A5073186524- Plant Molecular Biology Research
- Plant nutrient uptake and metabolism
- Plant Reproductive Biology
- Plant tissue culture and regeneration
- CRISPR and Genetic Engineering
- Polysaccharides and Plant Cell Walls
- Photosynthetic Processes and Mechanisms
- Chromosomal and Genetic Variations
- Plant-Microbe Interactions and Immunity
- Plant Stress Responses and Tolerance
VIB-UGent Center for Plant Systems Biology
2018-2023
Ghent University
2018-2023
Vlaams Instituut voor Biotechnologie
2019-2023
Detailed functional analyses of many fundamentally important plant genes via conventional loss-of-function approaches are impeded by the severe pleiotropic phenotypes resulting from these losses. In particular, mutations in that required for basic cellular functions and/or reproduction often interfere with generation homozygous mutant plants, precluding further studies. To overcome this limitation, we devised a clustered regularly interspaced short palindromic repeats (CRISPR)-based...
Plant roots explore the soil for water and nutrients, thereby determining plant fitness agricultural yield, as well ground substructure, levels, global carbon sequestration. The colonization of requires investment energy, but how sugar energy signaling are integrated with root branching is unknown. Here, we show through combined genetic chemical modulation pathways that small-molecule signal, trehalose-6-phosphate (T6P) regulates master kinases SNF1-related kinase-1 (SnRK1) Target Rapamycin...
Abstract Throughout the exploration of soil, roots interact with their environment and adapt to different conditions. Directional root growth is guided by asymmetric molecular patterns but how these become established or are dynamically regulated poorly understood. Asymmetric gradients phytohormone auxin during gravitropism, mainly through directional transport mediated polarized transporters. Upon gravistimulation, PIN-FORMED2 (PIN2) differentially distributed accumulates at lower side...
Peptide-receptor signaling is an important system for intercellular communication, regulating many developmental processes. A single process can be controlled by several distinct peptides. However, since peptide-receptor modules are usually studied separately, their mechanistic interactions remain largely unexplored. Two phylogenetically unrelated modules, GLV6/GLV10-RGI and TOLS2/PIP2-RLK7, independently described as inhibitors of lateral root initiation, show striking similarities between...
Abstract Lateral root initiation requires the accumulation of auxin in lateral founder cells, yielding a local maximum. The positioning maxima along primary determines density and spacing roots. GOLVEN6 (GLV6) GLV10 signaling peptides their receptors have been established as regulators via inhibitory effect on Arabidopsis. However, it was unclear how these GLV interfere with or homeostasis. Here, we show that GLV6/10 regulates expression subset response genes, downstream canonical pathway,...
Leucine-rich repeat receptor-like kinases (LRR-RLKs) play fundamental roles in cell-to-cell and plant-environment communication. LRR-RLKs can function as receptors perceiving endogenous or external ligands, coreceptors, which stabilize the complex, enhance transduction of intracellular signal. The LRR-RLK BAK1 is a coreceptor for different developmental immunity pathways. In this article, we identified PXY-CORRELATED 3 (PXC3) BAK1-interacting LRR-RLK, was previously reported to be...
Abstract Detailed functional analyses of many fundamentally-important plant genes via conventional loss-of-function approaches are impeded by severe pleiotropic phenotypes. In particular, mutations in that required for basic cellular functions and/or reproduction often interfere with the generation homozygous mutant plants, precluding further studies. To overcome this limitation, we devised a CRISPR-based tissue-specific knockout system, CRISPR-TSKO, enabling somatic particular cell types,...
Abstract The initiation of lateral roots in Arabidopsis requires the accumulation auxin root founder cells, yielding a local maximum. positioning these maxima along primary determines density and spacing roots. GOLVEN6 (GLV6) GLV10 signaling peptides their receptors have been established as regulators via an inhibitory effect on initiation. However, it remained unclear how GLV interfere with or homeostasis. Here we show that GLV6/10 regulates expression subset response genes during...
Roots, mining for water and nutrients, possess the ability to change their growth direction cope with heterogeneous soil conditions. This directional requires establishment dynamic regulation of asymmetric molecular patterns, poorly understood date. Asymmetric auxin gradients are established during root gravitropism mediated mainly by polarized transporters. Upon gravistimulation differential stabilization PIN2 efflux carrier in apical meristem (RAM) facilitates fluxes primarily through side...
Hosted by New Phytologist Advisor, [Andre Kessler](https://benitezalfonso.wordpress.com/), Centre for Plant Science, University of Leeds.
 
 Featuring
 - Amy Jacobsen, author [Root growth responses to mechanical impedance are regulated a network ROS, ethylene and auxin signalling in Arabidopsis](https://nph.onlinelibrary.wiley.com/doi/10.1111/nph.17180)
 Joris Jourquin, [Two phylogenetically unrelated peptide-receptor modules jointly regulate lateral root initiation via...