A5009830085- Diabetes, Cardiovascular Risks, and Lipoproteins
- Blood Pressure and Hypertension Studies
- Natural Antidiabetic Agents Studies
- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Cardiovascular Health and Risk Factors
- Mosquito-borne diseases and control
- Global Public Health Policies and Epidemiology
- Nutritional Studies and Diet
- Pharmaceutical Practices and Patient Outcomes
- Antiplatelet Therapy and Cardiovascular Diseases
- Liver Disease Diagnosis and Treatment
- Sodium Intake and Health
- Cardiovascular Function and Risk Factors
- Cardiovascular and exercise physiology
- Photoacoustic and Ultrasonic Imaging
- Trace Elements in Health
- Advanced MRI Techniques and Applications
- Hemodynamic Monitoring and Therapy
- Heart Rate Variability and Autonomic Control
- Phytochemicals and Medicinal Plants
- Sepsis Diagnosis and Treatment
- Cardiac, Anesthesia and Surgical Outcomes
- Adipose Tissue and Metabolism
- Diabetes Management and Education
University of Colombo
2012-2023
Sri Lanka Foundation
2021-2022
University of Moratuwa
2014
National Hospital of Sri Lanka
2011-2013
Diabetes Australia
2008
Leeds General Infirmary
2004
British Heart Foundation
2004
Memorial Hospital
2004
St. Luke's Episcopal Hospital
2004
Abstract Aims To determine the prevalence of diabetes mellitus and pre‐diabetes (impaired fasting glucose impaired tolerance) in adults Sri Lanka. Projections for year 2030 factors associated with are also presented. Methods This cross‐sectional study was conducted between 2005 2006. A nationally representative sample 5000 aged ≥ 18 years selected by a multi‐stage random cluster sampling technique. Fasting plasma tested all participants 75‐g oral tolerance test performed non‐diabetic...
Prevalence of diabetes mellitus (DM) has reached epidemic proportions in Sri Lanka. Presently there are studies on the community prevalence distal peripheral neuropathy (DPN) We describe prevalence, patterns and predictors DPN patients with DM Data were collected as part a national study DM. In new cases was assessed using Diabetic-Neuropathy-Symptom (DNS) score, while those established both DNS Toronto-Clinical-Scoring-System (TCSS) used. A binary logistic-regression analysis performed...
Summary The aim of the study was to determine prevalence overweight, obesity and abdominal obesity, underlying socio‐demographic correlates among Sri Lankan adults. Data were from 4532 adults aged ≥18 years randomly selected for a national level on diabetes cardiovascular disease. Weight, height waist circumference (WC) measured body mass index (BMI) calculated. mean (95% confidence interval) BMI WC 21.1 kg m −2 (20.9–21.3), 22.3 (22.1–22.4) 78.0 cm (77.5–78.6) 77.5 (77.0–78.0) males...
Abstract Background This study evaluated the effects of zinc supplementation on glycemic control, other cardiometabolic and anthropometric parameters, disease progression in prediabetes. Methods A randomized double‐blind placebo‐controlled Phase 2 clinical trial was conducted over a 12‐month period 200 subjects (43% male; mean [± SD] age 51.8 ± 7.3 years), randomly assigned (1: 1) to treatment or control group. The group received (20 mg daily). Subjects were at baseline 1, 3, 6, 12 months....
Cinnamon is considered as a treatment for many ailments in native medicine. Evidence suggests that Cinnamomum zeylanicum (CZ) has anti-microbial, anti-parasitic, anti-oxidant, blood glucose lowering properties and beneficial cardiovascular effects. The present study aims to evaluate Pharmacodynamic safety of CZ healthy adults using Phase I Clinical Trial. This phase clinical trial was conducted at the Department Pharmacology, Faculty Medicine, University Colombo, Sri Lanka. Thirty were...
