A5102829136- Pneumonia and Respiratory Infections
- Emergency and Acute Care Studies
- Respiratory viral infections research
- Healthcare Policy and Management
- Sepsis Diagnosis and Treatment
- Pneumocystis jirovecii pneumonia detection and treatment
- Primary Care and Health Outcomes
- Smoking Behavior and Cessation
- Nosocomial Infections in ICU
- Venous Thromboembolism Diagnosis and Management
- Acute Myocardial Infarction Research
- Atrial Fibrillation Management and Outcomes
- Opioid Use Disorder Treatment
- Patient Satisfaction in Healthcare
- Chronic Disease Management Strategies
- Dialysis and Renal Disease Management
- Heart Failure Treatment and Management
- Pain Management and Opioid Use
- Pharmaceutical Practices and Patient Outcomes
- Health Systems, Economic Evaluations, Quality of Life
- Influenza Virus Research Studies
- Acute Ischemic Stroke Management
- Acute Kidney Injury Research
- Antibiotic Use and Resistance
- Global Public Health Policies and Epidemiology
University of Pittsburgh
2015-2024
VA Pittsburgh Healthcare System
2015-2024
University of Pittsburgh Medical Center
1990-2021
Veterans Health Administration
2021
Michael & Associates
2021
Blackstone (United States)
2020
Centre for Health Equity Studies
2012-2017
Office of Patient Care Services
2016
Portland VA Medical Center
2016
UPMC Montefiore
2000-2015
There is considerable variability in rates of hospitalization patients with community-acquired pneumonia, part because physicians' uncertainty assessing the severity illness at presentation.From our analysis data on 14,199 adult inpatients we derived a prediction rule that stratifies into five classes respect to risk death within 30 days. The was validated 1991 38,039 and 2287 outpatients Pneumonia Patient Outcomes Research Team (PORT) cohort study. assigns points based age presence...
Section:ChooseTop of pageAbstract <<ContentsOverviewIntroductionMethodsRecommendationsConclusionsReferencesCITING ARTICLES
John G. Bartlett,1 Scott F Dowell,2 Lionel A. Mandell,6 Thomas M. File, Jr.,3 Daniel Musher,4 and Michael J. Fine5 'Johns Hopkins University School of Medicine, Baltimore, Maryland, 2Centers for Disease Control Prevention, Atlanta, Georgia, 3Northeastern Ohio Universities College Cleveland, Ohio, 4Baylor Medicine Veterans Affairs Medical Center, Houston, Texas, 5University Pittsburgh, Pennsylvania, USA; 6McMaster University, Toronto, Canada
To systematically review the medical literature on prognosis and outcomes of patients with community-acquired pneumonia (CAP).A MEDLINE search English-language articles involving human subjects manual reviews article bibliographies were used to identify studies in CAP.Review 4573 citations revealed 122 (127 unique study cohorts) that reported adults CAP.Qualitative assessments studies' patient populations, designs, performed. Summary univariate odds ratios (ORs) rate differences (RDs) their...
An objective and simple prognostic model for patients with pulmonary embolism could be helpful in guiding initial intensity of treatment.To develop a clinical prediction rule that accurately classifies into categories increasing risk mortality other adverse medical outcomes.We randomly allocated 15,531 inpatient discharges from 186 Pennsylvania hospitals to derivation (67%) internal validation (33%) samples. We derived our using logistic regression 30-day as the primary outcome, patient...
Fang, Guo-Dong M.D.; Fine, Michael M.D., M.Sc.; Orloff, John Arisumi, David Yu, Victor L. Kapoor, Wishwa M.P.H.; Grayston, J. Thomas Wang, San Pin D.Sc.; Kohler, Richard Muder, Robert R. Yee, Ying C. M.S.; Rihs, D. B.S.; Vickers, M. B.S. Author Information
▪Objectives: To study the effect of previously administered antibiotics on antibiotic susceptibility profile Enterobacter, factors affecting mortality, and emergence resistance during therapy for Enterobacter bacteremia. ▪Design: Prospective, observational consecutive patients with ▪Setting: Three university tertiary care centers, one major university-affiliated hospital, two Veterans Affairs medical centers. ▪Patients: A total 129 adult were studied. ▪Measurements: The main end points...
