Ivana Garcarova

ORCID: 0000-0003-0756-9788
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About
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Research Areas
  • Nanocluster Synthesis and Applications
  • Advanced Nanomaterials in Catalysis
  • Alzheimer's disease research and treatments
  • Nanoparticles: synthesis and applications
  • Computational Drug Discovery Methods
  • Carbon and Quantum Dots Applications
  • Electrochemical sensors and biosensors
  • Cholinesterase and Neurodegenerative Diseases

Slovak Academy of Sciences
2021-2023

Institute of Experimental Physics of the Slovak Academy of Sciences
2021-2023

Cerium oxide nanoparticles (CeO2 NPs) are well known for their application in various fields of industry, as biology and medicine. Knowledge synthesis schemes, physicochemical morphological features nanoscale CeO2 is important assessing antioxidant behavior understanding the mechanism oxidative stress its consequences. The choice method should be based on possibility to choose conditions parameters obtaining with controlled dimensions a ratio Се3+/Се4+ surface. In this study, NPs synthesized...

10.1016/j.colsurfb.2022.112960 article EN cc-by-nc-nd Colloids and Surfaces B Biointerfaces 2022-10-22

Abstract A set of cerium dioxide nanoparticles (CeO 2 NPs) was synthesized by precipitation in water-alcohol solutions under conditions when the physical-chemical parameters NPs were controlled changing ratio reaction components. The size CeO is largely dielectric constant solution. An increase percentage Ce 3+ ions at surface observed with a concomitant reduction NP sizes. All possess relatively high positive values zeta-potential ( ζ > 40 mV) suggesting good stability aqueous...

10.1088/1361-6528/abf7e9 article EN Nanotechnology 2021-04-15

Oxidative stress is known to be associated with a number of degenerative diseases. A better knowledge the interplay between oxidative and amyloidogenesis crucial for understanding both, aging age-related neurodegenerative Cerium dioxide nanoparticles (CeO2 NPs, nanoceria) due their remarkable properties are perspective nanomaterials in study processes accompanying oxidative-stress-related diseases, including amyloid-related pathologies. In present work, we analyze effects CeO2 NPs different...

10.3390/biomedicines10050942 article EN cc-by Biomedicines 2022-04-19

"Core/shell" nanocomposites based on magnetic magnetite (Fe3O4) and redox-active cerium dioxide (CeO2) nanoparticles (NPs) are promising in the field of biomedical interests because they can combine ability NPs to heat up an alternating (AMF) with pronounced antioxidant activity CeO2 NPs. Thus, this report is devoted Fe3O4/CeO2 (NCPs) synthesized by precipitation computed amount "CeO2-shell" surface prefabricated Fe3O4 The X-ray diffraction, photoelectron spectroscopy, high-resolution...

10.1021/acsami.3c10845 article EN ACS Applied Materials & Interfaces 2023-10-12

The amyloidogenic self-assembly of many peptides and proteins largely depends on external conditions. Among amyloid-prone proteins, insulin attracts attention because its physiological therapeutic importance. In the present work, amyloid aggregation is studied in presence cholesterol-based detergent, Chobimalt. strategy to elucidate Chobimalt-induced effect fibrillogenesis based performing concentration- time-dependent analysis using a combination different experimental techniques, such as...

10.3389/fmolb.2022.955282 article EN cc-by Frontiers in Molecular Biosciences 2022-08-19
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