Jessica Shelley

ORCID: 0009-0005-3426-8253
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About
Contact & Profiles
Research Areas
  • Cardiac, Anesthesia and Surgical Outcomes
  • Anesthesia and Pain Management
  • Pain Management and Opioid Use
  • Hemodynamic Monitoring and Therapy
  • Spine and Intervertebral Disc Pathology
  • Bone fractures and treatments
  • Reconstructive Surgery and Microvascular Techniques
  • Cancer, Hypoxia, and Metabolism
  • Adenosine and Purinergic Signaling
  • Cardiac Valve Diseases and Treatments
  • Bacterial Infections and Vaccines
  • Non-Invasive Vital Sign Monitoring
  • Blood Pressure and Hypertension Studies
  • Head and Neck Surgical Oncology
  • Nitric Oxide and Endothelin Effects
  • Surgical Simulation and Training
  • Diphtheria, Corynebacterium, and Tetanus
  • Anesthesia and Neurotoxicity Research
  • Respiratory Support and Mechanisms
  • Nausea and vomiting management
  • Advanced ceramic materials synthesis

Queen's University
2021-2024

Population Health Research Institute
2018-2023

University of Alberta
2021

Queens University
2021

Ottawa Hospital
2021

University of Ottawa
2021

Juravinski Hospital
2021

Kingston Health Sciences Centre
2021

Williams (United States)
2021

McMaster University
2021

Abstract Objective To determine if virtual care with remote automated monitoring (RAM) technology versus standard increases days alive at home among adults discharged after non-elective surgery during the covid-19 pandemic. Design Multicentre randomised controlled trial. Setting 8 acute hospitals in Canada. Participants 905 (≥40 years) who resided areas mobile phone coverage and were to be from hospital either RAM (n=451) or (n=454). 903 participants (99.8%) completed 31 day follow-up....

10.1136/bmj.n2209 article EN cc-by-nc BMJ 2021-09-30

The disease has been demonstrated bacteriologically to appear in epidemic and sporadic form. In cases it is difficult frequently impossible, if severe rapidly fatal, differentiate this form of meningitis from that secondary other infectious diseases, except by lumbar puncture, therefore as yet impossible say how extensively the exists 1880 Eberth supposed he had found micrococcus lanceolatus essential cause disease, since then until about 1895 was generally accepted specific cause,...

10.1001/jama.1898.72440780013002a article EN JAMA 1898-06-25

<h3>Background:</h3> After nonelective (i.e., semiurgent, urgent and emergent) surgeries, patients discharged from hospitals are at risk of readmissions, emergency department visits or death. During the coronavirus disease 2019 (COVID-19) pandemic, we undertaking Post Discharge after Surgery Virtual Care with Remote Automated Monitoring Technology (PVC-RAM) trial to determine if virtual care remote automated monitoring (RAM) compared standard will increase number days adult remain alive home...

10.9778/cmajo.20200176 article EN CMAJ Open 2021-01-01

<ns3:p>Background Perioperative thoracic epidural analgesia (TEA) is commonly used in hepatectomy patients since it opioid-sparing and reduces cardiorespiratory complications. However, TEA has a high failure rate associated with potentially devastating complications (particularly spinal haematoma) the risk increased hepatectomy. Thus, some centres favour systemic opioid-based modalities which, turn, are inferior well-known risks/side-effects. Hence, alternative analgesic methods desirable....

10.12688/f1000research.121987.2 preprint EN cc-by F1000Research 2024-06-03

<ns3:p>Background Perioperative thoracic epidural analgesia (TEA) is commonly used in hepatectomy patients since it opioid-sparing. However, TEA has a high failure rate and associated with potentially devastating complications (spinal haematoma) the risk increased hepatectomy. Thus, some centres favour systemic opioid-based modalities which, turn, are inferior well-known risks/side-effects. Hence, alternative analgesic methods desirable. Paravertebral block (PVB) been liver resection...

10.12688/f1000research.121987.3 preprint EN cc-by F1000Research 2024-06-28

Elmdale, Kans., June 28, 1898. <h3>To the Editor:</h3> —An oversight in reading proof of "Cerebro-Spinal Meningitis" allowed sixth line from bottom, first column, page 1499, Vol. xxx, to read "50 per cent." instead "20 Very respectfully,

10.1001/jama.1898.02450020038012 article EN JAMA 1898-07-09

Breast reconstruction is an integral part of breast cancer care. There are 2 main types reconstruction: alloplastic (using implants) and autologous the patient's own tissue). The latter creates a more natural mound avoids long-term need for surgical revision-more often associated with implant-based surgery. deep inferior epigastric perforator (DIEP) flap considered gold standard approach in reconstruction. However, complications do occur DIEP surgery can stem from poor tissue...

10.2196/48576 article EN cc-by JMIR Research Protocols 2023-10-31

<sec> <title>BACKGROUND</title> Breast reconstruction is an integral part of breast cancer care. There are 2 main types reconstruction: alloplastic (using implants) and autologous the patient’s own tissue). The latter creates a more natural mound avoids long-term need for surgical revision—more often associated with implant-based surgery. deep inferior epigastric perforator (DIEP) flap considered gold standard approach in reconstruction. However, complications do occur DIEP surgery can stem...

10.2196/preprints.48576 preprint EN 2023-05-01

Exchange protein directly activated by cAMP (EPAC) is a signaling implicated in several physiologic and pathophysiologic processes. Following binding of cAMP, EPAC activates small GTPases such as Rap1 to induce downstream effects. In vascular endothelial cells, may have role the regulation permeability, tone angiogenesis. As low oxygen tension initiates many events including those modulated EPAC, we hypothesized that hypoxia regulates expression function human microvascular cells (HMVEC)....

10.1096/fasebj.31.1_supplement.1060.8 article EN The FASEB Journal 2017-04-01

<ns7:p><ns7:bold>Background:</ns7:bold> Perioperative thoracic epidural analgesia (TEA) is commonly used in hepatectomy patients since it opioid-sparing and reduces cardiorespiratory complications. However, TEA has a high failure rate associated with potentially devastating complications (particularly spinal haematoma) the risk likely increased hepatectomy. Thus, some centres favour systemic opioid-based modalities which, turn, are inferior well-known risks/side-effects. Hence, alternative...

10.12688/f1000research.121987.1 preprint EN cc-by F1000Research 2022-09-20
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