A5056282324- Sarcoma Diagnosis and Treatment
- Oral and Maxillofacial Pathology
- Cancer and Skin Lesions
- Bone Tumor Diagnosis and Treatments
- Diagnosis and treatment of tuberculosis
- Ovarian cancer diagnosis and treatment
- Infectious Diseases and Tuberculosis
- Breast Lesions and Carcinomas
- Photodynamic Therapy Research Studies
- Tumors and Oncological Cases
- Soft tissue tumor case studies
- Endometrial and Cervical Cancer Treatments
- Cancer Diagnosis and Treatment
- Salivary Gland Tumors Diagnosis and Treatment
- Nanoplatforms for cancer theranostics
- Neurofibromatosis and Schwannoma Cases
- Intraperitoneal and Appendiceal Malignancies
- Ear and Head Tumors
- Urologic and reproductive health conditions
- Cancer Cells and Metastasis
- Breast Cancer Treatment Studies
- Cervical Cancer and HPV Research
- Genital Health and Disease
- Medical Imaging and Pathology Studies
- Vascular Tumors and Angiosarcomas
Aligarh Muslim University
2016-2025
Jawaharlal Nehru Medical College Hospital
2016-2025
Creative Commons
2023
The Rotherham NHS Foundation Trust
2022
Jawaharlal Nehru Medical College
2012-2020
Jawaharlal Nehru Medical College
2017-2020
Sarojini Naidu Medical College
2008-2012
King Khalid University
2010
B. J. Medical College & Sassoon Hospital
2008
The "one drug-one target" paradigm has various limitations affecting drug efficacy, such as resistance profiles and adverse effects. Combinational therapies help reduce unexpected off-target effects accelerate therapeutic efficacy. Sorafenib- an FDA-approved for liver cancer, multiple limitations. Therefore, it is recommended to identify agent that increases its effectiveness reduces toxicity. In this regard, Apigenin, a plant flavone, would be excellent option explore.
To evaluate the effect of allagic acid treatment on cell viability human prostate cancer cells. Ellagic (10-100 mol/L) (48 h) carcinoma PC3 cells was found to result in a dose-dependent inhibition growth and apoptosis as assessed by MTT assay, western blotting, flow cytometry confocal microscopy. We observed that ellagic resulted dose dependent growth/cell viability. This caused be accompanied induction apoptosis, cleavage poly (ADP-ribose) polymerase (PARP) morphological changes. Further,...
Morbidity and mortality due to oral cancer in India are exacerbated by a lack of access effective treatments amongst medically underserved populations. We developed user-friendly low-cost, portable fibre-coupled LED system for photodynamic therapy (PDT) early lesions, using smartphone fluorescence imaging device treatment guidance, 3D printed fibreoptic attachments ergonomic intraoral light delivery.
Ischemic injury during myocardial infarction (MI) is responsible for increased deaths among patients with cardiovascular disorders. Recently, research has been directed finding treatment using natural compounds. This study was performed to investigate the effects of syrigaldehyde (SYD), a phytochemical against isoproterenol (ISO) induced cardiotoxicity model.For induction MI, rats were intoxicated two doses ISO and treated SYD at three different concentrations (12.5, 25 & 50 mg/kg) both...
Cichorium intybus L. commonly known as chicory is one of the important medicinal plants used in Ayurvedic system medicine. It for treatment diseases involving a khapa and pitta doshas. Traditionally, C. inflammatory conditions, but there are only few vitro studies reporting anti-inflammatory activity roots chicory.Evaluation mechanisms involved it using vivo models inflammation.Albino Wistar rats either sex weighing 150-200 g were used. Ethanolic aqueous extracts prepared with help Soxhlet's...
Abstract Diabetic foot infection caused by multidrug-resistant bacteria, is becoming serious problem. Moreover, polymicrobial biofilms contribute significantly to the persistent infections. In present study, we investigated effectiveness of novel toluidine blue conjugated chitosan coated gold–silver core–shell nanoparticles (TBO–chit–Au–AgNPs) mediated photodynamic therapy and demonstrate their use as a nontoxic antibacterial combat diabetic ulcer (DFU) multi-drug resistant strains both in...
