A5101552886- Neonatal Respiratory Health Research
- Neuroscience of respiration and sleep
- Infant Development and Preterm Care
- Cardiac Arrest and Resuscitation
- Respiratory Support and Mechanisms
- Airway Management and Intubation Techniques
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cardiac, Anesthesia and Surgical Outcomes
- Congenital Diaphragmatic Hernia Studies
- Neonatal and fetal brain pathology
- Musculoskeletal pain and rehabilitation
- Non-Invasive Vital Sign Monitoring
- Infant Health and Development
- Cardiac and Coronary Surgery Techniques
- Central Venous Catheters and Hemodialysis
- Anesthesia and Pain Management
- Pressure Ulcer Prevention and Management
- PI3K/AKT/mTOR signaling in cancer
- Tumors and Oncological Cases
- Hemophilia Treatment and Research
- Hip and Femur Fractures
- Tracheal and airway disorders
- Clinical Nutrition and Gastroenterology
- Neonatal skin health care
- Pediatric health and respiratory diseases
National Maternity Hospital
2016-2025
University College Dublin
2012-2024
Hospital for Sick Children
2022
Indiana University School of Medicine
2020-2021
St Helens and Knowsley Teaching Hospitals NHS Trust
2020
Prince Charles Hospital
2019
Our Lady's Hospital
2018
Auckland City Hospital
2017
National Children’s Research Centre
2011-2016
Lexington City Schools
2016
BackgroundRepeated attempts at endotracheal intubation are associated with increased adverse events in neonates. When clinicians view the airway directly a laryngoscope, fewer than half of first successful. The use video which has camera tip blade that displays on screen, been greater percentage successful intubations attempt direct laryngoscopy adults and children. effect among neonates is uncertain.MethodsIn this single-center trial, we randomly assigned any gestational age who were...
Summary We undertook a randomised, controlled trial to compare the analgesic efficacy and opioid sparing effect of nerve stimulator‐guided femoral block with fascia iliaca compartment in patients awaiting surgery for fractured neck femur. Ten‐centimetre visual analogue pain scores were measured before 2 h after consumption was recorded 12‐h period block. One hundred ten randomly assigned. Femoral provided superior pre‐operative analgesia femur compared The difference mean reduction score 0.9...
To compare the admission temperature of infants treated with polyethylene bags alone to exothermic mattresses in addition delivery room.We prospectively studied born at <31 weeks' gestation who were placed birth. Some also on mattresses. Admission axillary temperatures measured all neonatal intensive care. We compared those and bags.We 43 infants: 15 while 28 a bag mattress. Mean was similar between groups. Hypothermia hyperthermia occurred more frequently mattress, had 36.5-37.5°C.The use...
Resuscitation guidelines recommend that respiratory support should be given to newborns via a face mask (FM) in the delivery room (DR). Respiratory preterm single nasal prong (SNP; ie, short tube, nasopharyngeal tube) may more effective. We wished determine whether giving with SNP rather than FM reduces rate of intubation DR.Infants <31 weeks' gestation were randomized just before (endotracheal tube shortened 5 cm) or FM. Randomization was stratified by (<28 weeks, 28-30(+6)). Infants apnea,...
Hypothermia on admission to the neonatal intensive care unit (NICU) is associated with an increased risk of death in preterm infants. There are currently no evidence-based recommendations for thermal before cord clamping (CC). We wished determine whether placing very infants a polyethylene bag (PB) CC, compared after results more temperature normal range NICU admission.
Clinical assessment of an infant’s heart rate (HR) in the delivery room (DR) has been reported to be inaccurate. We compared auscultation HR using a stethoscope with electrocardiography (ECG) and pulse oximetry (PO) for determining 92 low-risk newborn infants DR. Caregivers auscultated while masked on monitor. Auscultation underestimated ECG (mean difference (95% CI) by −9 (−15 –2) beats per minute (bpm)) PO −5 (−12 2) bpm). The median (IQR) time was 14 (10–18) s. As determined quickly...
