Akira Akabayashi

ORCID: 0000-0003-0811-1955
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About
Contact & Profiles
Research Areas
  • Ethics in medical practice
  • Palliative Care and End-of-Life Issues
  • Biomedical Ethics and Regulation
  • Regulation of Appetite and Obesity
  • Organ Donation and Transplantation
  • Patient Dignity and Privacy
  • Ethics and Legal Issues in Pediatric Healthcare
  • Ethics in Clinical Research
  • Neuropeptides and Animal Physiology
  • Hypothalamic control of reproductive hormones
  • Risk Perception and Management
  • Organ Transplantation Techniques and Outcomes
  • Organ and Tissue Transplantation Research
  • Eating Disorders and Behaviors
  • Grief, Bereavement, and Mental Health
  • Neuroethics, Human Enhancement, Biomedical Innovations
  • Reproductive Health and Technologies
  • Patient-Provider Communication in Healthcare
  • Radioactive contamination and transfer
  • Obesity, Physical Activity, Diet
  • Psychosomatic Disorders and Their Treatments
  • Adipose Tissue and Metabolism
  • Nutritional Studies and Diet
  • Psychology of Moral and Emotional Judgment
  • Stress Responses and Cortisol

New York University
2018-2024

The University of Tokyo
2013-2023

Ethics and Public Policy Center
2022

University School
2019

GTx (United States)
2006-2019

Rockefeller University
1993-2009

TCL (China)
2006

Kumamoto University
2006

Kyoto University
2000-2004

John Hunter Hospital
2002

ABSTRACT The Diamond Princess cruise ship has been anchored at the Yokohama port in Japan since February 3, 2020. A total of 691 cases coronavirus disease 2019 (COVID-19) infection had confirmed as 23. government initially assumed that was not spreading aboard and therefore indicated any persons who either tested negative for virus or were asymptomatic should immediately disembark. However, on 5, set a 14-day health observation period because severity infection. Passengers to be free from...

10.1017/dmp.2020.50 article EN cc-by Disaster Medicine and Public Health Preparedness 2020-03-24

Previous studies have suggested that the peptide galanin (GAL) in hypothalamus is related to preference of an animal for dietary fat. The present report investigates this relationship further identify specific GAL-synthesizing cell groups involved and characterize their association circulating glucose or hormones possible contribution body fat deposition. Male albino Sprague Dawley rats were tested different feeding paradigms with diets containing macronutrients, fat, carbohydrate, protein....

10.1523/jneurosci.18-07-02709.1998 article EN cc-by-nc-sa Journal of Neuroscience 1998-04-01

The physiological function of the peptide galanin (Gal) remains to be established. It is known exist in high concentrations within hypothalamus and modulate secretion specific hormones, as well potentiate food consumption. Our study provides evidence for an essential neuronal Gal, a hypothalamic area, stimulating behavioral process fat ingestion body weight gain. Through analyses levels via RIA gene expression situ hybridization, close positive association established between Gal...

10.1073/pnas.91.22.10375 article EN Proceedings of the National Academy of Sciences 1994-10-25

Abstract Although protracted cognitive impairment has been reported to occur after radiotherapy even when such therapy is not directed brain areas, the mechanism remains unclear. This study investigated whether breast cancer patients exposed local showed lower function mediated by higher plasma interleukin ( IL )‐6 levels than those unexposed. We performed Wechsler Memory Scale‐Revised WMS ‐R) and measured ‐6 for 105 surgical within 1 year initial therapy. The group differences in each of...

10.1002/cam4.174 article EN Cancer Medicine 2014-04-23

<h2>Abstract</h2> In order to explore possible differences in the scope of end-of-life decisions and attitudes toward advance directives (AD) palliative care, we conducted a survey 159 patients care institutions 93 health-care professionals experienced United States, Germany, Japan. Giving an AD this clinical setting was considered important by professionals. The prevalence formal written 79% 18% 9% Japan, there high entrusting all family (known as omakase). More than 80% had negative...

10.1016/s0885-3924(98)00067-0 article EN cc-by-nc-nd Journal of Pain and Symptom Management 1998-09-01

Background: The purpose of this study was to determine the discriminate gender-specific cutoff values waist circumference (WC) for detecting clustering cardiovascular risk factors (CCRF), which reflects intra-abdominal visceral fat area (VFA) using a large Japanese population. Methods and Results: population consisted 6,736 men women who underwent periodic health check-up had computed tomography scan VFA measurement at PL Tokyo Health Care Center in Tokyo, Japan. CCRF defined according...

10.1253/circj.cj-09-0183 article EN Circulation Journal 2009-01-01

Previous studies on the association between physical activity (PA) and neighborhood environments (NE) focused either objectively measuring NE or residents' perception of NE. Here, we investigate which actual perceived is associated with PA in Japan.Two regions an assessed high low residential density, land use mix-diversity, street connectivity, respectively, were identified one city. The subjects selected using a stratified random sampling method by sex age each region. was measured...

