A5103128397- Antibiotic Use and Resistance
- Immune Cell Function and Interaction
- Bacterial Identification and Susceptibility Testing
- Patient Satisfaction in Healthcare
- Sepsis Diagnosis and Treatment
- Reproductive System and Pregnancy
- Infection Control and Ventilation
- T-cell and Retrovirus Studies
- Streptococcal Infections and Treatments
- Cardiovascular Issues in Pregnancy
- Pneumonia and Respiratory Infections
- Renal Transplantation Outcomes and Treatments
- Venous Thromboembolism Diagnosis and Management
- Non-Invasive Vital Sign Monitoring
- Context-Aware Activity Recognition Systems
- Heart Failure Treatment and Management
- Animal Disease Management and Epidemiology
- Immune Response and Inflammation
- Healthcare Technology and Patient Monitoring
- Folate and B Vitamins Research
- Digital Imaging in Medicine
- Nosocomial Infections in ICU
- Acute Lymphoblastic Leukemia research
- T-cell and B-cell Immunology
- Connective tissue disorders research
Tel Aviv Sourasky Medical Center
2023-2025
Tel Aviv University
2022
Ben-Gurion University of the Negev
2019-2021
Weill Cornell Medicine
2016-2018
Cornell University
2016-2018
Stanford University
1986-2018
University of Alabama at Birmingham
2018
Columbia University
2018
University of Pittsburgh
2018
Vanderbilt University
2018
Functional analyses of peripheral blood leukocytes (PBL) from high risk HTLV-III antibody-negative and antibody-positive donors, as well patients with acquired immune deficiency syndrome (AIDS), lymphadenopathy (LAS), AIDS-related complex (ARC) were performed by the in vitro generation cytotoxic T lymphocyte (CTL) proliferative responses to HLA self-restricted antigens influenza virus (S + X) nonself restricted alloantigens (ALLO). All 40 donors tested responded both S X ALLO CTL response,...
• To clarify the epidemiology of pulmonary embolism in adolescents, a retrospective analysis adolescent admissions to general hospital over 15-year period was performed. Eighteen patients had 19 episodes embolism, an incidence 78 per 100 000 hospitalized adolescents. There were twice as many female male patients. Common complaints chest pain, dyspnea, cough, and hemoptysis. findings hypoxemia deep-vein thrombosis. Major risk factors oral contraceptive use elective abortion 75% trauma 67%...
OBJECTIVE To assess antimicrobial prescriber knowledge, attitudes, and practices (KAP) regarding stewardship (AS) associated barriers to optimal prescribing. DESIGN Cross-sectional survey. SETTING Online PARTICIPANTS A convenience sample of 2,900 US prescribers at 5 acute-care hospitals within a hospital network. INTERVENTION The following characteristics were assessed with an anonymous, online survey in February 2015: attitudes related resistance, AS programs, institutional resources;...
Peripheral blood leukocytes (PBL) from 18 homosexual men who did not have acquired immunodeficiency syndrome (AIDS) and 9 heterosexual were repetitively tested for their ability to generate HLA self-restricted cytotoxic T lymphocyte responses influenza virus (flu-self) over a 2-yr period. The sera of the same donors antibodies human lymphotropic virus-III (HTLV-III). Six none consistently generated weak flu-self. Seven seropositive HTLV-III. No obvious correlation was detected between...
Antimicrobial resistance is a rising global health threat, leading to ineffective treatments, increased mortality and healthcare costs. In ICUs, inappropriate empiric antibiotic therapy often given due treatment urgency, causing poor outcomes. This study developed machine learning model predict the appropriateness of antibiotics for ICU-acquired bloodstream infections, using data from MIMIC-III database. To address missing values dataset imbalances, novel computational methods were...
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To assess the utility of C-reactive protein (CRP) velocity to discriminate between patients with acute viral and bacterial infections who presented relatively low CRP concentrations were suspected having a infection.We analyzed retrospective cohort emergency department (ED) first measurement (CRP1) ≤ 31.9 mg/L received antibiotics shortly after. We then calculated (CRPv), milligram per liter hour, for each patient based on CRP1 second value (CRP2) measured within 24 h since admission....
Peripheral blood leukocytes (PBL) from male homosexual and heterosexual volunteers who did not have evidence of acquired immunodeficiency syndrome (AIDS) were studied for their ability to generate cytotoxic T lymphocyte (CTL) responses in vitro allogeneic stimulator PBL a single individual or pool donors (allo-pool). Seventeen 39 generated strong primary CTL activity randomly selected donor, whereas only two 16 response the same stimulators. A more detailed study was performed by using 11...
The correlation between ATP concentration and bacterial burden in the patient care environment was assessed. These findings suggest that a exists burden, they generally support technology manufacturer-recommended cutoff values. Despite relatively modest discriminative ability, this may serve as useful proxy for cleanliness. Infect Control Hosp Epidemiol 2018;39:622–624
We have developed a patient triage and monitoring system to facilitate effectiveness care during emergency medical situations. This includes: 1) electronic tags, 2) location sensors, 3) vital sign 4) robust ad-hoc mesh networking software. paper summarizes our development of continuous, automated, real-time biomedical sensors software for use by responders chaotic pre-hospital settings.
OBJECTIVES Bone marrow suppression is a common adverse effect of the immunosuppressive drug azathioprine. Polymorphisms in gene encoding thiopurine S-methyltransferase (TPMT) can alter metabolism azathioprine, resulting toxicity and life-threatening infection. In multicenter cohort pediatric heart transplant (HT) recipients, we determined frequency TPMT genetic variation assessed whether azathioprine-treated recipients with variants were at increased risk METHODS We genotyped 264 HT for...
The in vitro generation of allospecific CTL by human PBMC was enhanced 4- to 16-fold sequential plastic and nylon wool adherence, which depleted the macrophages B cells. response suppressed adding back irradiated, unfractionated or adherent cells This finding suggests that not simply a consequence enrichment T cells, but instead due active suppression radioresistant contained fraction. Of note is that, unlike response, proliferative allostimulation affected removal suppressor function could...
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Abstract Antimicrobial resistance is a growing threat to global health, leading ineffective treatment of infection and increasing failure, mortality, healthcare costs. Inappropriate antibiotic therapy often administered in the Intensive Care Unit (ICU) due urgency treatment, but can lead poor patient outcomes. In this study, we developed machine learning model that predicts appropriateness treatments for ICU inpatients with ICU-acquired blood infection. We analyzed data from electronic...
Abstract Background Albumin (ALB) is a known biomarker of frailty, and cardiovascular disease frailty are interdependent. Epidemiological evidence demonstrates that low serum albumin levels linked to events ischemic heart (IHD), venous thromboembolism, failure, atrial fibrillation, stroke. Purpose We aimed investigate the association variations in ALB within normal range with IHD among apparently healthy adults. Methods A case-control retrospective study self-referred adults participating an...