A5032346357- Growth Hormone and Insulin-like Growth Factors
- Diabetes Management and Research
- Breastfeeding Practices and Influences
- Cystic Fibrosis Research Advances
- Diabetes Treatment and Management
- Pancreatic function and diabetes
- Neuroendocrine regulation and behavior
- Acute Lymphoblastic Leukemia research
- Pituitary Gland Disorders and Treatments
- Radiomics and Machine Learning in Medical Imaging
- Hemoglobinopathies and Related Disorders
- Neuroscience of respiration and sleep
- Ultrasound and Hyperthermia Applications
- Blood Coagulation and Thrombosis Mechanisms
- Genetic Syndromes and Imprinting
- Respiratory Support and Mechanisms
- Congenital Ear and Nasal Anomalies
- Biological Stains and Phytochemicals
- Cancer Risks and Factors
- Ferroptosis and cancer prognosis
- Ovarian cancer diagnosis and treatment
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Psychology and Mental Health
- Genetics and Neurodevelopmental Disorders
- Digestive system and related health
The University of Texas Medical Branch at Galveston
2021
University of Perugia
1990-2020
Sapienza University of Rome
2010-2020
Galveston College
2020
University of Liverpool
2015
Liverpool Heart and Chest Hospital
2015
Women's and Children's Hospital
2015
Università di Camerino
2013
Azienda Ospedaliera Sant'Andrea
2009
To prove equivalence of individual, clinically titrated basal insulin doses glargine 300 units ⋅ mL-1 (Gla-300) and degludec 100 (Deg-100) under steady state conditions in a single-blind, randomized, crossover study, on the glucose pharmacodynamics (PD) people with type 1 diabetes (T1D).Subjects T1D (N = 22, 11 men, age 44.3 ± 12.4 years, disease duration 25.5 11.7 A1C 7.07 0.63% [53.7 6.9 mmol mL-1], BMI 22.5 2.7 kg · m-2), naïve to Gla-300 Deg-100, underwent 24-h euglycemic clamps...
Primary empty sella (PES) is a particular anatomical condition characterized by the herniation of liquor within turcica. The pathogenesis this alteration, frequently observed in general population, not yet completely understood. Recently reports demonstrated, these patients, that hormonal pituitary dysfunctions, specially growth hormone (GH)/insulin- like factor (IGF-I) axis ones, could be relevant. aim paper to evaluate GH/IGF-I group adult patients affected PES and verify its clinical...
Thromboembolic complications have been reported after diagnostic or interventional radiological procedures. However, contrast media inhibit platelet function and blood coagulation in vitro. To investigate these characteristics vivo, we determined the effect of nonionic ionic low osmolar on thrombus growth thrombolysis rabbits a randomized study design. Rabbits received either medium (ioxaglate), (iohexol) saline. Thrombus was by accretion 125I-labeled fibrinogen to autologous,...
In Italy, even though olanzapine has been discouraged for treatment of behaviour disorders in older patients affected by dementia, some physicians chose to prescribe them. response this situation, the Italian Drug Agency (Agenzia Italiana del Farmaco, AIFA) promulgated a cautionary note.This study examined epidemiological indices prescriptions between 2004 and 2007 Marche Region central Italy its provinces, assess physician compliance with AIFA note, determine whether there were differences...
The aim of this study was to investigate the relationship between dynamic hyperinflation and daily physical activity (DPA) in adults with cystic fibrosis (CF). Thirty-four clinically stable CF were studied. All patients undertook incremental cardiopulmonary exercise testing (CPET). CPET-related measurements included: oxygen uptake (V'O2), carbon dioxide production (V'CO2), ventilatory profile, work rate (W), inspiratory capacity (IC), end-expiratory lung volume (EELV). PA assessed using...
Aim: to compare head-to-head pharmacokinetics (PK), pharmacodynamics (PD), glucose fluxes and lipid metabolism of clinical doses insulin glargine U300 (Gla-300) degludec U100 (IDeg) in real life T1DM. Methods: 22 subjects [(11M, age 44±12, T1DM for 26±12 years, BMI 22.5±3.2 kg/m2, A1C 7.1±0.6% (53.4±7.1 mmol/mol)] on Gla-100, naïve Gla-300 IDeg, were studied (24h euglycemic clamp) with individual IDeg (dosing at 20.0h) after 3 months optimal titration basal-bolus (random crossover). Results...
Abstract Obese older adults often have sarcopenia with increased functional impairments. Unfortunately, conventional weight loss treatments can lead to further muscle mass loss. Increasing evidence from animal studies suggests that the pituitary hormone oxytocin has trophic effects on skeletal cells and induce We piloted a clinical trial testing whether intranasal would decrease adiposity without lowering in sarcopenic obesity. Twenty-one (≥60years), obese (30-43kg/m2), sedentary (<2...
Obesity leads to sarcopenia and poor physical function with aging. Evidence in animals middle-age humans suggests that the pituitary hormone oxytocin reduces appetite, promotes weight loss, improves glucose tolerance while preserving lean muscle mass. We studied oxytocin’s effect on body mass index (BMI), tolerance, mass, an older adult population sarcopenic obesity. Twenty-one (≥60 yrs), obese (30-43 kg/m2), sedentary (<2 exercise/week) adults slow gait (<1 m/sec) were...
<b>OBJECTIVE</b> <p><b> </b></p> <p>To prove equivalence of individual, clinically-titrated basal insulin doses Gla-300 and Deg-100 under steady-state conditions in a single-blind, randomized, crossover study, on the glucodynamics (PD) people with type 1 diabetes (T1DM).</p> <p><b>RESEARCH DESIGN AND METHODS</b></p> <p>T1DM subjects [N=22, 11 males M, age 44.3±12.4 years, disease duration 25.5±11.7 A1C 7.07±0.63%...
<b>OBJECTIVE</b> <p><b> </b></p> <p>To prove equivalence of individual, clinically-titrated basal insulin doses Gla-300 and Deg-100 under steady-state conditions in a single-blind, randomized, crossover study, on the glucodynamics (PD) people with type 1 diabetes (T1DM).</p> <p><b>RESEARCH DESIGN AND METHODS</b></p> <p>T1DM subjects [N=22, 11 males M, age 44.3±12.4 years, disease duration 25.5±11.7 A1C 7.07±0.63%...