Christine Köppl

ORCID: 0000-0003-0729-709X
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About
Contact & Profiles
Research Areas
  • Hearing, Cochlea, Tinnitus, Genetics
  • Animal Vocal Communication and Behavior
  • Marine animal studies overview
  • Hearing Loss and Rehabilitation
  • Bat Biology and Ecology Studies
  • Neural dynamics and brain function
  • Vestibular and auditory disorders
  • Noise Effects and Management
  • Animal Behavior and Reproduction
  • Amphibian and Reptile Biology
  • Neurobiology and Insect Physiology Research
  • Animal Nutrition and Physiology
  • Neuroscience and Neural Engineering
  • Acoustic Wave Phenomena Research
  • Insect and Arachnid Ecology and Behavior
  • Evolution and Paleontology Studies
  • Olfactory and Sensory Function Studies
  • Neuroscience and Music Perception
  • Biochemical Analysis and Sensing Techniques
  • Primate Behavior and Ecology
  • Multisensory perception and integration
  • Photoreceptor and optogenetics research
  • Vector-borne infectious diseases
  • Ichthyology and Marine Biology
  • Animal Behavior and Welfare Studies

Carl von Ossietzky Universität Oldenburg
2015-2025

Hearing4all
2015-2025

US Forest Service
2024

Google (United States)
2017

The University of Sydney
2007-2009

Technical University of Munich
1998-2008

The University of Western Australia
1994-2004

Ludwig-Maximilians-Universität München
1995-1998

University of Birmingham
1989

The auditory system of the barn owl is an important model for temporal processing on a very fast time scale and neural mechanisms circuitry underlying sound localization. Phase locking has been shown to be behaviorally relevant code. This study examined quality intensity dependence phase in single nerve fibers define input known brainstem circuit processing. For direct comparison same individuals, recordings were also obtained from next higher center, nucleus magnocellularis (NM). was...

10.1523/jneurosci.17-09-03312.1997 article EN cc-by-nc-sa Journal of Neuroscience 1997-05-01

The nucleus ventralis lemnisci lateralis pars posterior (VLVp) is the first binaural station in intensity-processing pathway of barn owl. Contralateral stimulation excites and ipsilateral inhibits VLVp cells. strength inhibition declines systematically from dorsal to ventral within nucleus. Cells selective for different intensity disparities occur an orderly sequence each isofrequency lamina. at intermediate depths are a particular narrow range interaural differences independently absolute...

10.1523/jneurosci.08-08-02665.1988 article EN cc-by-nc-sa Journal of Neuroscience 1988-08-01

In mammalian hearing, type-I afferent auditory nerve fibers comprise the basis of pathway. They are connected to inner hair cells cochlea via specialized ribbon synapses. Auditory different physiological types differ subtly in their synaptic location and morphology. Low-spontaneous-rate typically connect on modiolar side cell, while high-spontaneous-rate found pillar side. aging noise-damaged ears, this fine-tuned balance between fiber populations can be disrupted functional consequences...

10.3390/ijms25052738 article EN International Journal of Molecular Sciences 2024-02-27

Köppl, Christine. Frequency tuning and spontaneous activity in the auditory nerve cochlear nucleus magnocellularis of barn owl Tyto alba. J. Neurophysiol. 77: 364–377, 1997. Single-unit recordings were obtained from brain stem at level entrance nerve. Auditory units distinguished by physiological criteria, with use response latency to clicks, discharge rate, pattern characteristic frequencies encountered along an electrode track. The click stimulation decreased a logarithmic fashion...

10.1152/jn.1997.77.1.364 article EN Journal of Neurophysiology 1997-01-01

Vertebrate sensory hair cells achieve high sensitivity and frequency selectivity by adding self-generated mechanical energy to low-level signals. This allows them detect signals that are smaller than thermal molecular motion significant resonance amplitudes despite the viscosity of surrounding fluid. In nonmammals, a great deal in vitro evidence indicates active process responsible for this amplification is intimately associated with cells' transduction channels stereovillar bundle. Here, we...

10.1073/pnas.041604998 article EN Proceedings of the National Academy of Sciences 2001-02-13

Species with extensive geographical ranges pose special challenges to assessing drivers of wildlife disease, necessitating collaborative and large-scale analyses. The imperilled foothill yellow-legged frog ( Rana boylii ) inhabits a wide range variable conditions in rivers California Oregon (USA), is considered threatened by the pathogen Batrachochytrium dendrobatidis (Bd). To assess Bd infections over time space, we compiled 2000 datapoints from R. museum specimens (collected 1897–2005)...

10.1098/rsos.231270 article EN cc-by Royal Society Open Science 2024-01-01

Age-related hearing loss is a complex phenomenon. The earliest-onset degenerative event the gradual of neural connections between cochlea and auditory brainstem. To probe for perceptual deficits that might arise from this loss, cochlear synaptopathy was induced pharmacologically in young-adult gerbils which were then tested challenging listening task perception temporal fine structure. Treated behaved no differently than normal-hearing, animals. In contrast, old gerbils, typically express...

10.7554/elife.102890 preprint EN 2025-01-22

Age-related hearing loss is a complex phenomenon. The earliest-onset degenerative event the gradual of neural connections between cochlea and auditory brainstem. To probe for perceptual deficits that might arise from this loss, cochlear synaptopathy was induced pharmacologically in young-adult gerbils which were then tested challenging listening task perception temporal fine structure. Treated behaved no differently than normal-hearing, animals. In contrast, old gerbils, typically express...

10.7554/elife.102890.1 preprint EN 2025-01-22

People suffering from age-related hearing loss typically present with deficits in temporal processing tasks. Temporal have also been shown single-unit studies at the level of auditory brainstem, midbrain, and cortex aged animals. In this study, we explored whether coding is already affected input to central system. Single-unit nerve fiber recordings were obtained 41 Mongolian gerbils either sex, divided between young, middle-aged, old gerbils. quality was evaluated as vector strength...

10.1523/jneurosci.2784-18.2019 article EN cc-by-nc-sa Journal of Neuroscience 2019-11-12

Age-related hearing loss (HL), or presbycusis, is a complex and heterogeneous condition, affecting significant portion of older adults involving various interacting mechanisms. Metabolic type age-related HL, characterized by the dysfunction stria vascularis, which crucial for maintaining endocochlear potential necessary hearing. Although attention on metabolic presbycusis has waned in recent years, research continues to identify strial pathology as key factor HL. This narrative review...

10.3390/ijms25105391 article EN International Journal of Molecular Sciences 2024-05-15

The cochlear nucleus angularis (NA) is widely assumed to form the starting point of a brain stem pathway for processing sound intensity in birds. Details its function are unclear, however, and evolutionary origin relationship mammalian cochlear-nucleus complex obscure. We have carried out extracellular single-unit recordings NA ketamine-anesthetized barn owls. aim was re-evaluate extent heterogeneity physiology because recent studies cellular morphology had established several distinct...

10.1152/jn.00635.2002 article EN Journal of Neurophysiology 2003-04-01

10.1016/j.cub.2009.05.035 article EN publisher-specific-oa Current Biology 2009-08-01
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