A5015847576- Liver Disease Diagnosis and Treatment
- Hepatitis C virus research
- Hepatitis B Virus Studies
- Nutrition and Health in Aging
- Liver Disease and Transplantation
- Diet, Metabolism, and Disease
- Medical Device Sterilization and Disinfection
- Ethics in Clinical Research
- Healthcare and Environmental Waste Management
- Alcohol Consumption and Health Effects
- Liver Diseases and Immunity
- Systemic Lupus Erythematosus Research
- Clinical Nutrition and Gastroenterology
- Psoriasis: Treatment and Pathogenesis
Mahidol University
2021-2025
Siriraj Hospital
2016-2025
The clinical significance of steatohepatitis in chronic hepatitis B remains unclear. This study aimed to determine the prevalence and risk factors for B, its correlation with liver fibrosis response antiviral therapy.Liver histopathology 256 consecutive patients serum virus DNA >2000 IU/mL were analysed laboratory characteristics. Virological biochemical responses prospectively assessed 112 treated monotherapy.Hepatic steatosis was observed 38% entire cohort, diagnosed 18% hepatic according...
This randomized trial aimed to compare the effects of moderate-intensity aerobic vs resistance exercise with dietary modification in patients nonalcoholic fatty liver disease (NAFLD).Patients NAFLD were randomly assigned (1:1) a 12-week supervised training program or intervention consisting monthly individual nutritional counseling by dietician. Transient elastography, anthropometry, body composition, cardiorespiratory fitness, biochemistries, and glucose tolerance measured at baseline 12...
Physical inactivity and sarcopenia are two important predictors associated with increased morbidity mortality in patients cirrhosis. At present, the benefit of a home-based exercise training program is not well established cirrhotic patients. The main objective this study was to evaluate effect 12-week on aerobic capacity patients.This randomized controlled study. Patients compensated cirrhosis were by block 4 concealed allocation (n = 20) or control 20). Both groups received protein...
Sarcopenia, characterized by loss of muscle mass and function, has gained importance in the evaluation cirrhotic patients. Evidence suggests its role adverse clinical outcomes, including minimal hepatic encephalopathy (MHE). This study aimed to investigate association between sarcopenia MHE patients with cirrhosis. We prospectively enrolled outpatients cirrhosis assess using 2019 criteria from Asian Working Group for Sarcopenia. was diagnosed through Psychometric Hepatic Encephalopathy...
Dietary modification is essential for treating nonalcoholic fatty liver disease (NAFLD); however, the dietary components are less well defined. We enrolled 252 adults with no history of and excessive alcohol use to evaluate relationship between macronutrients NAFLD insulin resistance. Participants took photographs their meals documented food intake in a diary seven consecutive days. A dietitian estimated type portion size items analyzed nutrients INMUCAL-Nutrients software. Later,...
Aim To evaluate the utility of combination alanine aminotransferase (ALT) course, hepatitis B virus (HBV) DNA level, and liver stiffness measurement (LSM) for determining significant disease in e antigen (HBeAg)‐negative patients. Methods Three hundred ninety nine consecutive HBeAg‐negative patients with HBV >2000 IU/mL documented serial measurements ALT were enrolled to undergo LSM followed by biopsy. Results Using <40 IU/L as a normal value, 142 had persistently (PNALT), whereas 257...
Abstract Background and Aims The heritability of nonalcoholic fatty liver disease (NAFLD) in lean individuals is undetermined. This familial aggregation study aimed to evaluate linkage for NAFLD the risk among first‐degree relatives probands with NAFLD. Methods prospectively recruited cohorts NAFLD, obese non‐NAFLD their respective relatives. A total 257 participants were evaluated steatosis, defined by controlled attenuation parameter ≥288 dB/m 2 , metabolic characteristics, PNPLA3, TM6SF2,...
Abstract Background There is an urgent need for noninvasive tests to identify patients with psoriasis at risk of significant liver fibrosis. Objectives To externally validate the ability Steatosis-Associated Fibrosis Estimator (SAFE) score detect fibrosis in using transient elastography (TE) as a reference. Methods We analysed data from 75 psoriasis, including TE, SAFE score, Fibrosis-4 Index (FIB-4) and Nonalcoholic Fatty Liver Disease Score (NFS). Significant was defined TE values ≥ 7.1...
Journal Article Corrected proof Blood-based scoring systems for identifying significant liver fibrosis in patients with psoriasis Get access Leena Chularojanamontri, Chularojanamontri Conceptualization, Formal analysis, Investigation, Methodology, Writing - original draft, review & editing Department of Dermatology https://orcid.org/0000-0001-6625-6445 Search other works by this author on: Oxford Academic Google Scholar Waratchaya Panjapakkul, Panjapakkul draft...