Caleb Mpyet

ORCID: 0000-0001-8558-9819
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Research Areas
  • Reproductive tract infections research
  • Cervical Cancer and HPV Research
  • Adolescent Sexual and Reproductive Health
  • Syphilis Diagnosis and Treatment
  • Pediatric health and respiratory diseases
  • Herpesvirus Infections and Treatments
  • Menstrual Health and Disorders
  • Reproductive System and Pregnancy
  • Global Health and Surgery
  • Facial Trauma and Fracture Management
  • Retinal and Optic Conditions
  • Global Maternal and Child Health
  • Ocular Surface and Contact Lens
  • Retinal Imaging and Analysis
  • Dermatology and Skin Diseases
  • Ocular Disorders and Treatments
  • Ocular Diseases and Behçet’s Syndrome
  • Leprosy Research and Treatment
  • Ophthalmology and Visual Health Research
  • Travel-related health issues
  • Virology and Viral Diseases
  • Traumatic Ocular and Foreign Body Injuries
  • Ophthalmology and Visual Impairment Studies
  • Blood donation and transfusion practices
  • COVID-19 Impact on Reproduction

University of Jos
2015-2025

West African College of Physicians
2024

Jos University Teaching Hospital
2006-2022

Ophthalmology Associates (United States)
2021

Sightsavers
2021

University of Cape Town
2018-2020

Groote Schuur Hospital
2019

To complete the baseline trachoma map worldwide by conducting population-based surveys in an estimated 1238 suspected endemic districts of 34 countries.A series national and sub-national projects owned, managed staffed ministries health, conduct house-to-house cluster random sample evaluation units, which generally correspond to "health district" size: populations 100,000-250,000 people. In each unit, we invite all residents aged 1 year older from h households c clusters be examined for...

10.3109/09286586.2015.1037401 article EN Ophthalmic Epidemiology 2015-05-04
Jacqueline Ramke Jennifer Evans Esmael Habtamu Nyawira Mwangi Juan Carlos Silva and 95 more Bonnielin K. Swenor Nathan Congdon Hannah Faal Allen Foster David S. Friedman Stephen Gichuhi Jost B. Jonas Peng T. Khaw Fatima Kyari G. V. S. Murthy Ningli Wang Tien Yin Wong Richard Wormald Mayinuer Yusufu Hugh R. Taylor Serge Resnikoff Sheila K. West Matthew J. Burton AE Aghaji Adeyemi Timothy Adewole Adrienne Csutak Ahmad Shah Salam Ala Paduca A. Bron Alastair K. Denniston Alberto Lazo Legua Aldiana Halim Alemayehu Woldeyes Tefera Alice Mwangi Alicia J. Jenkins Amanda Davis A. Meddeb-Ouertani Amina H Wali Ana Gabriela Palis Ana Bastos de Carvalho Anagha Joshi Andreas Kreis Andreas Mueller Andrew Bastawrous Andrew Cooper Andrew F. Smith Andrzej Grzybowski Anitha Arvind Anne M Karanu Anne O Orlina Anthea Burnett Aryati Yashadhana Asela Abeydeera Aselia Abdurakhmanova Ashik Mohamed Ashish Bacchav Ashlie Bernhisel Aubrey Webson Augusto Azuara‐Blanco Ava Hossain Bayazıt İlhan Bella Assumpta Lucienne Benoît Tousignant B R Shamanna Boateng Wiafe Brigitte Mueller Çağatay Çağlar Caleb Mpyet Carl Halladay Abraham Carol Y. Cheung Cassandra L. Thiel Catherine L Jan Chike Emedike Chimgee Chuluunkhuu Chinomso Chinyere Christin Henein Clare Gilbert Covadonga Bascarán Cristina Elena Nitulescu Daksha Patel Damodar Bachani Daniel Kiage Daniel Etya’ale David N. Dahdal Dawn Woo Lawson Denise Godin Dennis Nkanga Dennis M Ondeyo Donna O’Brien Dorothy M Mutie Ebtisam S K Alalawi Eduardo Mayorga Effendy Bin Hashim Elham Ashrafi Elizabeth Andrew Kishiki Elizabeth Kurian Fabrizio D’Esposito Faith Masila Fernando Yaacov Peña Fortunat Büsch

We undertook a Grand Challenges in Global Eye Health prioritisation exercise to identify the key issues that must be addressed improve eye health context of an ageing population, eliminate persistent inequities health-care access, and mitigate widespread resource limitations.Drawing on methods used previous studies, we multi-step recruitment strategy assemble diverse panel individuals from range disciplines relevant global all regions globally participate three-round, online, Delphi-like,...

