- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Cardiac pacing and defibrillation studies
- Atrial Fibrillation Management and Outcomes
- ECG Monitoring and Analysis
- Cardiovascular Syncope and Autonomic Disorders
- Ion channel regulation and function
- Receptor Mechanisms and Signaling
- Cerebrovascular and Carotid Artery Diseases
- Cardiovascular Health and Disease Prevention
- Neuroscience and Neuropharmacology Research
- Cardiac Imaging and Diagnostics
- Advanced MRI Techniques and Applications
- Cardiovascular and Diving-Related Complications
- Anesthesia and Sedative Agents
- Heart Rate Variability and Autonomic Control
- Liver Disease Diagnosis and Treatment
- Acute Ischemic Stroke Management
- Phonocardiography and Auscultation Techniques
- Urticaria and Related Conditions
- Digital Mental Health Interventions
- Neurological and metabolic disorders
- Multisensory perception and integration
- History of Science and Natural History
- Heart rate and cardiovascular health
Humboldt-Universität zu Berlin
2023
Städtisches Klinikum Karlsruhe
2005
Cardiovascular Center Bethanien
2004
Kerckhoff Klinik
1991-2002
Goethe University Frankfurt
1989-2001
Max Planck Society
1991-2000
Institut für Medizinische Informatik, Biometrie und Epidemiologie
1998
Max Planck Institute for Heart and Lung Research
1991-1994
Georgetown University
1991
Nijmegen Institute for Scientist Practitioners in Addiction
1982-1989
In the present review paper by members of collaborative research center "Register: Language Users' Knowledge Situational-Functional Variation" (CRC 1412), we assess pervasiveness register phenomena across different time periods, languages, modalities, and cultures. We define "register" as recurring variation in language use depending on function social situation. Informed rich data, aim to better understand model knowledge involved situation- function-based register. order achieve this goal,...
GRÖNEFELD, G.C., et al. : Morphology Discrimination: A Beat‐to‐Beat Algorithm for the Discrimination of Ventricular From Supraventricular Tachycardia by Implantable Cardioverter Defibrillators. Inappropriate therapy SVTs ICDs remains a major clinical problem despite enhanced detection criteria like “sudden onset” and “rate stability” in third‐generation devices. Electrogram morphology discrimination offers an additional approach to improve supraventricular tachycardia (SVT) from ventricular...
The aim of the study was to compare defibrillation energy requirements and probability successful at multiples minimum in active pectoral implantable defibrillators with single- dual-coil lead systems. Eighty-three consecutive patients undergoing implantation an cardioverter-defibrillator were randomized receive a dual- or single-coil system. Defibrillators two manufacturers fixed tilt biphasic waveform used. Defibrillation determined using step-down testing protocol. According randomization...
CARLSSON, J., et al. : Myocardial Injury During Radiofrequency Catheter Ablation: Comparison of Focal and Linear Lesions. The aim study was to investigate the extent myocardial injury incurred by creation continuous RF current induced linear ablation lesions (LL; atrial fibrillation, right procedure) in comparison focal (FL; AV node reentry tachycardia, WPW tachycardia). In 23 patients with LL (age 51.3 ± 11.2 years, 18 men, 5 women) 16 FL 53.9 5.1 8 men women), levels creatine kinase (CK),...
Effects of AF-DX 116, a cardioselective antagonist, on M cholinergic receptors (M-ChR) were studied in healthy volunteers. Occupancy M-ChR subtypes by drug present plasma samples (radioreceptor assay) was compared with these effects. After an intravenous dose 116 saturating greater than 90% cardiac M2-ChR, increase heart rate 25 beats/min observed. This receptor occupancy and effect wore off parallel time course within 10 hours. No inhibition salivary flow observed, coinciding lack M3-ChR...
CARLSSON, J., et al. : Possible Role of Epicardial Left Ventricular Programmed Stimulation in Brugada Syndrome. A patient with recurrent syncope due to polymorphic ventricular tachcardia was diagnosed syndrome. right stimulation could not induce arrhythmia. from a left site through the coronary sinus led polymorhic VT. The protocol for risk stratification syndrome is discussed.
CARLSSON, J., et al .: Prospective Randomized Comparison of Two Defibrillation Safety Margins in Unipolar, Active Pectoral Defibrillator Therapy. Various techniques are used to establish defibrillation efficacy and evaluate safety margins patients with an ICD. In daily practice a margin 10 J is generally accepted. However, this based on old clinical data there no using current ICD technology unipolar, active pectoral defibrillators. Therefore, randomized study was performed test if the...
Abstract Aims Thermal injury of subendocardial tissue leads to a release electrolytes and free radicals from the intracellular site creating change in electrochemical potential (eP) between distal proximal catheter tip electrodes. The aim study was verify detection ablation-induced assess suitability control-line energy delivery at ablation by measuringeP . Methods Results In vitro tests under constant flow conditions were performed 10 l bath physiological saline solution or bovine blood....
AimsIn newer implantable cardioverter–defibrillators with automatic gain control amplifiers the maximum possible sensitivity is programmed aim of securing optimal detection ventricular fibrillation. This study was designed to prove that a reduction in safe respect appropriate sensing fibrillation, while avoiding extracardiac signals.