A5038500797- Respiratory Support and Mechanisms
- COVID-19 Clinical Research Studies
- Systemic Sclerosis and Related Diseases
- Long-Term Effects of COVID-19
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Sepsis Diagnosis and Treatment
- Pulmonary Hypertension Research and Treatments
- Medical Imaging and Pathology Studies
- Pleural and Pulmonary Diseases
- Body Contouring and Surgery
- Respiratory and Cough-Related Research
- Mast cells and histamine
- Connective Tissue Growth Factor Research
- Venous Thromboembolism Diagnosis and Management
- SARS-CoV-2 and COVID-19 Research
- Gastroesophageal reflux and treatments
- Dysphagia Assessment and Management
- Neonatal Respiratory Health Research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Neuroblastoma Research and Treatments
- Liver Disease and Transplantation
- Diagnosis and Treatment of Venous Diseases
- Cardiac Arrest and Resuscitation
- Sarcoidosis and Beryllium Toxicity Research
University of Trieste
2022-2024
Ospedale San Paolo
2022
University of Milan
2022
Ospedale di Cattinara
2022
Glucocorticoids (GCs) have been shown to reduce mortality and the need for invasive mechanical ventilation (IMV) in SARS-CoV-2-induced acute respiratory distress syndrome (ARDS). It has suggested that serum cytokines levels are markers of disease severity ARDS, although there is only limited evidence a relationship between longitudinal cytokine profile clinical outcomes patients with ARDS treated GC.We conducted single-center observational study investigate serial plasma 17 supported...
Background Dysregulated systemic inflammation is the primary driver of mortality in severe coronavirus disease 2019 (COVID-19) pneumonia. Current guidelines favour a 7–10-day course any glucocorticoid equivalent to dexamethasone 6 mg daily. A comparative randomised controlled trial (RCT) with higher dose and longer duration intervention was lacking. Methods We conducted multicentre, open-label RCT investigate methylprednisolone 80 as continuous daily infusion for 8 days followed by slow...
Idiopathic pulmonary fibrosis (IPF) is a rare and severe disease with median survival of ~3 years. Nintedanib (NTD) has been shown to be useful in controlling interstitial lung (ILD) IPF. Here we describe the experience NTD use IPF real-life setting. Objective. Our objective was examine safety profile efficacy nintedanib even subjects treated anticoagulants. Clinical data patients at our center were retrospectively evaluated baseline 6 12 months after introduction NTD. The following...
Severe pneumonia caused by coronavirus disease 2019 (COVID-19) is characterized inflammatory lung injury, progressive parenchymal stiffening and consolidation, alveolar airway collapse, altered vascular permeability, diffuse damage, surfactant deficiency. COVID-19 causes both acute respiratory distress syndrome (COVID-19 ARDS). ARDS severe refractory hypoxemia high mortality. Despite extensive research, the treatment of far from satisfactory. Some treatments are recommended for exhibiting...
Background and Objectives: Chronic thromboembolic pulmonary hypertension (CTEPH) has a high mortality. The treatment of CTEPH could be balloon angioplasty (BPA), medical (MT) or endarterectomy (PEA). This study aims to assess the clinical characteristics patients, surgically medically treated, in pulmonology referral center. Materials Methods: A total 124 patients with PH suspected (53 male subjects 71 female subjects; mean age at diagnosis 67 ± 6) were asked give informed consent then...
Background: Oscillometry allows for the non-invasive measurements of lung mechanics. In COVID-19 ARDS patients treated with Non-Invasive Oxygen Support (NI-OS), we aimed to (1) observe mechanics at patients’ admission and their subsequent changes, (2) compare clinical imaging data, (3) evaluate whether helps predict outcomes. Methods: We retrospectively analyzed data from 37 consecutive moderate–severe ARDS. was performed on 1st, 4th, 7th day hospitalization. Resistance (R5), reactance (X5),...
The diagnostic process of pulmonary fibrosis (PF) is often challenging, requires a collaborative effort several experts, and bioptic material, which can be difficult to obtain, both in terms quality technique. main procedures available obtain such samples are transbronchial lung cryobiopsy (TBLC) surgical biopsy (SLB).The purpose this paper review the evidence for role TBLC diagnostic-therapeutic PF.A comprehensive was performed identify articles date that addressed PF using PubMed®...
<b>Introduction.</b> Systemic sclerosis (SSc) is a rare connective tissue disease. Interstitial lung disease and pulmonary arterial hypertension (PAH) are the main features of SSc. Transthoracic echocardiography common technique for screening PAH, but right heart catheterization (RHC) required to confirm diagnosis (1). Several studies have shown that nail fold videocapillaroscopy (NVC), validated tool study microvascular damage, can predict involvement <b>Objective.</b> To evaluate possible...