Zaleha Abdullah Mahdy

ORCID: 0000-0003-0856-0697
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About
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Research Areas
  • Pregnancy and preeclampsia studies
  • Gestational Diabetes Research and Management
  • Birth, Development, and Health
  • Maternal and Perinatal Health Interventions
  • Maternal and fetal healthcare
  • Neonatal Respiratory Health Research
  • Global Maternal and Child Health
  • Pregnancy-related medical research
  • Assisted Reproductive Technology and Twin Pregnancy
  • Nutritional Studies and Diet
  • Iron Metabolism and Disorders
  • Hematopoietic Stem Cell Transplantation
  • COVID-19 Impact on Reproduction
  • Sexual Differentiation and Disorders
  • Child Nutrition and Water Access
  • Preterm Birth and Chorioamnionitis
  • Neonatal and fetal brain pathology
  • Maternal Mental Health During Pregnancy and Postpartum
  • Endometriosis Research and Treatment
  • Ectopic Pregnancy Diagnosis and Management
  • Mesenchymal stem cell research
  • Bariatric Surgery and Outcomes
  • Reproductive System and Pregnancy
  • Menstrual Health and Disorders
  • Prenatal Screening and Diagnostics

National University of Malaysia
2013-2025

University Kebangsaan Malaysia Medical Centre
2014-2024

Hospital Kuala Lumpur
2006-2023

Newcastle University Medicine Malaysia
2023

Monash University Malaysia
2023

Jabatan Perkhidmatan Awam Malaysia
2020

University Medical Center Utrecht
2017

Newcastle University
1996

Nitric oxide (NO), produced by endothelial nitric synthase (eNOS), is a major antiatherogenic factor in the blood vessel. Oxidative stress plays an important role pathogenesis of various cardiovascular diseases, including atherosclerosis. Decreased availability NO promotes progression dysfunction and Rutin flavonoid with multiple protective effects. This study aimed to investigate effects rutin on eNOS production cultured human umbilical vein cells (HUVEC). HUVEC were divided into four...

10.1155/2014/169370 article EN cc-by The Scientific World JOURNAL 2014-01-01

In Islam, the person with somatic sex ambiguity due to a disorder of development (DSD), such as 46,XX congenital adrenal hyperplasia or 46,XY androgen insensitivity, is recognized khunsa. Two types khunsa are distinguished: wadhih (discernible) and musykil (intractable). A recent fatwa (religious edict) in Malaysia decreed that it permissible for male-assigned patients from these two groups have gender reassignment surgery female following diagnosis; however, religious authority has yet rule...

10.1007/s10508-016-0754-y article EN cc-by Archives of Sexual Behavior 2016-04-21

Purpose This study aims to evaluate the effectiveness of intralesional bleomycin sclerotherapy in treatment lymphangioma children and determine incidence complications treatment. Methods is a retrospective 24 diagnosed with treated injection aqueous solution from January 1999 December 2004. Results Complete resolution was seen 63% (15/24) lesions, 21% (5/24) had good response 16% (4/24) poor response. The tumour recurred 2 patients. Two other patients abscess formation at site injection. No...

10.2349/biij.7.3.e18 article EN Biomedical Imaging and Intervention Journal 2011-07-01

Background Gestational diabetes mellitus (GDM) is a common medical complication in pregnancy. The aim of this study was to compare the prevalence GDM using World Health Organization (WHO) criteria and International Association Diabetes Pregnancy Study Group (IADPSG) our population. We further compared incidence adverse maternal neonatal outcomes women diagnosed with these determined whether IADPSG suitable Methods This randomized controlled trial conducted at antenatal clinic involving 520...

10.1515/hmbci-2017-0077 article EN Hormone Molecular Biology and Clinical Investigation 2018-02-17

Medical transportation is an essential step in health care services, and includes ground, air water transportation. Among the important uses of medical delivery blood products event a clinical emergency. Drone technology latest technological advancement that may revolutionize globally. Nonetheless, its economic evaluation scant insufficient, whilst cost-effectiveness remains controversial. The aim this study was to compare drone versus ambulance.The setting within developing nation. An...

