A5089206390- Reproductive tract infections research
- Ophthalmology and Visual Impairment Studies
- Cervical Cancer and HPV Research
- Syphilis Diagnosis and Treatment
- Glaucoma and retinal disorders
- Retinal Diseases and Treatments
- Retinal Imaging and Analysis
- Urinary Tract Infections Management
- Retinal Development and Disorders
- Connexins and lens biology
- Adolescent Sexual and Reproductive Health
- Balance, Gait, and Falls Prevention
- Older Adults Driving Studies
- Traffic and Road Safety
- Global Maternal and Child Health
- Reproductive System and Pregnancy
- Ocular Surface and Contact Lens
- Pediatric health and respiratory diseases
- Ergonomics and Musculoskeletal Disorders
- Retinal and Optic Conditions
- Herpesvirus Infections and Treatments
- Urban Transport and Accessibility
- Pneumonia and Respiratory Infections
- Intraocular Surgery and Lenses
- Ophthalmology and Visual Health Research
Johns Hopkins University
2015-2024
Johns Hopkins Medicine
2015-2024
Johns Hopkins Hospital
2010-2024
Dana (United States)
1989-2023
Smith-Kettlewell Eye Research Institute
2023
Direction de la Météorologie Nationale du Niger
2021
National Eye Institute
2004-2020
Gates Foundation
2016-2020
Fred Hollows Foundation
2020
Instituto da Visão
2020
OBJECTIVES: Previous cross‐sectional studies have shown a correlation between falls and fear of falling, but it is unclear which comes first. Our objectives were to determine the temporal relationship see whether these two outcomes share predictors. DESIGN: A 20‐month, population‐based, prospective, observational study. SETTING: Salisbury, Maryland. Each evaluation consisted home‐administered questionnaire, followed by 4‐ 5‐hour clinic evaluation. PARTICIPANTS: The 2,212 participants in...
To investigate the relation of ultraviolet radiation and cataract formation, we undertook an epidemiologc survey 838 watermen (mean age, 53 years) who worked on Chesapeake Bay. The annual ocular exposure was calculated from age 16 for each waterman by combining a detailed occupational history with laboratory field measurements sun exposure. Cataracts were graded ophthalmologic examination both type severity. Some degree cortical found in 111 (13 percent), some nuclear 229 (27 percent)....
<h3>Objective</h3> To determine the prevalence and causes of low vision in a large sampleof nursing home residents. <h3>Methods</h3> Twenty-eight homes on Eastern Shore Maryland Delawarewere enrolled clinical trial to assess impact restoration/rehabilitationon Visual acuity was measured using both recognitioncharts preferential looking techniques. An ophthalmologist examined allresidents with visual worse than 20/40 better-seeing eye anddetermined primary cause for decreased vision. Results...
Objectives: To determine the prevalence of cataract and pseudophakia/aphakia in United States to project expected change these figures by 2020.Methods: Summary estimates were prepared separately for black, white, Hispanic persons (for whom only surgery data available) 5-year age intervals starting at 40 years women men.The based on a standardized definition various types cataract: cortical, greater than 25% lens involved; posterior subcapsular, present according grading system used each...
Purpose: To examine the distribution and association of dry eye symptoms, Schirmer test results, rose bengal scores in a population-based sample elderly Americans. Design: Population-based prevalence survey. Participants: Involved were 2240 noninstitutionalized residents Salisbury, Maryland, aged 65 years older as September 1993, identified by Health Care Financing Administration Medicare database. Main Outcome Measures: A standardized symptom questionnaire, scoring ocular surface staining,...
To determine the association between performance on selected tasks of everyday life and impairment in visual acuity contrast sensitivity.Visual sensitivity were obtained a population-based sample 2520 older African American white subjects. Performance was assessed mobility, daily activities with strong component, visually intensive tasks. Disability defined as less than 1 SD below mean. Receiver operating characteristic curve analyses used to evaluate specificity thresholds loss for...
We hypothesized that mass distribution of a broad-spectrum antibiotic agent to preschool children would reduce mortality in areas sub-Saharan Africa are currently far from meeting the Sustainable Development Goals United Nations.
To complete the baseline trachoma map worldwide by conducting population-based surveys in an estimated 1238 suspected endemic districts of 34 countries.A series national and sub-national projects owned, managed staffed ministries health, conduct house-to-house cluster random sample evaluation units, which generally correspond to "health district" size: populations 100,000-250,000 people. In each unit, we invite all residents aged 1 year older from h households c clusters be examined for...
<h3>Importance</h3> Worsening vision and declining cognitive functioning are common conditions among elderly individuals. Understanding the association between them could be beneficial in mitigating age-related changes. <h3>Objective</h3> To evaluate longitudinal associations visual impairment function over time a population-based study of older US adults. <h3>Design, Setting, Participants</h3> Prospective adults greater Salisbury area Maryland. Overall, 2520 community-residing aged 65 to 84...
We previously reported that laboratory reference strains of Chlamydia trachomatis differing in infection organotropism correlated with inactivating mutations the pathogen's tryptophan synthase (trpBA) genes. Here, we have applied functional genomics to extend this work and find paradigm established for serovars also applies clinical isolates — specifically, all ocular trachoma tested synthase, whereas genital encode a enzyme. Moreover, enzyme activity was directly IFN-γ resistance through an...
To establish the relationship between ultraviolet-B radiation and squamous cell carcinoma (SCC), basal (BCC), actinic keratosis (AK), a cross-sectional prevalence survey was performed in sample of 808 white, male watermen 30 years age older residing Eastern Shore Maryland. A measure personal cumulative exposure determined for each subject from data collected through interviews field laboratory measurements. interview elicited skin type, medication history, other factors. Clinical diagnoses...
Given the importance of driving in American society, older non-drivers may be unable to meet basic needs while living independently. We assessed whether not is an independent risk factor for entering long-term care (LTC) institutions.Data were used from 1593 adults who participated Salisbury Eye Evaluation cohort study and completed additional telephone survey. Questions on status LTC entry obtained by self/proxy report. Cox time-dependent regression procedures adjust demographic health...
As some ultraviolet (UV) radiation is transmitted by the ocular media, there a growing concern that may be possible relationship between long-term exposure to and increased risk of age-related macular degeneration. To address this question, survey was conducted 838 Maryland watermen who had well-characterized UV-A UV-B exposure. Fundus photographs were taken graded for presence exudative disease, geographic atrophy, focal hyperpigmentation retinal pigment epithelium, drusen large and/or...
Trachoma, caused by repeated ocular infection with Chlamydia trachomatis, is an important cause of blindness. Current recommended dosing intervals for mass azithromycin treatment trachoma are based on a mathematical model.We collected conjunctival swabs quantitative polymerase-chain-reaction assay C. trachomatis before and 2, 6, 12, 18, 24 months after in Tanzanian community which was endemic. For ethical reasons, at 18 months, we gave tetracycline eye ointment to residents who had...