A5102984499- Heat shock proteins research
- Effects of Environmental Stressors on Livestock
- Ziziphus Jujuba Studies and Applications
- Pomegranate: compositions and health benefits
- Immune Response and Inflammation
- Viral gastroenteritis research and epidemiology
- Endoplasmic Reticulum Stress and Disease
- Ginseng Biological Effects and Applications
- Ginger and Zingiberaceae research
- Helicobacter pylori-related gastroenterology studies
- Healthcare and Venom Research
- Immune Cell Function and Interaction
- Bioactive natural compounds
- Cardiac electrophysiology and arrhythmias
- Traditional Chinese Medicine Studies
- Animal Behavior and Welfare Studies
- Genomics, phytochemicals, and oxidative stress
- Animal Virus Infections Studies
- Acupuncture Treatment Research Studies
- Vitamin C and Antioxidants Research
- Cynara cardunculus studies
- Milk Quality and Mastitis in Dairy Cows
- Dermatology and Skin Diseases
- Genetics, Aging, and Longevity in Model Organisms
- Autophagy in Disease and Therapy
China Agricultural University
2013-2017
Beijing University of Agriculture
2013
Northwest A&F University
2013
Reactive oxygen species (ROS) and oxidative stress are thought to play a central role in potentiating macrophage activation, causing excessive inflammation, tissue damage, sepsis. Recently, we have shown that punicalagin (PUN) exhibits anti-inflammatory activity LPS-stimulated macrophages. However, the potential antioxidant effects of PUN macrophages remain unclear. Revealing these will help understand mechanism underlying its ability inhibit activation. Hemeoxygenase-1 (HO-1) Therefore,...
As the world warms up, heat stress is becoming a major cause of economic loss in livestock industry. Long-time exposure animals to hyperthermia causes extensive cell apoptosis, which harmful them. AKT and AKT-related serine–threonine kinases are known be involved signaling cascades that regulate survival, but mechanism remains elusive. In present study, we demonstrate phosphoinositide 3-kinase (PI3K) /AKT signal pathway provides protection against apoptosis induced by ascertain key point for...
Jujuboside A is a kind of the saponins isolated from seeds Ziziphus jujuba , which possesses multiple biological effects, such as antianxiety, antioxidant, and anti‐inflammatory effects; however, its mediatory effect on isoproterenol‐stimulated cardiomyocytes has not been investigated yet. In this study, we tried to detect protective potential mechanism JUA ISO‐induced injury. H9C2 cells were treated with ISO induce cell damage. Cells pretreated investigate effects viability, morphological...
We employed comparative proteomics to reveal a heat stress-induced injury mechanism in rat small intestine.
Cardiomyocyte apoptosis is closely associated with the pathogenesis of heart failure. Jujuboside A (JUA) a type saponin isolated from seeds Zizyphus jujuba. In traditional Chinese medicine, it believed that JUA possesses multiple biological effects, including antianxiety, antioxidant and anti‑inflammatory activities. The present study aimed to evaluate effects on norepinephrine (NE)‑induced H9c2 cells investigate its underlying mechanisms. Rat cardiomyocytes were pretreated then exposed NE...
Our previous studies indicated that heat stress can cause significant damage to the intestinal epithelium and induce differential expression of many genes in rat small intestine. The transcription factors AP-1 NF-κB, which act as important mediators by binding specific DNA sequences within gene promoters, regulate associated with immune regulation, response cell fate. To determine whether NF-κB are involved hyperthermia-induced injury intestine IEC-6 cells, we investigated their activity,...
We investigated the mechanisms underlying damage to rat small intestine in heat- and shake-induced stress. Eighteen Sprague-Dawley rats were randomly divided into a control group 3-day stressed treated 2 h daily for 3 days on rotary platform at 35°C 60 r/min. Hematoxylin eosin-stained paraffin sections of jejunum following stress revealed shedding villus tip epithelial cells lamina propria exposure. Apoptosis increased extended basement membrane. Photomicrographs that microvilli shorter...
Purpose: This study aimed to investigate immune-related gene expression in rat small intestine after heat stress. Materials and methods: Twelve Sprague Dawley (SD) rats were randomly divided into control heat-stressed groups. Rats both groups housed at 25 °C with 60% relative humidity. The group was subjected 40 for 2 h/day 3 days. After stress, the mRNA profile of epithelial tissue evaluated by microarray analysis. Results: A total 23 genes related immune responses significantly altered,...
CD8-PE 1.98% 4.56% 1.56% 1.01% 4.61% 1.99% CD4-APC (d) Control group Reserpine SJZ0.2 SJZ0.6 SJZ1
In order to investigate transport stress on porcine peripheral blood lymphocyte subsets and Th cytokines, samples were collected from pigs before after transport. Creatine kinase (CK), alkaline phosphatase (ALP), lactate dehydrogenase (LDH), glucose, cortisol in the serum measured. The number of leukocytes lymphocytes, percentages subsets, as well cell cytokines level their mRNA expression detected, respectively. After transport, CK, glucose interleukin (IL)-4 increased significantly...