A5046330272- Diabetes Treatment and Management
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Lipoproteins and Cardiovascular Health
- Cardiovascular Function and Risk Factors
- Metabolism, Diabetes, and Cancer
- Protein Structure and Dynamics
- Cardiac Imaging and Diagnostics
- Spectroscopy and Quantum Chemical Studies
- Quantum chaos and dynamical systems
- Aortic Thrombus and Embolism
- Advanced Thermodynamics and Statistical Mechanics
- Peroxisome Proliferator-Activated Receptors
- Adipokines, Inflammation, and Metabolic Diseases
- Nonlinear Dynamics and Pattern Formation
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Aortic aneurysm repair treatments
- Molecular spectroscopy and chirality
- Theoretical and Computational Physics
- Enzyme Structure and Function
- Acute Myocardial Infarction Research
- Health Systems, Economic Evaluations, Quality of Life
- Atherosclerosis and Cardiovascular Diseases
- Cold Fusion and Nuclear Reactions
- Cancer, Lipids, and Metabolism
- Antiplatelet Therapy and Cardiovascular Diseases
Sapienza University of Rome
2002-2024
Tel Aviv University
2011-2021
University of Toronto
2018-2020
Sheba Medical Center
2008-2019
Israel Ministry of Health
2016
Israeli Association for Cardiovascular Trials
2016
University of Rochester Medical Center
2016
Wolfson Medical Center
2006
University of Rome Tor Vergata
2002
Tel Aviv Sourasky Medical Center
2001
We have developed a technique to produce stationary nonequilibrium states in molecular-dynamics system; this method is based on the introduction of stochastic boundary conditions simulate contact with thermal wall. The relaxation times involved such are short enough (\ensuremath{\sim}${10}^{\ensuremath{-}11}$ sec) make suitable for computer experiments. allows simulation bulk properties system coupled heat reservoir and study local thermodynamical equilibrium. Furthermore, it gives physical...
The independent association between elevated triglycerides and all-cause mortality among patients with established coronary heart disease is controversial. aim of this study was to investigate in a large cohort proven disease.The comprised 15 355 who were screened for the Bezafibrate Infarction Prevention (BIP) trial. Twenty-two-year data obtained from national registry. Patients divided into 5 groups according strata fasting serum triglycerides: (1) low-normal (<100 mg/dL); (2) high-normal...
Incretin hormones are peptides released in the intestine response to presence of nutrients its lumen. The main incretins glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). GLP-1 stimulates insulin secretion, inhibits glucagon secretion at pancreatic α cells has also extrapancreatic influences as slowing gastric emptying which increases feeling satiety. GIP is incretin hormone healthy people, causative most effects, but after type 2 diabetes mellitus...
Recent studies have shown that type 2 diabetes is preventable by both lifestyle interventions and medications influence primary glucose metabolism. Whether pharmacological lipid metabolism can also delay development of unknown. The goal this study was to evaluate the effect peroxisome proliferator-activated receptor ligand bezafibrate on progression impaired fasting phase in patients with coronary artery disease over a 6.2-year follow-up period.The sample comprised 303 nondiabetic 42 74...
A sulfonylurea--usually glyburide--plus metformin constitute the most widely used oral antihyperglycemic combination in clinical practice. Both medications present undesirable cardiovascular effects. The issue whether adverse effects of each these pharmacologic agents may be additive and detrimental to prognosis for coronary patients has not yet been specifically addressed.
PURPOSE: To investigate whether unenhanced dual-helical computed tomography (CT) is useful in the rapid, noninvasive detection of protruding aortic atheromas. MATERIALS AND METHODS: Thirty-two consecutive patients at least 50 years age who had recent ischemic stroke, systemic emboli, or both, underwent transesophageal echocardiography (TEE) and CT with thin sections (section thickness, 3.2 mm; reconstruction increment, 1.5 mm). RESULTS: TEE demonstrated atheromas 15 (47%); depicted 13 those...
Background: Development of insulin resistance (IR) may be important in the pathogenesis both metabolic syndrome and type 2 diabetes mellitus.Few data are available regarding short-term efficacy peroxisome proliferator-activated receptor ligand bezafibrate on IR, its long-term effect is unknown.The present analysis aimed to investigate IR patients with coronary artery disease enrolled Bezafibrate Infarction Prevention Study.Methods: Metabolic inflammatory parameters were analyzed from stored...
The authors have examined the usefulness of Dagens, Rasolt and Taylor (DRT) interionic potential (1975) for calculating disorder defect properties in Al from point view a molecular dynamics (MD) computer simulation. problem was complicated by strong long-range oscillations present careful attention paid to this detail. confirmed that low-temperature phonons generated MD program agreed very well with quasi-harmonic DRT then proceeded generate high-temperature phonons. They also calculated...
Type 2 diabetes mellitus (DM) is a frequent co-morbidity among patients undergoing coronary artery bypass grafting (CABG) surgery. The aim of this study was to evaluate the impact DM on early- and long-term outcomes who underwent isolated CABG. We performed an observational cohort in large tertiary medical center over period 11 years. All data from had undergone CABG surgery between 2004 2014 were obtained our departmental database. population included 2766 divided into two groups: Group I...
Prediabetes is a well-established risk factor for progression to overt diabetes mellitus (DM), which in turn associated with development of hypertension (HTN) and vice versa. However, the role prediabetes HbA1c particular as an independent unclear.In this current study, we aimed evaluate association between both fasting plasma glucose (FPG) hemoglobin A1c (HbA1c) levels range HTN among large cohort normotensive subjects.We investigated 5016 participants without DM other cardiovascular...
Data regarding long-term association of metabolic syndrome (MetS) with adverse outcomes are conflicting. We aim to determine the independent MetS (based on its different definitions) 20 year all-cause mortality among patients stable coronary artery disease (CAD).Our study comprised 15,524 who were enrolled in Bezafibrate Infarction Prevention registry between February 1, 1990, and October 31, 1992, subsequently followed-up for through December 2014. was defined according two definitions: The...
Aims To assess the effect of fibric acid derivative bezafibrate on incidence type 2 diabetes in obese patients over a median 6.3 years follow-up period.