A5035520691- Glioma Diagnosis and Treatment
- Ear Surgery and Otitis Media
- Hearing, Cochlea, Tinnitus, Genetics
- Head and Neck Anomalies
- Hearing Loss and Rehabilitation
- Head and Neck Surgical Oncology
- Vestibular and auditory disorders
- Spinal Dysraphism and Malformations
- Spinal Fractures and Fixation Techniques
- Neonatal and fetal brain pathology
- Tumors and Oncological Cases
- Fetal and Pediatric Neurological Disorders
- Congenital Ear and Nasal Anomalies
- Meningioma and schwannoma management
- Traumatic Brain Injury and Neurovascular Disturbances
- Child Abuse and Related Trauma
- Cerebral Venous Sinus Thrombosis
- Teratomas and Epidermoid Cysts
- Neuroblastoma Research and Treatments
- Pelvic and Acetabular Injuries
- Traumatic Ocular and Foreign Body Injuries
- Vascular Malformations Diagnosis and Treatment
- Trauma Management and Diagnosis
- Radiation Therapy and Dosimetry
- Boron Compounds in Chemistry
The University of Texas Southwestern Medical Center
2015-2024
Southwestern Medical Center
2010-2023
Harold C. Simmons Comprehensive Cancer Center
2020-2021
Children's Medical Center
2004-2020
Children's Oncology Group
2012-2020
University of Calgary
2020
University of Southern California
2020
University of California, San Francisco
2020
Hospital for Sick Children
2020
Neurological Surgery
2019
PURPOSE Surgery is curative therapy for pediatric low-grade gliomas (LGGs) in areas of the brain amenable to complete resection. However, LGGs located where resection not possible can threaten both function and life. The purpose this study was compare two chemotherapy regimens children younger than age 10 years whom radiotherapy felt by practitioner pose a high risk neurodevelopmental injury. PATIENTS AND METHODS Previously untreated with progressive or residual were eligible. Children...
Atypical teratoid/rhabdoid tumor (AT/RT) is an aggressive, early-childhood brain without standard effective treatment. To our knowledge, we conducted the first AT/RT-specific cooperative group trial, ACNS0333, to examine efficacy and safety of intensive postoperative chemotherapy focal radiation treat AT/RT.Patients from birth 22 years age with AT/RT were eligible. After surgery, they received 2 courses multiagent chemotherapy, followed by 3 high-dose peripheral blood stem cell rescue...
Children with average-risk medulloblastoma (MB) experience survival rates of ≥ 80% at the expense adverse consequences treatment. Efforts to mitigate these effects include deintensification craniospinal irradiation (CSI) dose and volume.ACNS0331 (ClinicalTrials.gov identifier: NCT00085735) randomly assigned patients age 3-21 years MB receive posterior fossa radiation therapy (PFRT) or involved field (IFRT) following CSI. Young children (3-7 years) were also standard-dose CSI (SDCSI; 23.4 Gy)...
<h3>Objective</h3> To evaluate the incidence and type of intracranial inner ear abnormalities in children with sensorineural hearing loss (SNHL) identified magnetic resonance imaging (MRI) stratified by degree SNHL. <h3>Design</h3> Retrospective review medical records MRIs. <h3>Setting</h3> Tertiary care children's hospital. <h3>Patients</h3> A total 227 aged 1 month to 17 years (mean age, 5.3 years; male female ratio, 1:1) a diagnosis SNHL underwent MRI from June 1,1996, 1, 2002. Of these...
BACKGROUND To evaluate tumor responses, event‐free survival (EFS), overall (OS), and toxicity of chemotherapy, children with neurofibromatosis type 1 (NF1) progressive low‐grade glioma were enrolled into the Children's Oncology Group (COG) A9952 protocol treated carboplatin vincristine (CV). METHODS Non‐NF1 patients randomized to CV or thioguanine, procarbazine, 1‐(2‐chloroethyl)‐3‐cyclohexyl‐1‐nitrosourea, in COG A9952. NF1 assigned only. non‐NF1 who compared respect baseline...
