A5058364553- Heavy Metal Exposure and Toxicity
- Arsenic contamination and mitigation
- Nitric Oxide and Endothelin Effects
- Contact Dermatitis and Allergies
- Renin-Angiotensin System Studies
- Effects and risks of endocrine disrupting chemicals
- Air Quality and Health Impacts
- Climate Change and Health Impacts
- Electrochemical Analysis and Applications
- Pelvic and Acetabular Injuries
- HIV-related health complications and treatments
- Cardiovascular Issues in Pregnancy
- Pneumocystis jirovecii pneumonia detection and treatment
- Spinal Fractures and Fixation Techniques
- Spine and Intervertebral Disc Pathology
- Birth, Development, and Health
- Redox biology and oxidative stress
- Cardiac Arrest and Resuscitation
- Cardiac Ischemia and Reperfusion
- Antimicrobial agents and applications
- Bone and Joint Diseases
SUNY Downstate Health Sciences University
2020-2023
State University of New York
2023
NuVasive (United States)
2022
Medtronic (Ireland)
2022
Stryker (United States)
2022
Orthofix (United States)
2022
Zimmer Biomet (Switzerland)
2022
Globus Medical (United States)
2022
Medtronic (United States)
2022
Zimmer Biomet (United States)
2022
Protein S-nitros(yl)ation (SNO) has been implicated as an essential mediator of nitric oxide-dependent cardioprotection. Compared with males, female hearts exhibit higher baseline levels protein SNO and associated this, reduced susceptibility to myocardial ischemia-reperfusion injury. Female also enhanced S-nitrosoglutathione reductase (GSNO-R) activity, which would typically favor decreased GSNO-R mediates catabolism. Because levels, we hypothesized that is component sex-dependent...
Arsenic is a common contaminant in drinking water throughout the world, and recent studies support link between inorganic arsenic (iAS) exposure ischemic heart disease men women. Female hearts exhibit an estrogen-dependent reduction susceptibility to myocardial injury compared with males, as such, female may be more susceptible endocrine-disrupting effects of iAS exposure. However, have not been examined mechanistic studies. Male mice (8 wk) were exposed environmentally relevant...
In the United States, nearly 1.2 million people > 12 years old have human immunodeficiency virus (HIV), which is associated with postoperative complications following orthopedic procedures. Little known about how asymptomatic HIV (AHIV) patients fare postoperatively. This study compares after common spine surgeries between and without AHIV. The Nationwide Inpatient Sample (NIS) was retrospectively reviewed from 2005-2013, identifying aged 18 who underwent 2-3-level anterior cervical...
Abstract Triclosan is a broad-spectrum antimicrobial agent used in multitude of healthcare and consumer products. Epidemiological studies link triclosan exposure to several adverse health outcomes including alterations thyroid function an increased risk for allergies asthma suggesting immunomodulatory role the endocrine disrupting synthetic chemical. The effects on human immune system, particularly levels white blood cells, have yet be fully characterized. Using cross-sectional data from...
Osteoporosis affects nearly 200 million individuals worldwide. Given this notable disease burden, there have been increased efforts to investigate complications in patients with osteoporosis undergoing cervical fusion (CF). However, are limited data regarding long-term outcomes osteoporotic the setting of ≥4-level fusion.The New York State Statewide Planning and Research Cooperative System database was used identify who underwent posterior or combined anterior-posterior CF for radiculopathy...
Reversible forms of cysteine oxidation, including protein S ‐nitrosation (SNO), have been implicated as essential mediators nitric oxide‐dependent cardioprotection. Compared to males, female hearts exhibit higher baseline levels SNO, and associated with this, reduced susceptibility myocardial ischemia‐reperfusion (I/R) injury. Female also enhanced ‐nitrosoglutathione reductase (GSNOR) activity, which typically favors decreased SNO since GSNOR is a major mediator catabolism. Since levels, we...