A5008925445- Graphene and Nanomaterials Applications
- Digital Holography and Microscopy
- Bone Tissue Engineering Materials
- Electrospun Nanofibers in Biomedical Applications
- Nanoparticle-Based Drug Delivery
- Near-Field Optical Microscopy
- Dental materials and restorations
- Analytical Chemistry and Sensors
- Fiber-reinforced polymer composites
- Cell Image Analysis Techniques
- Dental Implant Techniques and Outcomes
- Laser Material Processing Techniques
- Advanced Sensor and Energy Harvesting Materials
- Cellular Mechanics and Interactions
- 3D Printing in Biomedical Research
- Structural Behavior of Reinforced Concrete
- Diverse Scientific Research Studies
- Spectroscopy and Chemometric Analyses
- biodegradable polymer synthesis and properties
- Microfluidic and Bio-sensing Technologies
- Nanoparticles: synthesis and applications
- Advanced Electron Microscopy Techniques and Applications
- Photoacoustic and Ultrasonic Imaging
- Erythrocyte Function and Pathophysiology
- Mesoporous Materials and Catalysis
Horia Hulubei National Institute for R and D in Physics and Nuclear Engineering
2017-2024
Universitatea Națională de Știință și Tehnologie Politehnica București
2013-2024
The novel controlled and localized delivery of drug molecules to target tissues using an external electric stimulus makes electro-responsive systems both feasible desirable, as well entailing a reduction in the side effects. Novel micro-scaffold matrices were designed based on poly(lactic acid) (PLA) graphene oxide (GO) via electrospinning. Quercetin (Q), natural flavonoid, was loaded into fiber order investigate potential model for wound dressing applications. physico-chemical properties,...
In this paper, novel drug delivery systems (DDS) were designed based on graphene oxide (GO) as nanocarrier, loaded with two natural substances (quercetin (Qu) and juglone (Ju)) at different concentrations. The chemical structure morphology of the synthesized GO-based materials characterized by Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), Raman spectroscopy. antibacterial activity was evaluated against standard strains, Staphylococcus aureus ATCC 6538,...
The effect of micropatterned polymeric scaffolds on the features cultured cells at different time intervals after seeding was investigated by digital holographic microscopy. Both parallel and perpendicular walls, with heights, were fabricated using two-photon lithography photopolymers. walls subsequently coated polypyrrole-based thin films matrix assisted pulsed laser evaporation technique. Osteoblast-like cells, MG-63 line, these 3D scaffolds. To analyze with/without an inverted microscope,...
This study explores the potential utilization of walstromite (BaCa2Si3O9) as a foundational material for creating new bioceramics in form scaffolds through 3D printing technology. To achieve this objective, investigates chemical–mineralogical, morphological, and structural characteristics, well biological properties, walstromite-based bioceramics. The precursor mixture synthesis is prepared sol–gel method, utilizing pure reagents. resulting dried gelatinous precipitate analyzed complex...
Replicating the intricate architecture of extracellular matrix (ECM) is an actual challenge in field bone tissue engineering. In present research study, calcium alginate/cellulose nanofibrils-based 3D printed scaffolds, double-reinforced with chitosan/polyethylene oxide electrospun nanofibers (NFs) and graphene (GO) were prepared using printing technique. The porous was provided by alginate, while anisotropy degree mechanical properties ensured addition fillers different sizes shapes (CNFs,...
We fabricated polymeric microscaffolds with deep walls for biomedical applications. To characterize its microrelief, we used digital holographic microscopy. The phase information recorded in holograms provides the depth and refractive index of walls.
This study is presenting the theoretical approach and practical results of a precise activity involved in hologram reconstruction order to find optimally focused image MG63 osteoblast-like cells cultivated on polymeric flat substrates. The morphology dynamic cell investigated by digital holographic microscopy (DHM) technique. digitally performed using an algorithm based scalar theory diffraction Fresnel approximation. quality 3D images crucially depending focusing capability chain fit...
The study of cells-substrate interaction became a stringent subject in the past decades, since an increasing variety new materials and methods have been involved tissue engineering or implants techniques. investigation this using optical is challenge, especially these substrates are not optically polished. Due to their roughness micrometric submicrometric range, polymeric offers good conditions for cells adhesion, but characterization properties can be hindered. In study, we use Polypyrrole...