- Venous Thromboembolism Diagnosis and Management
- Atrial Fibrillation Management and Outcomes
- Acute Ischemic Stroke Management
- Diagnosis and Treatment of Venous Diseases
- Central Venous Catheters and Hemodialysis
- Blood Coagulation and Thrombosis Mechanisms
- Ultrasound in Clinical Applications
- Acute Myocardial Infarction Research
- Peripheral Artery Disease Management
- COVID-19 Clinical Research Studies
- Vascular Procedures and Complications
- Clinical practice guidelines implementation
- Vascular anomalies and interventions
- COVID-19 and healthcare impacts
- Healthcare Systems and Practices
- Antiplatelet Therapy and Cardiovascular Diseases
- Health Systems, Economic Evaluations, Quality of Life
- Congenital Heart Disease Studies
- Radiation Dose and Imaging
- Heparin-Induced Thrombocytopenia and Thrombosis
- Cerebrovascular and Carotid Artery Diseases
- Meta-analysis and systematic reviews
- Reliability and Agreement in Measurement
- Cardiovascular Effects of Exercise
- Infective Endocarditis Diagnosis and Management
University Hospital of Geneva
2016-2025
Geneva College
2005-2025
Hôpital Beau-Séjour
2014-2024
University of Geneva
2012-2024
HES-SO Genève
2005-2021
Ospedale G.B. Morgagni - L.Pierantoni
2021
Centre Hospitalier Universitaire de Nîmes
2021
Polskie Towarzystwo Gastroenterologii
2020
Civil Service
2017
Service de la Santé Publique
2004-2015
Guidelines summarize and evaluate available evidence with the aim of assisting health professionals in proposing best management strategies for an individual patient a given condition. their recommendations should facilitate decision making daily practice. However, final decisions concerning must be made by responsible professional(s) consultation caregiver as appropriate.
<b>New @ESCardio Guidelines for the Diagnosis and Management of Acute #PulmonaryEmbolism developed in collaboration with @EuroRespSoc now available: #cardiotwitter @erspublications</b>http://bit.ly/2HnrJaj
Background: Diagnosis of pulmonary embolism requires clinical probability assessment. Implicit assessment is accurate but not standardized, and current prediction rules have shortcomings. Objective: To construct a simple score based entirely on variables independent from physicians' implicit judgment. Design: Derivation external validation the in 2 management studies diagnosis. Setting: Emergency departments 3 university hospitals Europe. Patients: Consecutive patients admitted for...
D-dimer measurement is an important step in the diagnostic strategy of clinically suspected acute pulmonary embolism (PE), but its clinical usefulness limited elderly patients.To prospectively validate whether age-adjusted cutoff, defined as age × 10 patients 50 years or older, associated with increased yield PE.A multicenter, multinational, prospective management outcome study 19 centers Belgium, France, Netherlands, and Switzerland between January 1, 2010, February 28, 2013.All consecutive...
Background: Coronavirus disease 2019 (COVID-19)–related critical illness and acute are associated with a risk of venous thromboembolism (VTE). Objective: These evidence-based guidelines the American Society Hematology (ASH) intended to support patients, clinicians, other health care professionals in decisions about use anticoagulation for thromboprophylaxis patients COVID-19–related who do not have confirmed or suspected VTE. Methods: ASH formed multidisciplinary guideline panel applied...
<b>Objectives</b> In older patients, the D-dimer test for pulmonary embolism has reduced specificity and is therefore less useful. this study a new, age dependent cut-off value was devised its usefulness with patients assessed. <b>Design</b> Retrospective multicentre cohort study. <b>Setting</b> General teaching hospitals in Belgium, France, Netherlands, Switzerland. <b>Patients</b> 5132 consecutive clinically suspected embolism. <b>Intervention</b> Development of new point aged >50 years...
Summary Practice guidelines recommend outpatient care for selected patients with non-massive pulmonary embolism (PE), but fail to specify how these low-risk should be identified. Using data from U.S. patients, we previously derived the Pulmonary Embolism Severity Index (PESI), a prediction rule that risk stratifies PE. We sought validate PESI in European patient cohort. prospectively validated PE diagnosed at six emergency departments three countries. used baseline rule’s 11 prognostic...
The revised Geneva score is a fully standardized clinical decision rule (CDR) in the diagnostic workup of patients with suspected pulmonary embolism (PE). variables have different weights, which could lead to miscalculations an acute setting. We validated simplified version score.Data from 1049 2 large prospective trials that included PE were used and combined validate score. constructed CDR by attributing 1 point each item original compared accuracy versions receiver operating...
c It is recommended that recognition be given patients with PAD have a high risk of vascular events in other beds.(Evidence Level A), and as such these should always considered for further events.(Level A, class I) 12 In PAD, it optimization treatment the concomitant coronary artery disease cardiac failure undertaken.(Evidence B, renal failure, attention paid to presence arteriosclerosis (atherosclerosis plus calcification) lower limb, this patient population has poorer prognosis.(Evidence...
<b>Objective</b> To prospectively validate the HERDOO2 rule (Hyperpigmentation, Edema, or Redness in either leg; D-dimer level ≥250 μg/L; Obesity with body mass index ≥30; Older age, ≥65 years), which states that women none one of criteria can safely discontinue anticoagulants after short term treatment. <b>Design</b> Prospective cohort management study. <b>Setting</b> 44 secondary tertiary care centres seven countries. <b>Participants</b> Of 3155 consecutive eligible...
The short-term prognosis of pulmonary embolism (PE) depends on hemodynamic status and underlying disease. prognostic value right ventricular dysfunction injury is less well established.To evaluate factors PE in a multicenter prospective cohort study.Echocardiography, brain natriuretic peptide (BNP), N-terminal-proBNP cardiac troponin I measurements were done admission 570 consecutive patients with an acute PE. A predictive model was based independent predictors 30-day adverse events defined...
Summary The presence of a clot – even asymptomatic in the proximal lower limb veins patient with clinically suspected pulmonary embolism (PE) provides evidence for venous thromboembolism and indicates anticoagulant therapy such patients. We aimed at assessing diagnostic performance compression ultrasonography as compared to multi-slice computed tomography (MSCT) diagnosis PE. analyzed data from large outcome management study that included consecutive outpatients referred emergency ward All...