A5024271503- Reproductive tract infections research
- Syphilis Diagnosis and Treatment
- HIV/AIDS Research and Interventions
- Mosquito-borne diseases and control
- Urinary Tract Infections Management
- Adolescent Sexual and Reproductive Health
- Cervical Cancer and HPV Research
- Global Maternal and Child Health
- HIV, Drug Use, Sexual Risk
- Sex work and related issues
- SARS-CoV-2 detection and testing
- Viral Infections and Outbreaks Research
- HIV Research and Treatment
- Viral Infections and Vectors
- Hepatitis B Virus Studies
- Malaria Research and Control
- Parasites and Host Interactions
- Respiratory viral infections research
- Hepatitis C virus research
- Biosensors and Analytical Detection
- Ethics in Clinical Research
- Viral gastroenteritis research and epidemiology
- Bacterial Identification and Susceptibility Testing
- Biotechnology and Related Fields
- HIV/AIDS drug development and treatment
London School of Hygiene & Tropical Medicine
2016-2025
University of London
2013-2025
University of Manitoba
1994-2024
Britest (United Kingdom)
2023
Australian Regenerative Medicine Institute
2023
Monash University
2023
Africa Centres for Disease Control and Prevention
2023
Johns Hopkins University
2017
World Health Organization
2003-2016
Centers for Disease Control and Prevention
1999-2016
Better access to tuberculosis testing is a key priority for fighting tuberculosis, the leading cause of infectious disease deaths in people. Despite roll-out molecular WHO-recommended rapid diagnostics replace sputum smear microscopy over past decade, large diagnostic gap remains. Of estimated 10·6 million people who developed globally 2022, more than 3·1 were not diagnosed. An exclusive focus on improving test accuracy alone will be sufficient close tuberculosis. Diagnostic yield, which we...
We previously reported that laboratory reference strains of Chlamydia trachomatis differing in infection organotropism correlated with inactivating mutations the pathogen's tryptophan synthase (trpBA) genes. Here, we have applied functional genomics to extend this work and find paradigm established for serovars also applies clinical isolates — specifically, all ocular trachoma tested synthase, whereas genital encode a enzyme. Moreover, enzyme activity was directly IFN-γ resistance through an...