Aim To determine whether IntelliVue (ECG plus Masimo pulse oximeter (PO)) measures heart rate (HR) in low-risk newborns more quickly than Nellcor PO (PO alone). Methods Unmasked parallel group randomised (1:1) study. Results We studied 100 infants, 47 to IntelliVue, 53 Nellcor. Time first HR was shorter with ECG (median (IQR) 24 (19, 39) vs 48 (36, 69) s, p<0.001). There no difference time display both and SpO 2 (52 (47, 76) p=0.507). displayed initial bradycardia often the (55% 6%)....
Objective To compare rectal and axillary temperatures in preterm newborns on admission to the neonatal intensive care unit (NICU). Design Secondary analysis of data collected a randomised controlled trial (RCT). Setting Maternity hospital, level 3 NICU. Patients Seventy-two <31 weeks who were enrolled BAMBINO RCT (A exothermic mattresses prevent heat loss infants at birth, ISRCTN31707342 ). Interventions Newborns placed polyethylene bags placement mattresses, or not delivery room. All had...
To determine the frequency and pattern of cerebellar haemorrhage (CBH) on routine cranial ultrasound (cUS) imaging in infants ≤32 weeks gestation, to investigate how extremely preterm with CBH differ from those severe intraventricular (IVH).672 gestation were prospectively examined for serial cUS imaging. In a separate case--control analysis, clinical features, findings outcome compared isolated IVH (grade III-IV).Nine cases identified among 53 IVH. The incidence was 1.3%. Five had bilateral...
Introduction Chronic obstructive pulmonary disease (COPD) is the fourth leading cause of death globally. In outpatient care, self-management COPD essential, but patient adherence to this remains suboptimal. The objective study examine whether an innovative mobile health (mHealth)-enabled care programme (MH-COPD) will improve and relevant outcomes. Methods analysis A prospective open randomised controlled trial has been designed. trial, patients with be recruited from Prince Charles Hospital,...
(Abstracted from Anesthesiology, 125(3):465–473, 2016) More than 1.25 million undergo cardiopulmonary bypass (CPB) annually. The purpose of this multicenter, randomized controlled trial was to assess whether avoiding arterial hyperoxemia would reduce the severity multiorgan dysfunction (MOD) in those undergoing CPB.
Neonatal resuscitation algorithms recommend assessing breathing and heart rate (HR) of newborns giving respiratory support when one or both are unsatisfactory. Recommendations also state that preterm infants may be supported with continuous positive airway pressure rather than routinely intubated for ventilation (PPV). We wished to describe the prevalence time initiation extremely low birthweight (ELBW) at our hospital. reviewed videos 55 infants. Although most were breathing, practically...
Guidelines recommend delayed cord clamping (DCC) of at least 30 s for vigorous preterm infants who do not require resuscitation. It is known whether DCC affects the rate crying and breathing after birth. We reviewed videos 80 in delivery room. Most cried breathed both immediate before respiratory support was given. Infants arrived resuscitaire similar physiological condition, regardless time birth which they arrived.
<h3>Background</h3> Basic life support guidelines recommend placing spontaneously breathing children and adults on their side. Though the majority of preterm newborns breathe spontaneously, they are routinely placed back after birth. We hypothesised that would more effectively when <h3>Objective</h3> To determine whether left side at birth, compared with those back, have higher preductal oxygen saturation (SpO<sub>2</sub>) 5 min life. <h3>Design/methods</h3> randomised infants <32 weeks...
Aim To determine whether the IntelliVue monitor (ECG plus Masimo pulse oximeter (PO)) displays heart rate (HR) at birth more quickly than Nellcor PO (PO alone) among infants of 29–35 weeks’ gestational age. Methods Unmasked parallel group randomised (1:1) study. Results We planned to enrol 100 infants; however, study was terminated due COVID-19 pandemic when 39 had been enrolled (17 IntelliVue, 22 Nellcor). found no differences between groups in time first HR display (median (IQR) ECG 49...