Sepsis occurs in 14-37 percent of patients admitted to intensive care units and sepsis associated encephalopathy (SAE) is its severe complication. In an attempt provide insight into the question how SAE contributes cerebral dysfunction, apoptotic cell death was investigated hippocampal formation, centers adult neurogenesis main autonomic which are known regulate heart rate, respiration other visceral activities, cecal ligation puncture (CLP) rat model sepsis. Vital parameters...

In this study, it was aimed to anatomically examine the fractures of humerus, radius and ulna, which have a significant admission rate in emergency departments, explain relationship between different fracture parameters. The anatomical distribution ulna 239 patients who presented xxx University Hospital 2012 2018 were retrospectively investigated. Participants ages 18-64 years diagnosed with only one bone. It has been found that are more common men 18-44 age group (p

Background/Aim: In the present study, we aimed to compare potential protective effects of thymoquinone and melatonin by using equivalent dose, on oxidative stress-induced ischemia–reperfusion (IR) injury in intestinal tissue rats. Materials Methods: The study was performed 32 male Wistar–Albino rats (weighing 180–200 g) randomly divided into four groups: Group I, sham group; II, IR III, with IV, group. After laparotomy, ischemia reperfusion were for 60 120 min, respectively, all groups....

To assess the usability of lavender oil as an adjuvant in medical treatment pain due to renal stones.One hundred patients age 19-64 years diagnosed with colic were included study. Group 1 (n=50) received standard therapy (diclofenac sodium, 75 mg intramuscularly); group 2 aromatherapy (lavender oil) addition treatment. In both groups, severity was graded between 0 (no pain) and 10 (severe by using visual analogue scale (VAS).The VAS values at beginning 30 minutes 7.70±1.61, 5.02±2.20,...

Malathion can be ingested, inhaled, or absorbed through the skin, but acute toxicity is maximized when administered orally. Intravenous lipid emulsion (ILE) treatment used as a new therapeutic method in cases of systemic caused by some soluble agents. This study aimed to examine potential effect ILE on rat lung tissue toxicokinetic model malathion exposure. Twenty-one adult Wistar albino rats were randomly divided into three equal groups. The groups organized group I (control), II...

Abstract Aim The aim of this study was to investigate the effects carvedilol (CVD) on experimentally induced ovarian ischemia/reperfusion (I/R) injury in rats. Methods An I/R model applied rats, classified into three groups: 1 ( n = 7), sham operated (control); 2 3 h ischemia + reperfusion (I/R); CVD (I/R CVD). Malondialdehyde (MDA) levels and glutathione peroxidase (GSH‐Px) superoxide dismutase (SOD) activities tissues serum were measured. Tissue damage examined histopathologically; Bax...

Aquaporin (AQP) 1 and AQP 4 are expressed in human heart several studies have been focused on these two aquaporins. For this purpose, the present study is aimed to research effects of aging tissue.In study, 14 Balb/C type white mice were used. Animals divided into equal groups. Group I consisted 2-month-old young animals (n=7), group II 18-month-old (n=7). To determine AQP1 AQP4 expression myocardium, tissue was removed perform western blotting immunohistochemical histopathological...

The increased AQP5 expression associated with ageing in glands, which mainly secreted a serous solution, suggests compensation for the decreased amount of saliva secretion age progression.To investigate change aquaporin-1 (AQP1) and aquaporin-5 (AQP5) salivary glands young elder mice.Twelve female mice from Balb/C genus (30-50 g) were used. separated into two groups: Group I had 2-month-old II 18-month-old mice. Salivary (glandula parotidea, glandula sublungualis, submaxillaris) excised...

Intraperitoneal (i.p.) injection is the most frequently used method for implementing parenteral therapies in rats and mice. Whether caecum located right caudal quadrant or left abdominal cavity not clear. For that reason, we have developed a identifying location of mice thus revealed reliable i.p. these animals. Two hundred Wistar albino 100 BALB/c were used. The was determined by revealing intra-abdominal organs immediately following euthanasia, photographing organs, archiving images. Both...

