- Nanocluster Synthesis and Applications
- Advanced Nanomaterials in Catalysis
- Alzheimer's disease research and treatments
- Nanoparticles: synthesis and applications
- Computational Drug Discovery Methods
- Carbon and Quantum Dots Applications
- Electrochemical sensors and biosensors
- Cholinesterase and Neurodegenerative Diseases
Slovak Academy of Sciences
2021-2023
Institute of Experimental Physics of the Slovak Academy of Sciences
2021-2023
Cerium oxide nanoparticles (CeO2 NPs) are well known for their application in various fields of industry, as biology and medicine. Knowledge synthesis schemes, physicochemical morphological features nanoscale CeO2 is important assessing antioxidant behavior understanding the mechanism oxidative stress its consequences. The choice method should be based on possibility to choose conditions parameters obtaining with controlled dimensions a ratio Се3+/Се4+ surface. In this study, NPs synthesized...
Abstract A set of cerium dioxide nanoparticles (CeO 2 NPs) was synthesized by precipitation in water-alcohol solutions under conditions when the physical-chemical parameters NPs were controlled changing ratio reaction components. The size CeO is largely dielectric constant solution. An increase percentage Ce 3+ ions at surface observed with a concomitant reduction NP sizes. All possess relatively high positive values zeta-potential ( ζ > 40 mV) suggesting good stability aqueous...
Oxidative stress is known to be associated with a number of degenerative diseases. A better knowledge the interplay between oxidative and amyloidogenesis crucial for understanding both, aging age-related neurodegenerative Cerium dioxide nanoparticles (CeO2 NPs, nanoceria) due their remarkable properties are perspective nanomaterials in study processes accompanying oxidative-stress-related diseases, including amyloid-related pathologies. In present work, we analyze effects CeO2 NPs different...
"Core/shell" nanocomposites based on magnetic magnetite (Fe3O4) and redox-active cerium dioxide (CeO2) nanoparticles (NPs) are promising in the field of biomedical interests because they can combine ability NPs to heat up an alternating (AMF) with pronounced antioxidant activity CeO2 NPs. Thus, this report is devoted Fe3O4/CeO2 (NCPs) synthesized by precipitation computed amount "CeO2-shell" surface prefabricated Fe3O4 The X-ray diffraction, photoelectron spectroscopy, high-resolution...
The amyloidogenic self-assembly of many peptides and proteins largely depends on external conditions. Among amyloid-prone proteins, insulin attracts attention because its physiological therapeutic importance. In the present work, amyloid aggregation is studied in presence cholesterol-based detergent, Chobimalt. strategy to elucidate Chobimalt-induced effect fibrillogenesis based performing concentration- time-dependent analysis using a combination different experimental techniques, such as...