10.1016/s2666-7568(21)00302-0 article EN cc-by The Lancet Healthy Longevity 2022-01-01

Background Facial cleanliness and sanitation are postulated to reduce trachoma transmission, but there no previous data on community-level herd protection thresholds. We characterize associations between active trachoma, access improved facilities, water sources for the purpose of face washing, with aim estimating or Methods findings used cluster-sampled Global Trachoma Mapping Project 884,850 children aged 1–9 years from 354,990 households in 13 countries. employed multivariable...

10.1371/journal.pntd.0006110 article EN cc-by PLoS neglected tropical diseases 2018-01-22

In collaboration with the health ministries that we serve and other partners, set out to complete multiple-country Global Trachoma Mapping Project. To maximize accuracy reliability of its outputs, needed in-built, practical mechanisms for quality assurance control. This article describes how those were created deployed. Using expert opinion, computer simulation, working groups, field trials, progressively accumulated in-project experience, external evaluations, developed 1) criteria where...

10.4269/ajtmh.18-0082 article EN cc-by American Journal of Tropical Medicine and Hygiene 2018-07-24

Background Trichiasis is present when one or more eyelashes touches the eye. Uncorrected, it can cause blindness. Accurate estimates of numbers affected, and their geographical distribution, help guide resource allocation. Methods We obtained district-level trichiasis prevalence in adults for 44 endemic previously-endemic countries. used (1) most recent data a district, if than estimate was available; (2) age- sex-standardized corrections historic estimates, where raw were (3) adjusted using...

10.1371/journal.pntd.0007835 article EN cc-by PLoS neglected tropical diseases 2019-11-25
Emma M. Harding‐Esch Clara R. Burgert Cristina Jimenez Ana Bakhtiari Rebecca Willis and 95 more Michael Dejene Bejiga Caleb Mpyet Jeremiah Ngondi Sarah Boyd Mariamo Abdala Amza Abdou Yilikal Adamu Addisu Alemayehu Wondu Alemayehu Tawfik Al-Khatib Sue-Chen Apadinuwe Naomie Awaca Marcel S Awoussi Gilbert Baayendag Mouctar Dieng Badiane Robin L. Bailey Wilfrid Batcho Zulficar Bay Assumpta Lucienne Bella Beido Nassirou Yak Yak Bol Clarisse Bougouma Christopher J. Brady Victor Bucumi Robert Butcher Risiate Cakacaka Anaseini Cama M Camara Eunice Cassama Shorai Grace Chaora Amel Chenaoui Chebbi Alvin Chisambi Brian Chu Abdulai Conteh Sidi Mohamed Coulibaly Paul Courtright Abdi Dalmar Tran Minh Dat Thully Davids Mohamed El Amine Djaker Maria de Fátima Costa Lopes Djoré Dézoumbé Sarity Dodson Philip Downs Stephanie Eckman Bilghis Elkhair Elshafie Mourad Elmezoghi Ange Aba Elvis Paul M. Emerson Emilienne Epée Daniel Faktaufon Mawo Fall Aréty Fassinou Fiona Fleming Rebecca M. Flueckiger Koizan Kadjo Gamael Mackline Garae Jambi Garap Katherine Gass Genet Gebru Michael Gichangi Emanuele Giorgi André Goepogui Daniela Vaz Ferreira Gómez Diana Paola Gómez Forero Emily W. Gower Anna Harte Rob Henry Harvy Alberto Honorio-Morales D Ilako Amadou Alfa Bio Issifou Ellen W. Jones George Kabona Martin Kaboré Boubacar Kadri Khumbo Kalua Sarjo Kanyi Shambel Kebede Fikreab Kebede Jeremy D. Keenan Amir Bedri Kello Asad Aslam Khan Houria Khelifi Janvier Kilangalanga Sung Hye Kim Robert Ko Susan Lewallen Thomas M. Lietman Makoy Samuel Yibi Logora Yuri Andrea Beto lópez Chad MacArthur Colin Macleod Felix Makangila Bréhima Mariko Diana L. Martin

Purpose Population-based prevalence surveys are essential for decision-making on interventions to achieve trachoma elimination as a public health problem. This paper outlines the methodologies of Tropical Data, which supports work undertake those surveys.