The pathophysiology of necrotizing enterocolitis (NEC) includes the massive production endogenous cytokines with exaggerated activation inflammatory pathways. Ursodeoxycholic acid (UDCA) has been used as an anti-inflammatory, antioxidant, and anti-apoptotic agent. We investigated possible protective effects UDCA in a neonatal rat pup model NEC.We randomly divided pups into three groups: control group, non-treated NEC UDCA-treated group. induced by feeding formula enterally via...

The aim of the present study was to show protective effect pulsed magnetic field (PMF) application and melatonin administration on damage in testis a one-sided torsion detorsion induced rat model using testicular scintigraphy with 99mTc pertechnetate, PET/CT 18F-FDG histopathological methods.Sixty male rats were used study; 30 randomly divided into five groups for one day applications sham control, torsion, melatonin, plus PMF. Similarly, week group, other same group (n=6), but animals...

Objective: This study aims to determine the protective effects of apocynin, a NADPH oxidase inhibitor, and melatonin, an endogenous anti-oxidant, in animal model ovarian ischemia/reperfusion (I/R) injury. Materials/Methods: Thirty-five female rats were randomly divided into five groups, namely group I (sham), II (I/R), III (I/R + 10 mg/kg apocynin), IV 20 V melatonin). Ovarian tissue serum superoxide dismutase (SOD) catalase (CAT) activities malondialdehyde (MDA) protein carbonyl (PC) levels...

Amaç: Aquaporinler su ve iyon transportu sağlayan membran kanal proteinleridir.Yaşlanma ile dokulardaki aquaporinlerin miktarı değişmektedir.Aquaporin-1 (AQP1) aquaporin-3 (AQP3)'ün kıkırdak dokuda yaşlanma azaldığı gösterilmiştir.Ancak kemik miktarında değişim gösterilmemiştir.Bu çalışmada genç yaşlı hayvanların dokularında AQP1, AQP3 tip I kollajen ekspresyonlarının immünohistokimyasal olarak araştırılması amaçlandı.Gereç Yöntem: Bu 14 adet Wistar Albino cinsi sıçan kullanıldı.Grup (n=7)...

Acil servise nörolojik şikayetlerle başvurunun oldukça sık sebeplerinden biri baş ağrısıdır.Subdural hematom genellikle yaşlılarda görülür.Gençlerde subdural nadirdir ve travma sebebiyle oluşur.Gençlerde spontan hematoma ise çok nadiren rastlanır.Bu olguda acil

Acil servise nörolojik şikayetlerle başvurunun oldukça sık sebeplerinden biri baş ağrısıdır.Subdural hematom genellikle yaşlılarda görülür.Gençlerde subdural nadirdir ve travma sebebiyle oluşur.Gençlerde spontan hematoma ise çok nadiren rastlanır.Bu olguda acil

During routine dissection of a 60- 65 years old Caucasian, male cadaver, we found that the ulnarartery is coursing superficially on both forearms. These superficial ulnar arteries (SUA) wereoriginating 2 cm above from termination brachial and were running superficiallyto flexor muscles in forearm. The artery was terminated cubital fossa anddivided as radial, common interosseal recurrent radial arteries. Variations arteries, nerves upper limb are well documented. ofthe most frequent arterial...

Background: Necrotizing enterocolitis (NEC) is a serious intestinal illness in newborns. Objectives: We aimed to investigate the potential protective effects of hesperidin (Hsd) and diosmin on NEC. Methods: Thirty newborn rats were divided into 3 groups: The control group (n = 10), NEC treatment 10). was given 100 mg/kg flavonoid by oral gavage twice daily. On day 5 study, animals sacrificed under anesthesia. After laparotomy, tissue samples obtained from stomach, cecum, ileum. scoring...