A5043995125- Amyotrophic Lateral Sclerosis Research
- Congenital heart defects research
- Congenital Heart Disease Studies
- Genetic Neurodegenerative Diseases
- Peripheral Neuropathies and Disorders
- Disaster Response and Management
- Inflammatory Myopathies and Dermatomyositis
- Neurogenetic and Muscular Disorders Research
- Neurological and metabolic disorders
- Vasculitis and related conditions
- Parkinson's Disease Mechanisms and Treatments
- Neurosurgical Procedures and Complications
- Muscle activation and electromyography studies
- Posttraumatic Stress Disorder Research
- Peripheral Nerve Disorders
- Chronic Lymphocytic Leukemia Research
- Obsessive-Compulsive Spectrum Disorders
- Autism Spectrum Disorder Research
- Digital Mental Health Interventions
- Coronary Artery Anomalies
- Healthcare Decision-Making and Restraints
- Homelessness and Social Issues
- Parasite Biology and Host Interactions
- Body Image and Dysmorphia Studies
- Cerebral Venous Sinus Thrombosis
Tokyo University of Science
2025
Tokyo Metropolitan Neurological Hospital
2017-2025
Daiyukai General Hospital
2021-2024
University of Tokyo Hospital
2022-2024
The University of Tokyo
2018-2023
The Health Care Science Institute
2021-2023
Tokyo Metropolitan Institute of Medical Science
2018-2023
Ludwig-Maximilians-Universität München
2023
Friedrich Baur Stiftung
2023
Kawamura Gakuen Women's University
2023
Problematic Internet use (PIU), hyperactivity/inattention, and depressive symptoms are comorbid problems in adolescence, but the causal relationships among these issues unclear. To assess PIU, adolescents general population. This longitudinal cohort study used data from Tokyo Teen Cohort Tokyo, Japan, for two years between October 2012 January 2015. Of 3171 pairs of children parents, 3007 continued to participate second wave study. A total were included analysis (mean [standard deviation]...
In Japan, the General Medicine In-training Examination (GM-ITE) was developed by a non-profit organization in 2012. The GM-ITE aimed to assess general clinical knowledge among residents and improve training programs; however, it has not been sufficiently validated is used for high-stake decision-making. This study examined association between another test measure, Professional Linguistic Assessments Board (PLAB) 1 examination.Ninety-seven who completed fiscal year 2019 were recruited took...
To investigate the impact of different ventilatory support options on opioid use among patients with amyotrophic lateral sclerosis (ALS). We retrospectively reviewed 889 consecutive ALS and enrolled 399 eligible patients. All were followed until death or tracheostomy. Clinical characteristics timing initial administration evaluated. Patients categorized into four subgroups: (1) 160 who never used a ventilator, (2) 120 only noninvasive ventilation (NIV), (3) 61 transitioned from NIV to...
To assess the effects of oral care on prolonged viral shedding in coronavirus disease 2019 (COVID-19) patients.We evaluated clinical course eight COVID-19 patients, including their duration shedding, by PCR testing nasopharyngeal swabs. The average time from onset symptoms until virus was no longer detectable 31.6 ± 11.8 days (mean SD; range 17-53). Thus, it took 15.1 14.7 (1-40) recovery for to become undetectable. In two patients who had mental retardation and psychiatric disorders, period...
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Based on the hypothesis that autoimmunity plays a role in pathogenesis of neuralgic amyotrophy (NA), immunotherapy is sometimes administered. Early intervention recommended for good prognosis. We herein report case 55-year-old man who presented with neuralgia, weakness, and muscle atrophy his right shoulder girdle upper arm, which progressed ten months following marine sports accident. The patient was diagnosed NA. His neurological deficits gradually improved after several courses...
We describe a patient with sporadic amyotrophic lateral sclerosis (ALS) who showed progressive deterioration of sensory cortex excitability at the advanced stage, while using invasive ventilation. At time diagnosis, enlarged N20 median nerve somatosensory evoked potential (SEP). Following ventilator use through tracheostomy, gradually fell into totally locked-in state for four years and in amplitude, which finally led to its loss. Magnetic resonance imaging (MRI) frontotemporal mild parietal...
Prednisolone is a frequently prescribed steroid with bitter, unpalatable taste that can result in treatment refusal. Oral suspensions or powder dosage forms are often prescribed, particularly to pediatric patients, as they improve swallowability and ease of dose adjustment. Consequently, the bitterness prednisolone more apparent these forms. Few studies have investigated prednisolone’s bitterness. Thus, this study, 50 adults evaluated using generalized Labeled Magnitude Scale (gLMS),...
Chronic subdural hematoma (CSDH) is a condition that tends to recur frequently. Although middle meningeal artery embolization (MMAE) an effective CSDH treatment, there currently no consensus regarding the optimal timing for embolization.
The 22q11.2 deletion syndrome (22qDS; intractable disease #203 in Japan) is the most common microdeletion syndrome, with an estimated prevalence of 1:2000–1:6000 live births.1 Individuals 22qDS experience various disorders, including congenital heart disease, cleft palate, and intellectual disability. Since has been reported as one greatest risk factors for schizophrenia (odds ratio: 67.7),2 psychiatrists researchers have also focused on 22qDS.3 However, psychosocial burden from...
Parents of children with 22q11.2 deletion syndrome (22q11DS) experience distress not only due to multimorbidity in the patients, but also professionals' lack understanding about 22q11DS and insufficient support systems. This study investigated relationships between medical, welfare, educational challenges parental psychological distress. A cross-sectional survey was conducted on primary caregivers 22q11DS. Participants included 125 parents (114 mothers, 91.2%; average age = 44.3 years) who...
Living in temporary housing is a risk factor for psychological distress after natural disaster. As an essential resource those affected by disasters, investigation of factors which potentially mediate living and needed. This cohort study general population areas the Great East Japan Earthquake 2011. Data were obtained from self-report questionnaires annual health checks between 2014 2016 regarding residential situation (e.g., prefabricated or privately-rented housing), distress, sleep...
Abstract Aim The 22q11.2 deletion syndrome (22q11DS) is associated with a high prevalence of mental health comorbidities. However, not enough attention has been paid to the elevated trait anxiety that begins early in life and may be enduring. We sought identify specific medical, welfare, or educational difficulties 22q11DS. Methods A questionnaire‐based survey was conducted for parents 22q11DS individuals ( N = 125). First, multiple regression analysis confirm hypothesis would parents'...