A5077789012- Viral gastroenteritis research and epidemiology
- Animal Virus Infections Studies
- Animal Disease Management and Epidemiology
- Hepatitis B Virus Studies
- Virus-based gene therapy research
- Microbial infections and disease research
- Viral Infections and Immunology Research
- Rabies epidemiology and control
- Bacillus and Francisella bacterial research
- Monoclonal and Polyclonal Antibodies Research
- Yersinia bacterium, plague, ectoparasites research
- Vector-Borne Animal Diseases
- Animal health and immunology
- Herpesvirus Infections and Treatments
- Brucella: diagnosis, epidemiology, treatment
- Prion Diseases and Protein Misfolding
- Xenotransplantation and immune response
- SARS-CoV-2 and COVID-19 Research
- Veterinary medicine and infectious diseases
- Antimicrobial Resistance in Staphylococcus
- Clostridium difficile and Clostridium perfringens research
- Protein purification and stability
- Medical and Biological Ozone Research
- Zoonotic diseases and public health
- Herbal Medicine Research Studies
Diagnostic and Prevention Research Institute for Human and Animal Diseases
2010-2023
Animal Diseases Research Institute
2021
Asian Association for Dynamic Osteosynthesis
2019
Gamalei Institute of Epidemiology and Microbiology
2019
Ural State Academy of Veterinary Medicine
1994
An outbreak of enteric disease unknown etiology with 60% morbidity and 8% mortality in weaning piglets occurred November 2015 on a farm Buryat Republic, Russia. Metagenomic sequencing revealed the presence rotavirus B feces from diseased while no other pathogens were identified. Clinical was reproduced experimentally infected piglets, yielding 11 RVB gene segments for strain Buryat15, an genotype constellation G12-P[4]-I13-R4-C4-M4-A8-N10-T4-E4-H7. This has also been identified United...
The article provides a comparative assessment of two experimental samples the seven-component vaccine KOMBOVAС-A , manufactured with adjuvants ISA 61 and 50, in terms of: antigenic activity (in laboratory naturally susceptible animals); influence on formation colostral immunity calves when vaccinating pregnant cows, as well effectiveness livestock farming conditions unfavorable for main respiratory intestinal diseases viral etiology. It was found that sample based adjuvant had higher...
Relevance . Rabies, hydrophobia is an acute viral zoonotic neuroinfection with 100% mortality in the case of clinical signs humans or animals. The main biological reservoirs and distributors rabies pathogen (Lyssa virus, Rhabdo viridae) on territory Russian Federation (RF) are wild predators canine family responsible for circulation classic virus (Rabies virus). Also RF countries Eastern Europe, Asia Minor Central Asia, 6 more species viruses genus Lyssavirus, reservation bat populations,...
Introduction. Rotavirus infection is one of the main concerns in infectious pathology humans, mammals and birds. Newborn piglets or rodents are usually being used as a laboratory model for evaluation immunogenicity efficacy all types vaccines against rotavirus A (RVA), use ELISA detection virus-specific antibodies specific isotype an essential step this evaluation.
 Objective. Development indirect solid-phase with VP2/VP6 VLP antigen to detect assess distribution RVA-specific IgG, IgM...
We conducted a cross-sectional study to identify the major respiratory pathogen responsible for an outbreak of disease at swine farm in West Siberia 2019. discovered that peak morbidity and mortality coincided with high level porcine reproductive syndrome virus (PRRSV) 1 2-related viremia. Based on longer PRRSV2 viremia, dominant role over PRRSV1 was assumed. Phylogenetic analysis revealed strain belonged sub-genotype 2—one predominant groups genotype PRRSVs Russia. A partial open reading...
Results of the study structural composition bacterial and fungal microflora isolated from conjunctival swabs calves cows with clinical signs keratoconjunctivitis are given in this paper. Predominance among agents representatives coccal (staphylococci were found 85.06% animals, streptococci 74.71% animals) was revealed. Escherichia coli 74.71%, Proteus spp. 52.87%, Enterobacter 35.63%, Klebsiella 5.75% most frequently microorganisms Enterobacteriaceae. The occurrence frequency bacteria...
Introduction. Rotovirus infection (RVI) caused by the dsRNA-containing virus from genus Rotavirus, Reoviridae family, belonging to group A (RVA), is cause of severe diarrhea in human and other mammalian species. Vaccination most effective way reduce incidence RVI. At present, effectiveness using gnotobiotic piglets as a universal model for reproducing rotavirus assessing quality RVI vaccine preparations has been experimentally proven.Goals objectives. Evaluation immunogenic activity cloned...
Relevance . Rabbit haemorrhagic disease virus type 2 (RHDV-2, GI2,) was first detected in 2010 France and quickly spread across еuropean countries. Unlike strains of the genogroup, RHDV GI2 also affects rabbits under months old, as well various types hares. In addition, causes death vaccinated with vaccines based on 1 hemorrhagic viruses. The rabbit (RHDV-2) during an outbreak disease, characterized by sudden different age groups, summer 2019 a private farm Tula region, Russia. purpose this...
The molecular and biological characteristics of the vaccine against rabies virus strain ERA-CB 20M obtained by Russian rabiologist, doctor medical sciences S.V. Gribencha adapting cloning ERA SAD in a transplantable BHK-21 C13 cell culture are presented. spectrum most sensitive lines was determined level glycoprotein quantitatively determined. Primary nucleotide sequences fragments genome (genes N G) were phylogenetic analysis carried out. Molecular showed that this belongs to group strains...
The publication outlines the results of antigenic activity trials for experimental samples a marker vaccine against classical swine fever (CSF) prepared using different types adjuvants, as well data on duration immunity upon administration this to laboratory and naturally susceptible animals. Live “KS”, widely used specific prophylaxis CSF in Russia, was positive control. obtained indicate that all vaccines stimulated pronounced immune response viral glycoprotein E2, triggering off...
The article presents data on the results of production tests vaccine against streptococcus pigs polyvalent inactivated — “VERRES-STREPTO”. use drug under similar conditions maintenance and feeding allowed to significantly improve such indicators as safety average daily growth in group vaccinated piglets comparison with control.
В статье обобщены данные по развитию поствакцинального иммунного ответа. Приведены характерные особенности основных типов вакцинных препаратов.