India has one of the highest rates oral squamous cell carcinoma (OSCC) in world, with an incidence 15 per 100,000 and more than 70,000 deaths year. The problem is exacerbated by a lack medical infrastructure routine screening, especially rural areas. New technologies for cancer detection timely treatment at point care are urgently needed.
Significance: India has one of the highest rates oral cancer incidence in world, accounting for 30% reported cancers. In rural areas, a lack adequate medical infrastructure contributes to unchecked disease progression and dismal mortality rates. Photodynamic therapy (PDT) emerged as an effective modality with potential treating early stage resource-limited settings, while photosensitizer fluorescence can be leveraged treatment guidance. Aim: Our aim was assess capability simple...
The study was undertaken to evaluate liquid based cytology (Pap spin) and compare the sensitivity of Pap spin with conventional smear. smears were taken from 160 patients gynaecologic complaints Ayre's spatula endocervical cytobrush slides prepared. residual material on both rinsed in collection fluid centrifuged. Direct prepared cell button, fixed stained by Papanicolaou stain. Colposcopy performed abnormal biopsy suspected malignant or dysplastic cases. LSIL HSIL diagnosed 27 (64.4%)...
Androgen deprivation therapy is commonly used for the treatment of prostate cancer. Enzalutamide a next-generation androgen receptor inhibitor, initially approved to treat castration-resistance Lupeol, triterpene present in various fruits, vegetables, has anti-oxidant and anti-proliferative activity. The study aimed evaluate Enzalutamide-induced toxicity its possible amelioration by Lupeol. We performed multiple vitro vivo experiments conclude our hypothesis. results revealed that both...
The present study aimed to evaluate the histologic, histochemical, and immunohistochemical changes in buffalo livers with cystic echinococcosis. Noninfected infected were collected from freshly slaughtered at Aligarh abattoir. Small pieces of both noninfected (
Abstract Background and Aim: The International System for Reporting Serous Fluid Cytopathology was designed to standardize the reporting of serous fluid cytology, which we have applied cytology in present study. Materials Methods: This retrospective study conducted Department Pathology, Jawaharlal Nehru Medical College, Aligarh Muslim University, from February 1 st , 2021, March 31 2023, on 966 cytospin smears body cavity fluids pleural, peritoneal, pericardial cavity. effusion findings were...
Alveolar ridge preservation (ARP) limits dimensional changes in alveolar bone after extraction. This study aims to evaluate tissue response biphasic-calcium-phosphate ceramics (BCP) with different hydration methodologies used for ARP. Sixty patients willing treatment were randomly allocated into two test groups and control. Test group-1 (n = 20) received graft hydrated saline ARP, whereas group-2 blood. In control 20), extraction sockets allowed heal without further intervention. Clinically...
Aims: This study evaluates the risk of endometrial carcinoma in postmenopausal women presenting with bleeding using an ultrasound-based scoring system. It aims to integrate imaging parameters and clinical variables for improved differentiation between benign malignant conditions. Methods: A prospective analysis was conducted on per vagina. Clinical including age, parity, BMI, hypertension, diabetes were combined ultrasound findings such as thickness, echogenicity, endo-myometrial interface,...
Sister Mary Joseph’s nodule is identified by detectable lumps that extend into the umbilicus due to spread of cancer from abdominal or pelvic regions. Commonly, these cancers originate gastrointestinal genital areas, but other sources are rare. Our case involved a 27-year-old female who came with an umbilical swelling bilateral adnexal growth. Laboratory, radiological, and histopathological examinations led diagnosis adenocarcinoma ovary, metastasis umbilicus. To our knowledge, this rare...
Gallbladder carcinoma (GBC) is the most common malignant tumor of biliary system and presents with frequent locoregional lymphadenopathy distant metastasis. tuberculosis (GT) rare abdominal (TB). GBC GT mimic each other. The clinical examinations radiographic investigations sometimes fail to exhibit difference between these two which are confirmed only after postoperative histopathological assessment. Herein, we report a patient coexistent pleural metastasis effusion. We emphasize importance...