10.1080/09286586.2023.2249546 article EN cc-by Ophthalmic Epidemiology 2023-11-02

Background In northern Nigeria, trachoma is an important public health problem, but there are currently few population-based data on prevalence of disease and no formal control programs. Methodology / Principal Findings Kano state, we conducted a cross-sectional survey using multistage cluster random sampling, combining examination for clinical signs application questionnaires assessing potential household-level risk factors. A total 4491 people were examined in 40 clusters, whom 1572 aged...

10.1371/journal.pone.0040421 article EN cc-by PLoS ONE 2012-07-06

Background: There has been discussion regarding the definition of clinical sign trachomatous trichiasis (TT) for purposes determining elimination trachoma as a public health problem, and whether should include presence scarring (TS). Methods: A multi-country comparative cross-sectional study was conducted in settings with varying burdens Ethiopia, Uganda Nigeria to determine if TS grading collected from cases by field graders surveys using simplified scheme are comparable tarsal conjunctival...

10.1101/2025.02.12.25322161 preprint EN cc-by medRxiv (Cold Spring Harbor Laboratory) 2025-02-18

Summary Objective To determine the personal and environmental risk factors associated with trachoma in pre‐school children Yobe state, Nigeria. Methods Total of 639 aged 1–5 from 27 villages were examined their households for clinical signs trachoma. Personal independently determined by an observer while examination was being performed. Results The prevalence active 35.7% (95% CI; 32.0–39.6) disease boys similar to girls. highest 2–3 years age. presence flies on face (OR 4.14; CI 2.72–6.29)...

10.1111/j.1365-3156.2009.02436.x article EN Tropical Medicine & International Health 2010-01-12

Purpose: We sought to determine the prevalence of trachoma in 44 Local Government Areas (LGAs) Kano State, Nigeria.Methods: A population-based survey was conducted each LGA. used a two-stage systematic and quasi-random sampling strategy select 25 households from clusters All consenting household residents aged 1 year above were examined for trachomatous inflammation–follicular (TF), inflammation–intense (TI) trichiasis.Results: State-wide crude TF persons 1–9 years 3.4% (95% CI 3.3–3.5%),...

10.1080/09286586.2016.1265657 article EN cc-by-nc-nd Ophthalmic Epidemiology 2017-02-28

Background Trachoma is the leading infectious cause of blindness. To reduce transmission, water, sanitation, and hygiene (WaSH) improvements are promoted through a comprehensive public health strategy. Evidence supporting role WaSH in trachoma elimination mixed it remains unknown what coverages needed to effectively transmission. Methods/Findings We used g-computation estimate impact on prevalence trachomatous inflammation—follicular among children aged 1–9 years (TF 1-9 ) when hypothetical...

10.1371/journal.pntd.0011103 article EN cc-by PLoS neglected tropical diseases 2023-02-13

To assess the prevalence of several parasitic infections in Kiribati, dried blood spots collected during trachoma surveys two major population centers 2015, 2016, and 2019 were tested using multiplex bead-based serologic assays to detect IgG antibodies against four pathogens public health interest: Toxoplasma gondii (T. gondii), Taenia solium solium), Strongyloides stercoralis (S. stercoralis), Toxocara canis canis). In Kiritimati Island, seroprevalences T. recombinant antigen for detection...

10.4269/ajtmh.23-0565 article EN cc-by American Journal of Tropical Medicine and Hygiene 2025-02-11

Abstract Background Trachoma, a neglected tropical disease, remains significant public health concern in many regions, particularly sub-Saharan Africa and Yobe State, Nigeria. One approach for elimination involves administering tetracycline eye ointment (TEO) to children <6 months of age as part annual mass drug administration (MDA), aligning with the World Health Organization's ‘A’ component SAFE (Surgery, Antibiotics, Facial hygiene Environmental sanitation) strategy trachoma...

10.1093/inthealth/ihaf014 article EN cc-by International Health 2025-03-13

Purpose: To determine the prevalence of trachoma in each 25 local government areas (LGAs) Niger State, Nigeria.Methods: A population-based cross-sectional survey was conducted State LGA between March and April 2014, as part Global Trachoma Mapping Project (GTMP). GTMP protocols were used planning conduct surveys. Using probability proportional to size, clusters selected; these clusters, households enrolled for survey. All residents aged 1 year older examined by GTMP-certified graders...