Objectives: To compare magnetic resonance imaging (MRI) to high-resolution computed tomography (HRCT) in the preoperative evaluation of pediatric cochlear implant candidates. Methods: The charts candidates evaluated between July 1, 2000 and November 30, 2003 with an MRI scan inner ear were included study. Fifty-six patients included. Associated HRCT scans examined. Abnormalities cochlea, nerve, endolymphatic sac, duct, vestibule, modiolus noted. A neuroradiologist gave opinion as whether...
Objective: To evaluate speech perception after cochlear implantation in children with nerve absence or deficiency. Methods: A retrospective case review was performed to identify who underwent The evaluated by high-resolution three-dimensional T2-weighted fast spin echo MR the oblique sagittal and axial planes. deficient defined as a that is smaller diameter when compared adjacent facial midportion of internal auditory canal. considered absent if there no imaging evidence nerve. Speech...
To determine the accuracy of preoperative MRI in predicting cochlear obstruction pediatric patients with a history bacterial meningitis.A case series chart review was performed at tertiary care multidisciplinary implant program. Forty-five children hearing loss that resulted from meningitis were implanted 1991 to 2006. Twenty-five had high-resolution axial T2-weighted images assess for patency.Seventeen 25 (68%) surgical evidence obstruction. Six (37.5%) required circummodiolar drill-outs,...
Herman, Martin J. MD; Brown, Kristin O. MS; Sponseller, Paul D. Phillips, Jonathan H. Petrucelli, Philip M. Parikh, Darshan BS; Mody, Kush S. Leonard, Julie C. MD, MPH; Moront, Matthew Brockmeyer, Douglas L. Anderson, Richard C.E. Alder, Adam John T. Bernstein, Robert Booth, Timothy N. Braga, Bruno P. Cahill, Patrick Joglar, Jeanne Martus, Jeffrey E. Nesiama, Jo-Ann Pahys, Joshua Rathjen, Karl Riccio, Anthony I. Schulz, Jacob F. Stans, A. Shah, Manish Warner, William Jr. Yaszay, Burt MD...
<h3>BACKGROUND AND PURPOSE:</h3> Cervical MR imaging has demonstrated a utility for detecting soft tissue injury in nonaccidental trauma. The purpose of this study was to identify the incidence and types cervical spine on trauma correlate with parenchymal brain findings head CT. <h3>MATERIALS METHODS:</h3> A retrospective review children diagnosed tertiary referral pediatric hospital over 8 years performed. Inclusion criteria were younger than 5 age, confirmed diagnosis trauma, within 1 week...
To review our experience with foregut duplication cysts of the anterior tongue, an unusual and rarely encountered mass in this location.A retrospective patients tongue identified between 1990 2000.Academic, tertiary care children's medical center.Six pediatric (5 boys 1 girl) ranging age from birth to 8 months at diagnosis.Three underwent preoperative magnetic resonance imaging (MRI). All 6 excisional biopsy.Clinical description cysts, ability make diagnosis preoperatively, recurrence...
Chronic venous hypertension due to jugular foramen stenosis has been proposed as an etiology for the hydrocephalus and tonsillar herniation seen in some patients with complex craniosynostosis. We report use of MR venography (MRV) evaluate outflow obstruction this clinical setting.We studied 17 patients, (ages 4 months 34 years; mean 7.3 years) craniosynostosis; 8 Crouzon's syndrome, 2 Apert's, 1 Pfeiffer's 6 without eponymous classification. imaging included routine sequences axial 2D TOF...
Nonperioperative strokes are rare yet potentially devastating events for children with central nervous system (CNS) tumors. The incidence of and risk factors nonperioperative in CNS tumors is unknown.The authors performed a retrospective review from their institution stroke the period influence patient demographic factors, coexisting genetic diseases, tumor type, treatment modality on subsequent occurrence were determined.Eight hundred seven consecutive patients authors' observed combined...