- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Synthesis and Catalytic Reactions
- Asymmetric Hydrogenation and Catalysis
- Asymmetric Synthesis and Catalysis
- CO2 Reduction Techniques and Catalysts
- Bone and Dental Protein Studies
- Fibroblast Growth Factor Research
- RNA modifications and cancer
- Sulfur-Based Synthesis Techniques
- Extracellular vesicles in disease
- Spine and Intervertebral Disc Pathology
- Spondyloarthritis Studies and Treatments
- Cancer Research and Treatments
- Hip disorders and treatments
- Plant Pathogens and Fungal Diseases
- Nanoparticle-Based Drug Delivery
- Crystallography and molecular interactions
- Horticultural and Viticultural Research
- Nanoplatforms for cancer theranostics
- Radical Photochemical Reactions
- Catalytic C–H Functionalization Methods
- Fermentation and Sensory Analysis
Pfizer (United States)
2022-2024
The University of Melbourne
2024
KU Leuven
2024
Hospital Piñero
2021
University of California, Davis
2019
A useful protocol for achieving decarboxylative cross-coupling (DCC) of redox-active esters (RAE, isolated or generated in situ) and halo(hetero)arenes is reported. This pragmatically focused study employs a unique Ag-Ni electrocatalytic platform to overcome numerous limitations that have plagued this strategically powerful transformation. In its optimized form, coupling partners can be combined surprisingly simple way: open the air, using technical-grade solvents, an inexpensive ligand Ni...
Diastereoselective Lewis acid-mediated additions of nucleophilic alkenes to N-sulfonyl imines are reported. The canonical polar Felkin-Anh model describing carbonyls does not adequately describe analogous imines. Herein, we the development conditions produce both syn and anti products with high diastereoselectivity good yields. A stereoelectronic consistent experimental outcomes is also proposed.
Increasingly complex, three-dimensional leads for drug discovery are testing the limits of modern organic synthesis. In this context, need new methods to access gem-diarylated cyclobutanes, azetidines, and oxetanes is apparent. The present study outlines a modular, scalable, chemoselective approach solve problem using simple a-bromoacids aryl halides as intuitive starting materials. As demonstrated herein, sequential series Ni-electrocatalytic cross-couplings can be enlisted enable rapid...
Introducción: La espondilitis anquilosante es un trastorno inflamatorio progresivo que afecta el esqueleto axial, inclusive las articulaciones sacroilíacas; riesgo de sufrir una fractura se cuadruplica (10% a los 10 años enfermedad), la tasa demora del diagnóstico alta. rigidez y osteoporosis son factores clave para estas lesiones. tomografía computarizada resonancia magnética cumplen rol fundamental. descompresión fijación quirúrgica tratamiento elección actual. Se presenta serie casos con...
ISHS International Symposium on Viticulture and Enology INFLUENCE OF DIFFERENT FERMENTATION CONDITIONS ON THE PRODUCTION MEDIUM CHAIN FATTY ACIDS (C6,C8,C10) AND THEIR RESPECTIVE ETHYL ESTERS BY SACCHAROMYCES CEREVISIAE