A5004021035- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Impact on Reproduction
- Respiratory Support and Mechanisms
- Long-Term Effects of COVID-19
- Cardiac Arrest and Resuscitation
- Organ Transplantation Techniques and Outcomes
- Anesthesia and Sedative Agents
- COVID-19 epidemiological studies
- Mechanical Circulatory Support Devices
- Esophageal and GI Pathology
- Cardiovascular Effects of Exercise
- Renal Transplantation Outcomes and Treatments
- Liver Disease and Transplantation
- Gastroesophageal reflux and treatments
- Blood transfusion and management
- Organ Donation and Transplantation
- Misinformation and Its Impacts
- Injury Epidemiology and Prevention
- Cardiac Structural Anomalies and Repair
- Nausea and vomiting management
- COVID-19 and healthcare impacts
- Dysphagia Assessment and Management
- Intensive Care Unit Cognitive Disorders
- Sports injuries and prevention
WinnMed
2021-2025
Mayo Clinic
2019-2025
St. Luke's Hospital
2025
Mayo Clinic in Arizona
2016-2023
Johns Hopkins University
2012-2021
Cooper Medical School of Rowan University
2021
Cooper University Health Care
2021
Johns Hopkins Medicine
2012
BackgroundConvalescent plasma has been widely used to treat coronavirus disease 2019 (Covid-19) under the presumption that such contains potentially therapeutic antibodies severe acute respiratory syndrome 2 (SARS-CoV-2) can be passively transferred recipient. Whether convalescent with high antibody levels rather than low is associated a lower risk of death unknown.MethodsIn retrospective study based on U.S. national registry, we determined anti–SARS-CoV-2 IgG in hospitalized adults...
BACKGROUND. Convalescent plasma is the only antibody-based therapy currently available for patients with coronavirus disease 2019 (COVID-19). It has robust historical precedence and sound biological plausibility. Although promising, convalescent not yet been shown to be safe as a treatment COVID-19.
Media coverage on coronavirus disease 2019 (COVID-19) has been extensive, yet large gaps remain in our understanding of the role social media platforms during worldwide health crisis. The purpose this study was to assess most viewed YouTube videos COVID-19 for medical content. We coded video characteristics, source, and content 113 most-widely about COVID-19. Seventy-nine (69.9%) were classified as useful, 10 (8.8%) misleading. Independent users more likely post misleading than useful (60.0%...
Background: Convalescent plasma is the only antibody based therapy currently available for COVID-19 patients. It has robust historical precedence and sound biological plausibility. Although promising, convalescent not yet been shown to be safe as a treatment COVID-19. Methods: Thus, we analyzed key safety metrics after transfusion of ABO-compatible human in 5,000 hospitalized adults with severe or life threatening COVID-19, 66% intensive care unit, part US FDA Expanded Access Program plasma....
The United States (US) Expanded Access Program (EAP) to coronavirus disease 2019 (COVID-19) convalescent plasma was initiated in response the rapid spread of severe acute respiratory syndrome 2 (SARS-CoV-2), causative agent COVID-19. While randomized clinical trials were various stages development and enrollment, there an urgent need for widespread access potential therapeutic agents. objective this study is report on demographic, geographical, chronological characteristics patients EAP, key...
Abstract Successful therapeutics and vaccines for coronavirus disease 2019 (COVID-19) have harnessed the immune response to severe acute respiratory syndrome 2 (SARS-CoV-2). Evidence that SARS-CoV-2 exists as locally evolving variants suggests immunological differences may impact effectiveness of antibody-based treatments such convalescent plasma vaccines. Considering near-sourced likely reflects antigenic composition local viral strains, we hypothesize has a higher efficacy, defined by...
As participation in marathon running has increased, there also been concern regarding its safety.To determine if the increase from 2000 to 2009 affected mortality and overall performance.Descriptive epidemiology study.We used publicly available racing news databases analyze number of races, finishing race times, deaths marathons United States.The total finishers increased over this decade 299,018 473,354 2009. The average time remained unchanged (4:34:47 vs 4:35:28; P = .85). Of 3,718,336...
Anesthesiologists are often tasked with overseeing sedation in non-surgical settings. We aim to determine whether adding adjuvant sedatives propofol affects the recovery times and complication rates after endoscopy. conducted a retrospective cohort study of adults (≥18) who received while undergoing Esophagogastroduodenoscopy (EGD) and/or Colonoscopy (COL) at large academic institution over four-year period. Patients receiving alone were compared against patients combination midazolam,...
Anesthetic management of orthotopic liver transplantation (OLT) can be challenging. Management involves responding to sudden hemodynamic shifts, addressing instability, and performing ongoing volume assessment. To best prepare for these perturbations, various monitors are used intraoperatively. We sought explore the impact transesophageal echocardiography (TEE) pulmonary artery catheter (PAC) use on outcomes patients undergoing OLT.We retrospectively reviewed records who underwent OLT at a...
Abstract Background The United States (US) Expanded Access Program (EAP) to COVID-19 convalescent plasma was initiated in response the rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), causative agent disease-2019 (COVID-19). While randomized clinical trials were various stages development and enrollment, there an urgent need for widespread access potential therapeutic agents particularly vulnerable racial ethnic minority populations who disproportionately...
Intracardiac thrombus occurs in 1.2%–6.3% of patients undergoing orthotopic liver transplant and is associated with a high mortality rate. The pathophysiology risk factors for development this complication are not well understood. No consensus treatment guidelines exist, specific therapies serious risks. We present the timely successful use Poole tip surgical suction device advanced into right atrium through cavotomy created inferior vena cava to remove large atrial during transplant. was...
Abstract Successful therapeutics and vaccines for coronavirus disease 2019 (COVID-19) have harnessed the immune response to severe acute respiratory syndrome 2 (SARS-CoV-2). Evidence that SARS-CoV-2 exists as locally evolving variants suggests immunological differences may impact effectiveness of antibody-based treatments such convalescent plasma vaccines. Considering near-sourced is likely reflect antigenic composition local viral strains, we hypothesized has a higher efficacy, defined by...
The assessment of perioperative risk factors for the development acute respiratory distress syndrome (ARDS) has been described in various surgical populations. However, there are only limited data among patients undergoing liver transplantation (LT), particularly regarding influence intraoperative ventilation parameters. We sought to identify associated with ARDS LT recipients.This is a single-center, retrospective cohort study adult who underwent at tertiary academic medical center between...
Introduction: Gastric-to-pulmonary aspiration during esophagogastroduodenoscopies (EGD) is estimated to occur in 1 2000 procedures. It presumed, but not proven, that retained food (RF) the esophagus or stomach EGD a risk factor. Yet despite pre-procedural fasting residual gastric identified 3% of patients undergoing EGD. We aimed estimate events with RF EGD, and particular receiving monitored anesthetic care (MAC) general anesthesia (GA). Methods: Electronic medical record systems were used...