We studied the community prevalence, patterns and predictors of hypertension in a large sub-population South Asian adults with view identifying differential risk factors. Data were collected between years 2005–2006 5000 invited for study. The sample size was 4485, about 39.5% males. Mean systolic diastolic blood pressures 127.1 ± 19.8 mmHg 75.4 11.3 mmHg, respectively. Age-adjusted prevalence all adults, males females 23.7%, 23.4% 23.8%, Urban had significantly higher than rural adults. In...
Previous studies have explored the anti-diabetic effects of Cinnamomum cassia extract in vivo and vitro. However, there are no at present exploring indigenous species Sri Lankan cinnamon (Cinnamomum zeylanicum) patients with diabetes mellitus. The study aims to evaluate potential zeylanicum as a pharmaceutical agent type-2 will be conducted randomized, double-blind, placebo-controlled clinical trial for period 4 months Medical Clinic, University Unit, National Hospital Lanka. A total 210...
Abstract Background Patients’ knowledge on prescribed medications play a key role in the long term management of cardiac diseases and determining their outcome. The present study evaluates about medication among patients aim to identify factors influencing knowledge. Methods A descriptive-cross-sectional was conducted 200 adult attending clinics at Cardiology Unit National Hospital Sri Lanka. Knowledge assessment focused four different sections; drug name, dose, frequency indication. total...
The use of computer assisted learning (CAL) has enhanced undergraduate medical education. CAL improves performance at examinations, develops problem solving skills and increases student satisfaction. study evaluates literacy among first year students in Sri Lanka. was conducted Faculty Medicine, University Colombo, Lanka between August-September 2008. First (n = 190) were invited for the study. Data on associated factors collected by an expert-validated pre-tested self-administered...
Objectives: This study aimed to determine the prevalence and underlying sociodemographic correlates of smoking among Sri Lankans. Methods: A cross-sectional sample (N = 5000, age >18 years) was selected using a multistage random cluster sampling. Data were collected an interviewer-administered questionnaire. Results: Response rate 91% (n 4532); males 40%; mean 46.1 years (±15.1). Overall, urban rural current (smoking) 18.3%, 17.2%, 18.5%, respectively ( P nonsignificant, vs rural)....
To study the prevalence and define deferential risk factors for 'Resistant' hypertension (RHT) in a hypertensive population of South Asian origin.A descriptive cross-sectional was carried out among patients attending clinics at Cardiology Unit, Colombo from July-October 2009. All with who provided informed written consent were recruited to (n = 277). A pre-tested interviewer-administered questionnaire used data collection. binary logistic-regression analysis performed all 'presence RHT' as...
Abstract Sri Lankan inpatients receive a discharge summary in English known as diagnosis card. The authors investigated whether supplementing the with native language improved patients' knowledge of illness and medication. Participants were 130 newly diagnosed patients noncommunicable chronic diseases (92 men, 70.8%; 38 women, 29.2%; M age = 55.4 years, SD 12.8 years) who randomized to control group receiving an intervention supplementary summary. A questionnaire assessed prescribed...
Dengue hemorrhagic fever (DHF) is a major cause of morbidity and mortality in tropical regions. Serum free calcium (Ca2+) known to be important cardiac circulatory function. We evaluated association between serum Ca2+ level severity dengue.A cross-sectional study was carried out at tertiary care private hospital Sri Lanka. A probable case dengue diagnosed classified according World Health Organization criteria confirmed by either IgM antibody, PCR, or NS1 antigen detection. Socio-demographic...
Abstract We evaluated the effectiveness of MEWS and biochemical parameters in predicting outcomes for acute medical admissions. Data from consecutive admissions to Acute Medical Unit (AMU) National Hospital Sri Lanka were collected. C-reactive protein (CRP), albumin, white cell count, platelet count haemoglobin values Adverse endpoints HDU/ICU admission, cardio-respiratory emergency/resuscitation death. A score >=5 together with increasing age, pulse rate, respiratory AVPU score, CRP,...