A5053002822- Vaccine Coverage and Hesitancy
- Influenza Virus Research Studies
- Bacterial Infections and Vaccines
- Hepatitis Viruses Studies and Epidemiology
- HIV/AIDS Research and Interventions
- Travel-related health issues
- Antibiotics Pharmacokinetics and Efficacy
- COVID-19 Impact on Reproduction
- Antimicrobial Resistance in Staphylococcus
- Bacterial Identification and Susceptibility Testing
- Pregnancy and Medication Impact
- Liver Disease Diagnosis and Treatment
- Gestational Diabetes Research and Management
- Global Maternal and Child Health
- Respiratory viral infections research
- HIV, Drug Use, Sexual Risk
- Streptococcal Infections and Treatments
- Reproductive System and Pregnancy
- Pneumonia and Respiratory Infections
- Sepsis Diagnosis and Treatment
- Global Public Health Policies and Epidemiology
- Antibiotic Use and Resistance
- SARS-CoV-2 and COVID-19 Research
- Maternal and fetal healthcare
- Preterm Birth and Chorioamnionitis
Monash University
2016-2025
Monash Health
2016-2025
Royal Women's Hospital
2023-2024
Australian Regenerative Medicine Institute
2023
Monash Medical Centre
2023
Alice Springs Hospital
2016-2019
Northern Hospital
2018
The Alfred Hospital
2012
The role of maternal vaccination in reducing neonatal morbidity and mortality is expanding but uptake remains suboptimal. While the barriers to have been well described, women from minority groups not represented previous studies. In this study we examine facilitators antenatal by culturally linguistically diverse backgrounds Melbourne, Australia. 537 attending care completed a survey; 69% were born overseas. 63% had or intended receive pertussis vaccine 57% influenza during their pregnancy....
SUMMARY This study aimed to examine the epidemiology and treatment outcomes of community-onset purulent staphylococcal skin soft tissue infections (SSTI) in Central Australia. We performed a prospective observational patients hospitalised with SSTI ( n = 160). Indigenous accounted for 78% cases. Patients were predominantly young adults; however, there high rates co-morbid disease. Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) was dominant phenotype, accounting...
Excluding pregnant women with human immunodeficiency virus (HIV) from clinical trials results in inadequate pregnancy safety data for new antiretroviral therapies (ART). More rapid accumulation of ART is required. The Antiretroviral Pregnancy Registry (APR) collects teratogenicity on exposures during conception and pregnancy, yet reporting to the registry suboptimal, impacting choices HIV globally. This research assesses awareness APR barriers among providers United States (US) Australia....
<ns4:p>The vaccination of pregnant women has enormous potential to protect not only mothers from vaccine-preventable diseases but also their infants through the passive acquisition protective antibodies before they are able themselves acquire protection active childhood immunisations. Maternal tetanus programmes have been in place since 1989, and as March 2018, 14 countries world were still reach maternal neonatal elimination status. This saved hundreds thousands lives. Building on this...
There are no available pharmacokinetic data to guide piperacillin dosing in critically ill Australian Indigenous patients despite numerous reported physiological differences. This study aimed describe the population pharmacokinetics of with severe sepsis. A sepsis was conducted a remote hospital intensive care unit. Plasma samples were collected over two intervals and assayed by validated chromatography. Population modeling using Pmetrics. Nine recruited, two-compartment model adequately...
Vancomycin is a commonly used antibiotic due to the high burden of methicillin-resistant Staphylococcus aureus infections. This study aimed describe pharmacokinetics (PK) vancomycin in Australian Indigenous patients with severe sepsis, and advise an optimal dosing strategy. A population PK was conducted remote intensive care unit (ICU). Serial plasma samples were collected over one two intervals assayed by validated chromatography. Concentration–time data analysed using Pmetrics® software....
Abstract Background Infective endocarditis (IE) results in substantial morbidity and mortality people who inject drugs (PWID). Aims To describe the burden of IE its outcomes PWID. Methods Retrospective cohort study adults admitted to a tertiary referral centre Melbourne, Australia, with due injection drug use from 1997 2015. Results Ninety‐seven PWID 127 episodes were identified median acute inpatient stay 37 days (1–84). Admission an intensive care unit was required 67/127 (53%) episodes....
Women comprise a minority population of individuals living with HIV in Australia, and are often poorly represented research clinical trials so their needs remain largely unknown. Data suggests that they diagnosed later than men start antiretroviral therapy at lower CD4 cell count. This raises the question whether there sex specific barriers to linkage retention care. study analyzed 484 surveys received from clinicians collecting demographic, virological, reproductive health data along...
Travel during pregnancy is common, but associated with a number of risks and potential problems. There are many pregnancy‐specific destination‐specific issues to be considered along related method transport. experiences should made as safe possible through evidence‐based counselling via healthcare providers prior travel. This travelling in article has been created facilitate having these pre‐travel discussions optimise maternal fetal wellbeing.
Background Travel poses risks to pregnant women, but little data exist describing the travel habits of women during pregnancy or pre‐travel recommendations given. Aims To examine patterns including frequency consultation, and advice recalled. Materials Methods Cross‐sectional analysis post‐partum admitted five Victorian maternity hospitals between 21 May 2019 22 April 2020 in Australia. Results Forty‐four percent (182/410) travelled pregnancy, 32.9% (135/410) interstate 19.5% (80/410)...
Background Women's decisions regarding vaccination during pregnancy are heavily influenced by maternity care provider ( MCP ) recommendations. Understanding why s may not recommend is central to improving rates. Aims To examine the knowledge, attitudes and practice of Australian maternal vaccination. Methods We surveyed obstetricians, midwives general practitioners GP s) between September November 2016. Providers were asked about their knowledge current practice, perceived roles in...
Maternal immunisation is an essential public health intervention aimed at improving the outcomes for pregnant women and providing protection to newborn. Despite international recommendations, safety efficacy data intervention, often a fully funded program, uptake of vaccines in pregnancy remain suboptimal. One possible explanation this includes limited access vaccination services point antenatal care. The aim study evaluate change vaccine coverage among following implementation modified...
Since its discovery in late 2019, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been estimated to be responsible for at least 769.3 million infections and over 6.95 deaths. Despite significant global vaccination efforts, there are limited therapies that considered safe effective use management of COVID-19 during pregnancy despite common knowledge pregnant patients have a much higher risk adverse outcomes. A bioactive compound found broccoli sprout—sulforaphane—is...