10.1080/09286586.2016.1242757 article EN cc-by-nc-nd Ophthalmic Epidemiology 2016-12-05

Objectives To determine the prevalence of diabetes mellitus (DM), diabetic retinopathy (DR) and sight-threatening conditions among persons with DM aged 50 years older in Sohag governorate Upper Egypt. Design Population-based, cross-sectional survey using standardised Rapid Assessment Avoidable Blindness addition Diabetic Retinopathy module methodology. Settings Egypt where 68 clusters were selected probability proportional to population size. Households compact segment technique....

10.1136/bmjopen-2020-047757 article EN cc-by-nc BMJ Open 2021-06-01

To determine the prevalence and types of trachoma in all persons resident Yobe state, Nigeria establish baseline data for monitoring evaluation control programmes.A population based cross-sectional survey 27 villages' selected on probability proportional to size. Three thousand, three hundred fifty seven residing these villages were examined with a x2.5 magnifying binocular loupe trachoma. Trachoma was graded according World Health Organisation grading scheme.Three thousand thirty five...

10.1080/09286580802237633 article EN Ophthalmic Epidemiology 2008-01-01

Purpose: To determine the local government area (LGA)-level prevalence of trachoma in all 34 LGAs Katsina State.Methods: A population-based survey was conducted each LGA State, using Global Trachoma Mapping Project methodology. We used a 3-stage cluster random sampling strategy to select 25 households from clusters. examined residents selected aged 1 year and older for clinical signs trachomatous inflammation–follicular (TF), inflammation–intense trichiasis, World Health Organization (WHO)...

10.1080/09286586.2016.1236975 article EN cc-by-nc-nd Ophthalmic Epidemiology 2016-10-24

Purpose: To determine the prevalence of trachomatous inflammation – follicular (TF) and trichiasis in each 20 local government areas (LGAs) Bauchi State, Nigeria.Methods: We undertook a population-based survey LGA employing Global Trachoma Mapping Project methodology. used 2-stage, systematic quasi-random sampling strategy. Using probability proportional to size, we selected 25 clusters, which households were by random walk. All residents 1 year older examined for TF, intense, trichiasis,...

10.1080/09286586.2016.1238945 article EN cc-by-nc-nd Ophthalmic Epidemiology 2016-11-15

Purpose: To determine the need or otherwise for establishment of a trachoma elimination program in Gombe State, Nigeria, by estimating population-based prevalence each Local Government Area (LGA) Gombe.Methods: Using multi-stage, systematic, random, and quasi-random sampling approach Global Trachoma Mapping Project support, we selected 25 clusters LGA. In cluster, households all consenting residents aged 1 year older were examined trachomatous inflammation–follicular (TF) trichiasis, using...

10.1080/09286586.2016.1230633 article EN cc-by-nc-nd Ophthalmic Epidemiology 2016-10-11

To prepare for global elimination of trachoma by 2020, the World Health Organization (WHO) recommends mapping at district-level to enable planning activities in affected populations. The aim our study was provide data on each local government area (LGA) Kaduna State, Nigeria, as such were previously unavailable.As part Global Trachoma Mapping Project (GTMP), a population-based cross-sectional survey conducted 23 LGAs between May and June 2013. protocols GTMP used.The prevalence trachomatous...

10.1080/09286586.2016.1250918 article EN cc-by-nc-nd Ophthalmic Epidemiology 2016-12-05

Purpose: To determine the prevalence of trachoma in all suspected endemic districts Malawi.Methods: A population-based survey conducted 16 evaluation units from 12 Malawi (population 6,390,517), using standardized Global Trachoma Mapping Project (GTMP) protocol. 2-stage cluster-random sampling design selected 30 households each clusters per unit; residents aged 1 year and older were examined for evidence follicular (TF), intense trachomatous inflammation (TI), trichiasis (TT).Results: Four...

10.3109/09286586.2015.1035793 article EN Ophthalmic Epidemiology 2015-05-04

Whilst previous work has identified clustering of the active trachoma sign "trachomatous inflammation—follicular" (TF), there is limited understanding spatial structure trachomatous trichiasis (TT), rarer, end-stage, blinding form disease. Here we use community-level TF prevalence, information on access to water and sanitation, large-scale environmental socio-economic indicators model variation in TT prevalence Benin, Cote d'Ivoire, DRC, Guinea, Ethiopia, Malawi, Mozambique, Nigeria, Sudan...

10.1186/s12879-019-3935-1 article EN cc-by BMC Infectious Diseases 2019-04-30
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