- Venous Thromboembolism Diagnosis and Management
- Atrial Fibrillation Management and Outcomes
- Platelet Disorders and Treatments
- Acute Myocardial Infarction Research
- Blood groups and transfusion
- Heparin-Induced Thrombocytopenia and Thrombosis
- Systemic Lupus Erythematosus Research
- Blood Coagulation and Thrombosis Mechanisms
- Renal Diseases and Glomerulopathies
- Central Venous Catheters and Hemodialysis
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac, Anesthesia and Surgical Outcomes
- Sepsis Diagnosis and Treatment
- Blood transfusion and management
- Acute Ischemic Stroke Management
- Genetic factors in colorectal cancer
- Diagnosis and Treatment of Venous Diseases
- Meta-analysis and systematic reviews
- Clinical practice guidelines implementation
- Cancer Genomics and Diagnostics
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Hemoglobinopathies and Related Disorders
- Ultrasound in Clinical Applications
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Multiple and Secondary Primary Cancers
McMaster University
2016-2025
Prince of Wales Hospital
2025
Universität Hamburg
2024
University Medical Center Hamburg-Eppendorf
2024
University of Birmingham
2024
Hamilton Regional Laboratory Medicine Program
2023
St. Joseph’s Healthcare Hamilton
2005-2021
Thrombosis and Atherosclerosis Research Institute
2012-2020
Hamilton Health Sciences
2010-2016
ENT and Allergy
2016
Abstract Background: Despite an increase in the number of therapies available to treat patients with immune thrombocytopenia (ITP), there are minimal data from randomized trials assist physicians management patients. Objective: These evidence-based guidelines American Society Hematology (ASH) intended support patients, clinicians, and other health care professionals their decisions about ITP. Methods: In 2015, ASH formed a multidisciplinary guideline panel that included 8 adult clinical...
Abstract Background: Although an increased cancer risk in Peutz-Jeghers syndrome is established, data on the spectrum of tumors associated with disease and influence germ-line STK11/LKB1 (serine/threonine kinase) mutation status are limited. Experimental Design: We analyzed incidence 419 individuals syndrome, 297 had documented mutations. Results: Ninety-six cancers were found among syndrome. The for developing at ages 20, 30, 40, 50, 60, 70 years was 2%, 5%, 17%, 31%, 60%, 85%,...
Antiphospholipid antibodies are autoantibodies directed against proteins that bind to phospholipid. antibody syndrome (APS) refers the association between antiphospholipid and thrombosis risk or pregnancy morbidity. Patients with APS may be at increased of recurrent arterial venous loss.To systematically review evidence for treatment in patients APS.Search MEDLINE (1966 November 2005) Cochrane Library electronic databases (2005) reference lists randomized trials, meta-analyses prospective...
Objectives: To identify risk factors for failure of anticoagulant thromboprophylaxis in critically ill patients the ICU. Design: Multivariable regression analysis thrombosis predictors from a randomized trial. Setting: Sixty-seven medical-surgical ICUs six countries. Patients: Three thousand seven hundred forty-six patients. Interventions: All received with low-molecular-weight heparin or unfractionated at standard doses. Measurements and Main Results: Independent venous thromboembolism,...