10.1186/s12913-021-07321-3 article EN cc-by BMC Health Services Research 2021-12-01

The lack of standardized clinical practice impeding the optimal management iron deficiency (ID) and anemia (IDA) in women is a global concern, particularly Asia-Pacific region. aim this study was to determine best practices through Delphi consensus process. In Round 1, panelists were asked rate their level agreement with 99 statements across four domains: identification, diagnosis assessment, prevention, treatment ID/IDA women. 2, reappraised ratings view collective feedback responses 1....

10.3390/nu15143125 article EN Nutrients 2023-07-13

BACKGROUND: This trial aimed to assess the efficacy, acceptability, and safety of a first-trimester screen-and-prevent strategy for preterm preeclampsia in Asia. METHODS: Between August 1, 2019, February 28, 2022, this multicenter stepped wedge cluster randomized included maternity/diagnostic units from 10 regions The started with period where all recruiting centers provided routine antenatal care without study-related intervention. At regular 6-week intervals, one was transit...

10.1161/circulationaha.124.069907 article EN Circulation 2024-06-26

To determine obstetric and neonatal risk factors associated with subaponeurotic haemorrhage (SAH) in infants exposed to vacuum extraction.A prospective observational study.In the labour room, operation theatre, postnatal wards intensive care unit (NICU) of a tertiary teaching hospital.All born hospital history exposure study carried out over 26-month period. All eligible were examined at birth during first 24 hours life.A diagnosis SAH was based on detection tender fluctuant scalp swelling...

10.1111/j.1471-0528.2005.00732.x article EN BJOG An International Journal of Obstetrics & Gynaecology 2005-09-22

Pregnant women form one of the high risk groups facing hypovitaminosis D. Low level vitamin D will affect directly or indirectly both mother and fetus. Screening in first trimester pregnancy is important to determine necessary preventive action. Therefore, this study was aimed prevalence its factors among pregnant trimester.A cross sectional carried out during their antenatal visit. Samples were taken from different ethnicities an urban district Malaysia. A total 396 respondents (99 %...

10.1186/s12884-016-0939-3 article EN cc-by BMC Pregnancy and Childbirth 2016-07-13

Background Preeclampsia is associated with an increased risk of adverse maternal and perinatal outcomes. This study aimed to assess preeclampsia prevalence in a Malaysian referral maternity hospital the association between characteristics Methods A cross-sectional was conducted January 2010 December 2020 using secondary data from single tertiary healthcare center Greater Kuala Lumpur, Malaysia. total 40,212 deliveries were included for analysis investigate conditions (maternal birth...

10.3389/fpubh.2022.973271 article EN cc-by Frontiers in Public Health 2022-10-17

Preeclampsia is a syndrome that continues to be major contributor maternal and neonatal mortality, especially in low-income countries. Low-dose aspirin reduces the risk of preeclampsia, but mechanism still unknown. Risk factors identify women at preeclampsia are based on clinical characteristics. Women identified as high-risk would benefit from treatment initiated, preferably end first trimester. Current efforts have largely focused developing screening algorithms incorporate factors,...

10.1016/j.xagr.2024.100352 article EN cc-by AJOG Global Reports 2024-04-03

Pregnant women are susceptible to COVID-19 complications due gestation-related physiological changes. We aimed evaluate the level of maternal knowledge, perception, and practice during pandemic. A cross-sectional study was conducted Malaysian Movement Control Order (MCO) between April June 2020. self-administered electronic questionnaire that included knowledge domains distributed. newly designed set questions used (1) women’s perception MCO (2) experience, which subdivided into clinical...

10.3390/ijerph18115762 article EN International Journal of Environmental Research and Public Health 2021-05-27

Abstract Aim: To compare the success, clinical outcomes, and maternal neonatal complications between Kiwi Omnicup Malmstrom metal cup in vacuum assisted delivery. Methods: This was a prospective randomized comparative trial. Women who required vaginal delivery were into (KO) group (MM) group. The deliveries conducted according to hospital protocol. Details of procedure outcomes including success analyzed. Results: One hundred sixty‐four women recruited – 85 assigned using KO 79 MM. percent...

10.1111/j.1447-0756.2007.00701.x article EN Journal of Obstetrics and Gynaecology Research 2008-01-23
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