- Ethnobotanical and Medicinal Plants Studies
- Drug-Induced Hepatotoxicity and Protection
- Natural Antidiabetic Agents Studies
- Phytochemistry and Biological Activities
- Natural product bioactivities and synthesis
- Cardiac Ischemia and Reperfusion
- Parasitic Diseases Research and Treatment
- Insect Pest Control Strategies
- Insect Utilization and Effects
- Traditional Chinese Medicine Analysis
- Medicinal Plants and Neuroprotection
- Phytochemicals and Medicinal Plants
- Helminth infection and control
- Biomedical and Engineering Education
- Polyamine Metabolism and Applications
- Pomegranate: compositions and health benefits
- Trypanosoma species research and implications
- Pneumonia and Respiratory Infections
- Phytochemistry and biological activities of Ficus species
- Nematode management and characterization studies
- Medicinal Plant Extracts Effects
- Mast cells and histamine
- Problem and Project Based Learning
- Bioactive Compounds and Antitumor Agents
- Beetle Biology and Toxicology Studies
Aligarh Muslim University
2008-2024
Jawaharlal Nehru Medical College Hospital
2010-2024
Jawaharlal Nehru Medical College
2014-2024
Albizzia lebbeck Benth. (Mimosaceae) is a medicinal tree used to treat several inflammatory ailments in the Indian traditional Ayurvedic system of medicine. The aim present study was evaluate possible anti-inflammatory activity aqueous (AE) and ethanolic (EE) extracts leaves A. support ethnopharmacological claims. carried out using Wistar rats (100–150 g). AE EE were prepared Soxhlet extraction process. studied carrageenan-induced paw edema cotton pellet-induced granuloma models. at doses...
Ischemic injury during myocardial infarction (MI) is responsible for increased deaths among patients with cardiovascular disorders. Recently, research has been directed finding treatment using natural compounds. This study was performed to investigate the effects of syrigaldehyde (SYD), a phytochemical against isoproterenol (ISO) induced cardiotoxicity model.For induction MI, rats were intoxicated two doses ISO and treated SYD at three different concentrations (12.5, 25 & 50 mg/kg) both...
Cichorium intybus L. commonly known as chicory is one of the important medicinal plants used in Ayurvedic system medicine. It for treatment diseases involving a khapa and pitta doshas. Traditionally, C. inflammatory conditions, but there are only few vitro studies reporting anti-inflammatory activity roots chicory.Evaluation mechanisms involved it using vivo models inflammation.Albino Wistar rats either sex weighing 150-200 g were used. Ethanolic aqueous extracts prepared with help Soxhlet's...
Our objective was to evaluate the analgesic and anti-inflammatory activity of aqueous ethanolic extracts Cuminum cyminum L. ( C. ) seeds. Aqueous seeds were prepared using Soxhlet apparatus. Acute toxicity study performed as per OECD-425 Guidelines doses 200 mg/kg 500 each extract selected. Swiss Albino mice used for Acetic-acid induced writhing method Wistar rats Eddy's hot plate, Carrageenan-induced paw oedema Cotton-pellet granuloma methods. The animals divided into 6 groups (n = 6)....
Ethnopharmacological relevance: Mallotus phillipensis (MP) belongs to the endangered plants of great medicinal value. Widely used in Ayurvedic healthcare system, parts plant which are rich secondary metabolites treatment several diseases like eczema, bronchitis, worm infestation, diabetes, kidney stones, cancer, and malaria. In ethnomedicine, MP has been reported be traditionally healing jaundice inflammatory conditions Ayurveda system. This was thus selected explore its hepatoprotective...
Background: Drugs for liver ailments have been important in research, but still the number of drugs acting on various hepatic diseases is very limited. This study, first time, evaluates hepatoprotective activity aqueous extract roots Valeriana Wallichii albino rats. Methods: The hepatotoxicity was induced by CCl 4 . Animals were divided into 5 groups 6 animals each. Group I (Normal control) given only distilled water. II (Negative control)was administered 7 days while III (Positive silymarin...
Aim- To evaluate the analgesic activity of aqueous and ethanolic extracts Coriandrum sativum (C. sativum) seeds by thermal pain stimulus. Materials & methods- After an acute toxicity study performed as per OECD-425 Guidelines, doses 100 mg/kg, 250 mg/kg 500 each extract were selected. Wistar albino rats either sex (100-200 g) tested for mean response time Eddy’s hot plate method. Statistical significance (p<0.05) was analyzed using ANOVA with post-hoc Dunnett’s test. Results- Both...
Abstract Albizia lebbeck Benth. is extensively used in Indian traditional medicine for treating several painful and inflammatory disorders. The possible central analgesic activity the underlying mechanism of action aqueous (AE) ethanolic extracts (EE) leaves A . were investigated Wistar rats using Eddy’s hot plate tail flick tests. In order to investigate action, pretreated with naloxone, bicuculline or methysergide then administered a per os (p.o.) dose AE EE. EE caused significant...
The study was conducted to screen the heptoprotective activity of fractions Fumaria parviflora (F. parviflora) and underlying mechanisms by using in vivo model hepatotoxicity. Albino rats either sex weighing 200 - 250 g were taken. Methanol ethyl acetate used as test compounds study. hepatotoxicity induced administration antitubercular drugs (Isoniazid 7.5 mg/kg, Rifampicin 10 mg/kg Pyrazinamide 35 body weight rat). Both (300 & 500 mg/kg) inducing agent given for days per orum. sacrificed,...
The aqueous extract of Bark Plumeria. alba was tested for its effect on the spontaneous movements whole worm (w.w) preparation and nerve muscle (n.m) complex Setaria cervi a cattle filarial parasite, survival microfilariae . could inhibit S.cervi, characterized by initial stimulation followed reversible paralysis. concentration required to produce similar less as compared worm. lethal 50 (LC50) 90 (LC90) were 80 ng/ml 105 respectively.
Objective: To screen the potential antifilarial activity of petroleum and alcoholic extracts prepared from fruit Diospyros montana . Materials Methods: In vitro study was carried out to see effect on both whole worm(w.w). preparation nerve muscle (n.m) Setaria cervi , survival microfilariae. Results: Petroleum extract produced initial stimulation followed by reversible paralysis in worm The is not seen with preparation. caused whereas irreversible Conclusion: Fruit D. found possess activity.
Pharmacology is one of the most active branches medicine with respect to amount research and innovation. The field pharmacology actively involved in new drug discovery identification therapeutic targets. However, unfortunately, same cannot be said for medical departments various colleges India abroad.