10.1007/s12199-009-0081-1 article EN cc-by Environmental Health and Preventive Medicine 2009-03-18

Most medical schools in Japan have incorporated mandatory courses on ethics. To this date, however, there is no established means of evaluating ethics education Japan. This study looks 1) develop a brief, objective method evaluation for moral sensitivity and reasoning; 2) conduct test battery the PIT DIT students who are either currently school or recently graduated (residents); 3) investigate changes reasoning between years among residents.Questionnaire survey: Two questionnaires were...

10.1186/1472-6939-5-1 article EN cc-by BMC Medical Ethics 2004-01-29

Recalled evaluation of headache intensity is often affected by several factors. Recently, computerized ecological momentary assessment (EMA) has been developed to avoid such problems as recall bias. Here, we compared recalled with using EMA in tension-type (TTH). Forty patients TTH wore watch-type computers for 1 week record and also rated their intensities recall. We calculated intraclass correlation coefficients between indices from recordings the whole study population two subgroups...

10.1111/j.1468-2982.2006.01221.x article EN Cephalalgia 2006-10-24

Aims: Sociocultural factors are thought to be important in the pathogenesis of eating disorders. However, there have been few studies comparing behavior among various cultural populations. The aim present study is compare attitudes towards bodyweight and shape, desire for thinness Japanese male female subjects with those people from other countries different ethnic origin. Methods: were 411 Japanese, 130 Indian, 135 Omani, 113 Euro‐American 196 Filipino adolescents. Eating Attitude Test‐26...

10.1111/j.1440-1819.2007.01772.x article EN Psychiatry and Clinical Neurosciences 2008-02-01

In Japan, discussion concerning advance directives (ADs) has been on the rise during past decade. ADs are one method proposed to facilitate process of communication among patients, families and health care providers regarding plan a patient who is no longer capable communicating. this paper, we report results first in-depth survey general population preferences use in Japan.A self-administered questionnaire was sent via mail stratified random sampling 560 residents listed residential...

10.1186/1472-6939-4-5 article EN cc-by BMC Medical Ethics 2003-10-31

The neuropeptides, galanin (GAL) and neuropeptide Y (NPY), based on studies in male rodents, are believed to have a role controlling energy balance, both nutrient ingestion metabolism. Whereas these peptides also involved reproduction, little is known about their specific function balance females. In rats consuming lab chow or macronutrient diets, measurements across the estrous cycle were taken of hypothalamic GAL NPY, using RIA immunohistochemistry; circulating hormones, estradiol,...

10.1210/endo.139.4.5867 article EN Endocrinology 1998-04-01

Informed consent, decision-making styles and the role of patient-physician relationships are imperative aspects clinical medicine worldwide. We present case a 74-year-old woman afflicted with advanced liver cancer whose attending physician, per request family, did not inform her true diagnosis. In our analysis, we explore differences in informed-consent between patients who hold an "independent" "interdependent" construal self then highlight possible implications maintained by this position...

10.1080/15265160500394549 article EN The American Journal of Bioethics 2006-01-01

This study examined the decision-making processes of donors in adult-to-adult living donor liver transplantation. Twenty-two were interviewed using a semi-structured format. Interview contents transcribed verbatim and analyzed qualitatively grounded theory. A model was developed consisting 5 stages: (1) recognition, (2) digestion, (3) decision-making, (4) reinforcement, (5) resolution. The second third stages described donors' experiences "reaching decision"; fourth fifth those "facing...

10.1002/lt.20689 article EN Liver Transplantation 2006-01-01

Many physical diseases have been reported to be associated with psychosocial factors. In these diseases, assessment relies mainly on subjective symptoms in natural settings. Therefore, it is important assess and/or relationships between factors and Symptoms are usually assessed by self-report when patients visit their doctors. However, recall has an intrinsic problem; "recall bias". Recently, ecological momentary (EMA) proposed as a reliable method record events well physiological behavioral...

10.1186/1751-0759-2-13 article EN cc-by BioPsychoSocial Medicine 2008-07-11

Anorexia nervosa (AN) is considered to have a significant risk for sudden death because of cardiac complications, and abnormalities the autonomic nervous system might be cause dysfunction. The aim this study was investigate function in AN patients by analyzing heart rate variability (HRV), blood pressure (BPV), baroreflex sensitivity (BRS).The subjects were 32 without other psychiatric comorbidities 37 healthy controls. Beat-to-beat R-R interval systolic recorded supine position analyzed...

10.1097/psy.0b013e31817bb090 article EN Psychosomatic Medicine 2008-07-01
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