A5061786539- Herpesvirus Infections and Treatments
- Family and Disability Support Research
- Pharmacological Effects and Toxicity Studies
- Autism Spectrum Disorder Research
- Pneumonia and Respiratory Infections
- Cytomegalovirus and herpesvirus research
- Liver Disease Diagnosis and Treatment
- Epilepsy research and treatment
- Peptidase Inhibition and Analysis
- Psychosocial Factors Impacting Youth
- Pregnancy and Medication Impact
- Child Development and Digital Technology
- Prostate Cancer Treatment and Research
- Healthcare Education and Workforce Issues
- Hepatitis C virus research
- Diverse Approaches in Healthcare and Education Studies
- Urinary Bladder and Prostate Research
- Liver Disease and Transplantation
- HIV/AIDS Research and Interventions
- Hormonal and reproductive studies
- Cardiac electrophysiology and arrhythmias
- Intensive Care Unit Cognitive Disorders
- Acne and Rosacea Treatments and Effects
- Health and Wellbeing Research
- Thyroid Disorders and Treatments
Takeda (United States)
2024-2025
Analysis Group (United States)
2019-2023
Brigham and Women's Hospital
2018-2019
Harvard University
2018-2019
University of Miami
2018
Emory University
2018
University of Wisconsin–Madison
2018
Kyung Hee University
2017
Yonsei University
2013
To characterize the magnitude and time course of pregnancy-related clearance changes for different antiepileptic drugs (AEDs): levetiracetam, oxcarbazepine, topiramate, phenytoin, valproate. A secondary aim was to determine if a decreased AED serum concentration associated with increased seizure frequency.
To elicit the signs and/or symptoms, and impacts on daily living experienced by patients with alpha-1 antitrypsin deficiency-associated liver disease (AATD-LD). A preliminary "concept list" of was developed from a targeted literature review, patient blog posts, clinician interviews. Subsequently, one-to-one concept elicitation interviews involving English-speaking, US adults AATD-LD protease inhibitor (Pi) ZZ or MZ genotype were conducted trained interviewers following central Institutional...
Patients with chronic obstructive pulmonary disease (COPD) are potentially at increased risk of herpes zoster (HZ). Little is known about the impact an HZ episode on health care resource utilization (HRU) and costs among patients COPD.This retrospective cohort study individuals aged ≥50 years in United States (US) used administrative claims data from Optum's de-identified Clinformatics Data Mart Database for commercially insured Medicare Advantage members (2013-2018). Two cohorts COPD,...
The mechanistic influence of fluid motions, such as a Taylor vortex flow and turbulent eddy flow, on the polymorphic crystallization l-histidine was investigated. Couette–Taylor (CT) mixing tank (MT) crystallizers were used for respectively. Due to its periodic motion, found be more favorable than nucleation stable phase. Thus, fraction phase at induction point (called "initial fraction") in CT crystallizer always much higher that MT all variations conditions, including rotation/agitation...
To evaluate racial and ethnic disparities in postcardiac arrest outcomes patients undergoing targeted temperature management.
Chronic obstructive pulmonary disease (COPD) has been reported as a potential risk factor for developing herpes zoster (HZ). We aimed at comparing incidence rates of HZ between people with versus without COPD in the US. This retrospective cohort study used data from Optum's de-identified Clinformatics Data Mart database 1/1/2013 through 12/31/2018. identified two cohorts ≥40 years prior HZ, vaccination, postherpetic neuralgia (PHN) or ophthalmicus: those (COPD+) and (COPD-) diagnosis....
This study investigated the clinical and economic impact of anti-obesity medications (AOMs; orlistat, liraglutide, phentermine/topiramate extended-release [ER], naltrexone ER/bupropion ER) among United States Veterans with obesity participating in Motivating Overweight/Obese Everywhere! (MOVE!), a government-initiated weight management program. The population was identified from electronic medical records Health Administration (2010–2020). Clinical indices health care resource utilization...
