A5000646725- Amyotrophic Lateral Sclerosis Research
- Nerve injury and regeneration
- Neurogenetic and Muscular Disorders Research
- BRCA gene mutations in cancer
- Pharmaceutical studies and practices
- Genomics and Rare Diseases
- Hormonal Regulation and Hypertension
- Diabetes Treatment and Management
- Blood Pressure and Hypertension Studies
- Neuroendocrine Tumor Research Advances
- Neurogenesis and neuroplasticity mechanisms
- Drug Transport and Resistance Mechanisms
- Genetic Neurodegenerative Diseases
- Pharmacogenetics and Drug Metabolism
- Cancer Genomics and Diagnostics
- Adenosine and Purinergic Signaling
- Renal Diseases and Glomerulopathies
Indiana University School of Medicine
2018-2024
Indiana University – Purdue University Indianapolis
2018-2024
Virginia Commonwealth University
2018
University Health System
2018
The University of Texas MD Anderson Cancer Center
2018
Hypertension and chronic kidney disease are inextricably linked. is a well-recognized contributor to progression and, in turn, renal potentiates hypertension. A generalized approach drug selection dosage has not proven effective managing these conditions, part, because patients with heterogeneous hypertension etiologies frequently grouped according functional or severity classifications. Genetic testing may serve as an important tool the armamentarium of clinicians who embrace precision...
To validate a laboratory-developed test for the nucleoside transporter, SLC28A3, which has been associated with an increased risk of anthracycline-induced cardiomyopathy.We used Taqman® allele discrimination to two variants SLC28A3 gene: rs7853758 (c.1381C>T) and rs885004 (c.862-360C>T).During validation process, we noted that several DNA samples obtained from Coriell Cell Repository (Camden, NJ) were positive both c.1381 C > T c.862-360C>T another variant either or (e.g., c.1381C>T...
Introduction Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease characterized by progressively worsening motor symptoms that lead to eventual fatal paralysis. The number of gene mutations associated with ALS have increased dramatically in recent years, suggesting heterogeneity the etiology and need develop new models encompass these pathologies. In 2011, UBQLN2 were identified families both frontotemporal dementia (FTD) since been linked ubiquitinated TDP43...