a major resection years 1991-1993. Patients hospitals were ranked by count to correlate counts status. For node-negative we influence of patient, hospital, tumor factors survival.The rate node-positive was similar groups. example, odds ratio patient being positive if 10-36...
Acute bacterial gastroenteritis is associated with subsequent post-infectious irritable bowel syndrome (PI-IBS) in adults. Less known about this relationship children. In May 2000, contamination of municipal water by Escherichia coli 0157:H7 and Campylobacter species caused a large outbreak acute Walkerton, Ontario. We assessed association among cohort children enrolled the Walkerton Health Study (WHS).WHS participants who were under age 16 at time but reached during 8-year study follow-up...
PURPOSE: The number of lymph nodes examined has been proposed as a quality benchmark for colon cancer surgery, although it is unknown whether this strategy reduces understaging. METHODS: We identified 11,044 patients who underwent surgery with pT3 wall penetration between 1988 and 2003 from the Surveillance, Epidemiology End Results registry. determined proportion were node positive each count. used logistic regression to predict odds being by count after adjusting confounders. joinpoint...
To evaluate physicians' adjustments of insulin pump settings based on continuous glucose monitoring (CGM) for patients with type 1 diabetes and to compare these automated dose adjustments.A total 26 physicians from 16 centres in Europe, Israel South America participated the study. All were asked adjust dosing pump, CGM glucometer downloads 15 (mean age 16.2 ± 4.3 years, six female, mean glycated haemoglobin 8.3 0.9% [66.8 7.3 mmol/mol]) gathered over a 3-week period. Recommendations compared...
Abstract Objective To determine if virtual care with remote automated monitoring (RAM) technology versus standard increases days alive at home among adults discharged after non-elective surgery during the covid-19 pandemic. Design Multicentre randomised controlled trial. Setting 8 acute hospitals in Canada. Participants 905 (≥40 years) who resided areas mobile phone coverage and were to be from hospital either RAM (n=451) or (n=454). 903 participants (99.8%) completed 31 day follow-up....
Importance Although major bleeding is among the most common and prognostically important perioperative complications, relative timing of events not well established. This information critical for preventing complications informing pharmacologic thromboprophylaxis. Objective To determine postoperative patients undergoing surgery up to 30 days after surgery. Design, Setting, Participants a secondary analysis prospective cohort study. Patients aged 45 years or older who underwent inpatient...
Abstract Background Radiation is being used increasingly in the management of patients with rectal cancer. Over past decade Basingstoke Colorectal Research Unit has combined precision total mesorectal excision highly selective use preoperative radiotherapy. Methods One hundred and fifty consecutive who underwent major surgical for cancers all stages comprised study group. Preoperative clinical assessment was based largely on tumour size, fixation distance from anal verge. Only radiotherapy...
OBJECTIVE: To determine, for abdominal aortic aneurysm surgery, whether a previously reported relationship between hospital case volume and mortality rate was observed in Ontario hospitals to assess the potential impact of age on elective surgery. DESIGN: Population based observational study using administrative data. SETTING: All where repair as primary procedure performed during 1988-92. PATIENTS: These comprised 5492 patients with unruptured aneurysms 1203 ruptured admitted 1988-92...
There is evidence of gaps in care for colorectal cancer surgery related to obtaining negative resection margins and lymph node assessment. Recommendations on the surgical pathological management curable colon rectal were developed.A systematic review nodes was conducted. This evidence, combined with from existing guidelines expert consensus, used develop recommendations. The draft guideline reviewed by an panel externally practitioners Ontario, Canada.The search recent literature identified...