Single-tablet regimens (STRs) can improve antiretroviral therapy (ART) adherence; however, the relationship between long-term adherence and patient healthcare resource utilization (HRU) is unclear. The objective of this study was to assess ART among people living with HIV (PLHIV) using STRs multi-tablet (MTRs) compare HRU over time by adherence. This retrospective analyzed medical pharmacy claims (Optum Clinformatics Data Mart Database). Included PLHIV were aged ≥18 years, had ≥1 claim an...
To evaluate all-cause and liver-associated healthcare resource utilization (HCRU) costs among patients with alpha-1 antitrypsin deficiency (AATD) liver disease (LD) and/or lung (LgD).
Real-world analyses on burden of illness in patients with alpha-1 antitrypsin deficiency (AATD) are limited. We investigated the real-world liver-related clinical events among adult and pediatric AATD USA.
Limited real-world data are available on treatment sequences for patients with metastatic hormone-sensitive prostate cancer treated androgen deprivation therapy plus docetaxel or abiraterone who progress to castrate resistance.Veterans Health Affairs electronic medical records were used analyze 240 men either ("docetaxel cohort," 208 patients, selected be overrepresented, July 2014 August 2018) ("abiraterone 32 December 2016 September received at least 1 after progressing resistance.For and...
Abstract Objective To assess the use and safety of free combination therapy (dutasteride tamsulosin), dutasteride monotherapy, or tamsulosin monotherapy in patients with benign prostatic hyperplasia (BPH). Methods This non-interventional retrospective cohort study used claims data from Korea Health Insurance Review Assessment-National Patient Sample database. Patients BPH ≥ 40 years age receiving 0.5 mg 0.4 daily) mg, daily dose between 2012 2017 were included. The frequency, duration...
The prevalence of chronic hepatitis B virus (HBV) infection is high in many countries; however, robust, real-world epidemiological data are lacking. This study describes the prevalence, characteristics, treatment patterns, and long-term clinical outcomes patients with HBV US, Germany, Taiwan. was a retrospective cohort analysis three healthcare/insurance claims databases. Individuals were identified as if their records contained diagnostic codes from 1 January 2010 to 31 December 2012...
Purpose : This study was conducted to investigate clinical nursing practice hours and framework of three universities programs in the United States order provide basic data improve education Korea. Methods Three BSN were selected by convenience collected for comparison analysis. Data collection based on website designated interviews with nurse practitioners, nurses students at field a university hospital from November 2018 March 2019. Results Clinical between 660 990 US programs. In Korean...
Abstract Background This study compared yearly and longer term antiretroviral (ARV) adherence among HIV patients overall by single-tablet regimens (STRs) vs. multi-tablet (MTRs). Methods A retrospective using Optum Clinformatics US-based claims data was conducted. Patients with an HIV-1 diagnosis during 2011–2017, age ≥ 18 years at index (date of first complete ARV regimen the period), continuous enrollment for 3 months before (baseline) 12 after (observation) were included. MTRs required to...
Abstract Background Previous studies have evaluated the risk of developing herpes zoster (HZ) in patients with chronic obstructive pulmonary disease (COPD), but little is known about impact an acute HZ episode on healthcare resource utilization (HCRU) and costs among COPD US. Methods A retrospective cohort study individuals ≥50 years age was conducted using administrative claims data from Optum Clinformatics for commercially insured Medicare Advantage members (01/01/2013 – 12/31/2018). Two...
The purpose of this study was to examine the effectiveness behavioral parent training (BPT) on problem behaviors in Korean children with developmental disabilities (DD) using a single-group pretest-posttest treatment design. Additionally, collateral effects mothers respect levels depression, stress, self-efficacy, and knowledge behavior modification were analyzed. Participants 60 DD who received 12 weeks BPT groups five six participants. Data regarding changes children’s parenting efficacy,...