The prevalence, severity, and clinical significance of physical emotional symptoms in patients who are on maintenance hemodialysis remain incompletely characterized. This study sought to assess their relationship quality life depression. recently developed Dialysis Symptom Index was used the presence severity 30 symptoms. Illness Effects Questionnaire Beck Depression Inventory were evaluate depression, respectively. Correlations among symptom burden, life, depression assessed using Spearman...
Although medical practice guidelines exist, there have been no large-scale studies assessing the relationship between initial antimicrobial therapy and outcomes for patients hospitalized with pneumonia.To determine associations 30-day mortality these patients.Hospital records 12945 Medicare inpatients (> or = 65 years of age) pneumonia were reviewed. Associations regimens assessed Cox proportional hazards models, adjusting baseline differences in patient characteristics, illness severity,...
Existing severity assessment tools, such as the pneumonia index (PSI) and CURB-65 (tool based on confusion, urea level, respiratory rate, blood pressure, age >or=65 years), predict 30-day mortality in community-acquired (CAP) have limited ability to which patients will require intensive or vasopressor support (IRVS).The Australian CAP Study (ACAPS) was a prospective study of 882 episodes each patient had detailed features, etiology, treatment outcomes. Multivariate logistic regression...
Electronic cigarettes (e-cigarettes) may help smokers reduce the use of traditional combustible cigarettes. However, adolescents and young adults who have never smoked are now using e-cigarettes, these individuals be at risk for subsequent progression to cigarette smoking.To determine whether baseline e-cigarettes among nonsmoking nonsusceptible is associated with along an established trajectory smoking.In this longitudinal cohort study, a national US sample 694 participants aged 16 26 years...
Background— Community-acquired pneumonia (CAP) affects >5 million adults each year in the United States. Although incident cardiac complications occur patients with community-acquired pneumonia, their incidence, timing, risk factors, and associations short-term mortality are not well understood. Methods Results— A total of 1343 inpatients 944 outpatients were followed up prospectively for 30 days after presentation. Incident (new or worsening heart failure, new arrhythmias, myocardial...
The effect of procalcitonin-guided use antibiotics on treatment for suspected lower respiratory tract infection is unclear.In 14 U.S. hospitals with high adherence to quality measures the pneumonia, we provided guidance clinicians about national clinical practice recommendations infections and interpretation procalcitonin assays. We then randomly assigned patients who presented emergency department a whom treating physician was uncertain whether antibiotic therapy indicated one two groups:...
Summary Practice guidelines recommend outpatient care for selected patients with non-massive pulmonary embolism (PE), but fail to specify how these low-risk should be identified. Using data from U.S. patients, we previously derived the Pulmonary Embolism Severity Index (PESI), a prediction rule that risk stratifies PE. We sought validate PESI in European patient cohort. prospectively validated PE diagnosed at six emergency departments three countries. used baseline rule’s 11 prognostic...
Although several studies have found that the burden of symptoms in patients who are on maintenance hemodialysis is substantial, little known about renal providers' awareness these symptoms. The aim this study was to assess provider recognition and their severity patients.The Dialysis Symptom Index, a 30-item measure severity, administered during routine session. Immediately after surveying patients, evaluated patient completed Index report he or she believed were present patient....
Despite the significant medical and economic consequences of coexisting alcohol use disorder (AUD) in patients with cirrhosis, little is known about AUD treatment patterns their impact on clinical outcomes this population. We aimed to characterize associated cirrhosis.This retrospective cohort study included Veterans cirrhosis who received Health Administration care had an index diagnosis between 2011 2015. assessed baseline factors (pharmacotherapy or behavioral therapy) for 180 days...
To our knowledge, no previous study has systematically examined pneumonia-related and pneumonia-unrelated mortality. This was performed to identify the cause(s) of death compare timing risk factors associated with mortality.For all deaths within 90 days presentation, a synopsis events preceding independently reviewed by 2 members 5-member review panel (C.M.C., D.E.S., T.J.M., W.N.K., M.J.F.). The underlying immediate causes whether pneumonia had major, minor, or apparent role in were...
Despite careful evaluation of changes in hospital care for community-acquired pneumonia (CAP), little is known about intensive unit (ICU) use the treatment this disease. There are criteria that define CAP as “severe,” but their predictive value limited. We compared characteristics, course, and outcome inpatients who did (n = 170) not 1,169) receive ICU Pneumonia Patient Outcomes Research Team prospective cohort. also assessed characteristics four prediction rules (the original revised...