A5049538117- Polyamine Metabolism and Applications
- Nerve injury and regeneration
- Neuroscience and Neuropharmacology Research
- Amino Acid Enzymes and Metabolism
- Cannabis and Cannabinoid Research
- Neuroscience of respiration and sleep
- Stress Responses and Cortisol
- Neurotransmitter Receptor Influence on Behavior
- Receptor Mechanisms and Signaling
- Memory and Neural Mechanisms
- Neurogenesis and neuroplasticity mechanisms
- Biochemical effects in animals
- Neuropeptides and Animal Physiology
- Cholinesterase and Neurodegenerative Diseases
- Adipose Tissue and Metabolism
- Nicotinic Acetylcholine Receptors Study
- Neuroendocrine regulation and behavior
- Pain Mechanisms and Treatments
- Blood properties and coagulation
- Botulinum Toxin and Related Neurological Disorders
- Neurological Disorders and Treatments
- Olfactory and Sensory Function Studies
- Neuroinflammation and Neurodegeneration Mechanisms
- Anesthesia and Neurotoxicity Research
- Plant-based Medicinal Research
Alameda Hospital
2014
Assaf Harofeh Medical Center
1998-2013
Tel Aviv University
1986-2013
Ben-Gurion University of the Negev
2004-2005
UConn Health
1998
Society for Neuroscience
1998
Tel Aviv Sourasky Medical Center
1986-1996
Technion – Israel Institute of Technology
1994-1995
Johns Hopkins Medicine
1995
Johns Hopkins University
1995
Objective. Agmatine, decarboxylated arginine, was shown in preclinical studies to exert efficacious neuroprotection by interacting with multiple molecular targets. This study designed ascertain safety and efficacy of dietary agmatine sulfate herniated lumbar disc-associated radiculopathy. Study Design. First, an open-label dose escalation performed assess the side-effects sulfate. In follow-up study, participants diagnosed radiculopathy were randomly assigned receive either placebo or a...
Abstract— Changes in the activities of several specific enzymes were measured cerebellum during development. Early transient increases found both ornithine decarboxylase and S ‐adenosylmethionine decarboxylase, involved initial steps polyamine synthesis. Different patterns changes neurotransmitter synthesizing enzymes. Tyrosine hydroxylase activity achieved adult levels very early, by 3 days after birth, remained at this level. Glutamic acid activity, while low early stages, increased...
Abstract: The activity of transglutaminase (TG) was examined in the rat superior cervical ganglion (SCG) during development and after postganglionic nerve crush. During postnatal enzyme is increased by sevenfold parallel to protein content reaches adult levels day 35 birth. endogenous (enzyme assayed absence exogenous substrate) transiently elevated with a peak at 21 postnatal. In specific evenly distributed all subcellular compartments, but most it contained cytosol. Within first hour...
Abstract: The activity of transglutaminase was characterized in the rat brain. In adults, comparable levels are present all brain regions examined. is subcellular fractions, as studied by differential centrifugation, but soluble fraction contains highest specific activity. endogenous (enzyme assayed absence exogenous substrate casein) very low except synaptosomal where its about 40–60% presence casein. Furthermore, enzyme on external surface synaptosomes. fraction, maximal can be detected...