A5027596201- Autophagy in Disease and Therapy
- Cardiac Ischemia and Reperfusion
- interferon and immune responses
- Spine and Intervertebral Disc Pathology
- Spinal Hematomas and Complications
- Hydrogen's biological and therapeutic effects
- Ubiquitin and proteasome pathways
- Musculoskeletal pain and rehabilitation
Nanchang University
2021-2024
First Affiliated Hospital of Jiangxi Medical College
2024
First Affiliated Hospital of Nanchang University
2021
Abstract Intestinal ischemia-reperfusion (II/R) injury is an urgent clinical disease with high incidence and mortality, impaired intestinal barrier function caused by excessive apoptosis of cells important cause its serious consequences. Tripartite motif-containing protein 65 (TRIM65) E3 ubiquitin ligase that recently reported to suppress the inflammatory response apoptosis. However, biological regulation TRIM65 in II/R are totally unknown. We found was significantly decreased...
Abstract Intestinal ischemia/reperfusion injury (I/R) is a common yet challenging-to-treat condition, presenting significant clinical challenge. This study aims to investigate the protective mechanisms of Dexmedetomidine (Dex) against I/R injury, with particular focus on its role in regulating autophagy activity intestinal neurons and maintaining mitochondrial homeostasis. Experimental findings demonstrate that Dex can mitigate damage induced by through modulation function suppressing...
This study explored the 10-year efficacy, safety, and prognostic factors of low-dose collagenase chemonucleolysis (CCNL) combined with radiofrequency (RF) in treatment lumbar disc herniation (LDH).The data 167 LDH patients were collected. Modified MacNab criteria, Numerical Rating Scale (NRS), Japanese Orthopedic Association (JOA) scores were, respectively, used to evaluate patients' excellent good rates, pain degree, nerve function. The preoperative postoperative pain, numbness, muscle...