Background: Placement of cerebrospinal fluid (CSF) shunt for diversion remains a primary treatment patients with hydrocephalus despite its surgical complications, including infection, that remain high and become medical social problem. The meta-analysis was conducted to investigate risk factors infection in pediatrics. Methods: Literature searched on PubMed, Scopus, the Cochrane Library. methodology used this investigation preferred reporting items systematic reviews meta-analysis. Results:...

Background: Traumatic brain injury-related cerebral infarctions are well-documented in the literature. We want to report a case of malignant infarction that occurred at contralateral location evacuated epidural hematoma 3 days after surgery. The early-onset infarction’s clinical presentation was already evident during initial examination, and it resembled “Kernohan’s Notch Syndrome.” Case Description: A 57-year-old male Indonesian taken our Academic General Hospital’s emergency room...

Neuropathic pain may arise from conditions that affecting the central or peripheral nervous system. This study was held to determine difference P2X3 receptor expression in dorsal horn of spinal cord and threshold after estrogen therapy neuropathic pain.

In 2019, a previously unidentified coronavirus was named COVID-19. This virus can infect everyone without exception, including brain injury patients. Because this is relatively new, there have not been many studies examining the interaction of COVID-19 with injury. The purpose study to examine profile patients at Dr. Soetomo Hospital. Method conducted descriptive observational method retrospective approach. data taken came from medical records results 56 COVID-19, majority whom were male,...

Neuropathic pain is a major problem to date because of its high prevalence and lack effective treatment. processes can be influenced by many factors at various levels the nervous system, including progesterone opioid system. The mechanisms effect on are still controversial, while activation system also needs proven. This study aimed determine through modulation mechanism system.This research completely randomized experimental using male wistar rats aged around three months Experimental...

Penyakit Parkinson (PP) adalah penyakit neurodegeneratif paling umum ke dua yang melibatkan hilangnya neuron dopaminergik di otak tengah menyebabkan gejala motorik dan nonmotorik pada pasien mengalaminya. Gejala ini dapat dikelola dikendalikan dalam jangka waktu tertentu dengan menggunakan obat-obatan seperti levodopa. PP mempengaruhi jutaan orang seluruh dunia, oleh karena itu tinjauan pustaka tentang menjadi penting kami akan menyampaikan berbagai hal dari mulai patofisiologi hingga...

Glial Fibrillary Acidic Protein (GFAP) sangat khas untuk otak (highly brain specific protein), sebagai petunjuk kerusakan sel,merupakan protein yang berhubungan dengan peningkatan tekanan intrakranial dan petanda perjalanan penyakit di pasiencedera otak. Penelitian ini menganalisis profil kadar GFAP serum pasien cedera berat dankeluarannya. Desain penelitian deskriptif observasional. Kadar dari sampel darah vena, diperiksa metode ELISApada hari pertama datang ke Instalasi Gawat Darurat...

Introduction: Traumatic brain injury (TBI) has a concerning incidence rate. One of the therapies for patients with TBI is non-steroidal anti-inflammatory drugs (NSAID) administration as an analgesic proper adherence to achieve optimal therapy results. This research aimed evaluate physicians’ NSAID in mild and moderate Dr. Soetomo General Hospital, Surabaya.Methods: was observational descriptive study retrospective design. graded by evaluating dose, route, frequency, interval administration....

The complications of ventriculoperitoneal (VP) shunts are many and reported in literature extensively. complication transanal extrusion after bowel perforation is known although rare. This very well described amongst the children. authors describe case a VP shunt occurring 51-year-old adult patient. patient has history craniotomy for acute subdural hematoma severe head injury one year ago continued with post-traumatic hydrocephalus. Home care bedridden conditions done at home until finally,...

Background: Medulloblastoma is a common neoplasm in the pediatric population with poor prognosis. Incomplete resection has been reported to be related second-look surgery and subsequent more malignant clinical course, while certain histopathological said have favorable Methods: This study retrospectively analyzed data from patients medulloblastoma who underwent tumor our hospital between 2016 2020. Histopathologic information extent of were collected. Survival analysis was done log-rank...

The complications of ventriculoperitoneal (VP) shunts are many and reported in literature extensively. complication transanal extrusion after bowel perforation is known although rare. This very well described amongst the children. authors describe case a VP shunt occurring 51-year-old adult patient. patient has history craniotomy for acute subdural hematoma severe head injury one year ago continued with post-traumatic hydrocephalus. Home care bedridden conditions done at home until finally,...

Background: Trigeminal Neuralgia is a common condition of facial pain and its significantly affect patients’ daily life. Microvascular decompression one the interventional management for trigeminal neuralgia. There still little data obtained on evaluation after microvascular in Indonesia. Objective: This research aimed to evaluate neuralgia patients Dr. Soetomo General Hospital, PHC Bangil Methods: The design was pretest-posttest with total sampling. Data were from medical records January...

Highlight: Until today, Traumatic Brain Injury is still a major cause of death, disability, and serious health issue patients have good quality life if they get adequate therapy on time interventions ABSTRACT Introduction: Approximately 90 million traumatic brain injury (TBI) cases worldwide exist yearly. TBI pathophysiology varies, which may diverse complications. These complications decrease the patients’ life. Objective: Describing brain-injured after being treated at Dr. Soetomo General...

Background: Hydrocephalus is a brain disease that requires prompt treatment. The outcome of hydrocephalus dependent on early detection and This study was conducted to analyze the medico-socio-economic perspective delayed treatment patients, which aimed advance practice neurosurgery in socio-neurosurgery field, including both preventive therapeutic aspects. Method: an observational analysis study. subjects were all patients with congenital treated dr. Soetomo Academic General Hospital between...

Introduction: The new discovery of the active substance in Sargassum sp marks era for drug industry as it is very effective migraine medication compared to analgesics which have already been popular previously treating migraine. By using silico methods, this study intended identify preventive effect within stage pain and inflammation development In pathophysiology, clinical findings would build verify role CGRP TNF-α. Methods: This research applied a one-shot experimental by employing...