<title>Abstract</title> The symbiotic skin bacterium <italic>Staphylococcus epidermidis</italic> moisturizes human skin, helps protect the body from external pathogens, and contributes to stimulation of innate immune system. However, relationship between major protein collagen <italic>S. has not been studied extensively. Here, I observed development biofilms using scanning electron microscopy with an ionic liquid sample pretreatment technique; were formed on a carbon-coated...

The threat of antibiotic-resistent biofilms demands solutions. Silver-coated azithromycin-Soluplus nanoparticles release silver ions for 6+ hours, disrupt biofilms, and enable rapid, sensitive bacterial detection with laser-induced graphene sensors.

Journal Article Observation of antibacterial effect biodegradable polymeric nanoparticles on Staphylococcus epidermidis biofilm using FE-SEM with an ionic liquid Get access Chisato Takahashi, Takahashi * School Pharmacy, Pharmaceutical Engineering, Aichi Gakuin University, 1-100, Kusumoto-cho, Chikusa-ku, Nagoya, 464-8650, Japan *To whom correspondence should be addressed. E-mail: chisato@dpc.agu.ac.jp Search for other works by this author on: Oxford Academic PubMed Google Scholar Noriko...

We have successfully prepared polymeric micelles based on polyvinyl caprolactam–polyvinyl acetate–polyethylene glycol graft copolymer (Soluplus®) for a drug delivery system biofilm.

Antimicrobial peptides are potential molecules for the development of novel antibiotic agents. The ZorO toxin a type I toxin–antitoxin system in Escherichia coli O157:H7 is composed 29 amino acids and its endogenous expression inhibits E. growth. However, little known about inhibitory mechanism. In this study, we demonstrate that localized inner membrane affects plasma integrity when expressed cells, which triggers production cytotoxic hydroxyl radicals. We further show five internal...

Silver nanoparticles exert high antibacterial activity and thus have been used in polymeric formulations for drug delivery. In recent years, containing silver found to be highly effective against biofilm infections, which are difficult treat with drugs only. However, the effects of polymer composites depending on administration time still unknown. this study, we transmission electron microscopy investigate decorated poly(dl-lactide-

We developed a standard-free method for untreated hairs and the has been applied to quantitative analysis of more than 30,000 taken from people concerned in order evaluate exposure some toxic elements intakes essential elements. Besides these analyses, we have measured nearly 2000 collected healthy Japan over past 20 years. It was found that concentrations elements, such as vanadium, chromium, manganese, copper mercury, keep increasing up present. Such tendencies were particularly notable...

A standard-free method for untreated hairs has been applied to quantitative analysis of the taken from 1256 healthy people living in Iwate prefecture, Japan. It was found that there are clear sex-specific differences concentration some elements. Concentrations many essential elements, such as calcium, magnesium, iron, copper, zinc and bromine, clearly higher female. In particular, calcium is 2.6 times female comparison with male. Contrarily, concentrations toxic elements chromium, arsenic...

A gigantic tsunami following Tohoku-Earthquake Disaster brought a large amount of sludge, which originated from the sediments pilling upon bottom sea to residential areas. As it is anticipated that sludge contains heavy toxic elements, its influence on health suffered people will become problem. In present study, 72 samples were taken stricken areas by over wide area; (Aomori, Iwate and Miyagi prefectures). These treated basis powdered-internal-standard method analyzed means PIXE with...

National Institute of Advanced Industrial Science and Technology is working for the Global Alliance to Eliminate Lead Paint (GAELP) United Nations Environment Program (UNEP), under cooperation Iwate Medical University Cyclotron Center Nishina Memorial Japan Radioisotope Association. In order demonstrate how PIXE useful monitor lead in human body, hair samples were collected from local communities analyzed by at together with control office workers. The analysis showed a clear anomaly factory...

We developed and reported standard-free methods for various bio-samples in both invacuum in-air PIXE they have been applied to quantitative analyses of traces whose weights are less than 0.1 mg. In this study, we established a method analysis nearly [Formula: see text] in-vacuum PIXE. order improve sensitivity accuracy smaller samples on the basis method, which makes use continuous X-rays emitted from sample, it is essential design appropriate backing materials supporting sample. present...

This paper presents some experimental results which demonstrate restraint of fatigue crack growth in an Al–Mg alloy by wedge effects fine particles. Fatigue test specimens were machined from a JIS A5083P‐O plate 5 mm thickness and EDM starter notch was introduced to each specimen. Three kinds particles prepared as the materials be wedged into cracks, i.e. magnetic two alumina having different mean particle sizes 47.3 μm 15.2 μm. Particles kind suspended oil form paste, applied on specimen...

A standard-free method for living plants in in-air PIXE has been developed order to clarify the mechanism of elemental transportation and movement farm products. The components continuous X-rays originated from air a backing film can be exactly subtracted using blank spectrum after normalization by yields Ar K α X-rays. It is found observing yield with passage time that water content continuously decreasing during irradiation proton beam case pinched leaves. In contrary, it kept almost...

The method of quantitative analysis oil samples in in-air PIXE has been developed on the basis a standard-free method. components continuous X-rays originated from air and backing film can be exactly subtracted using blank spectrum after normalization by yields Ar K -α X-rays. was nine including standard oils its accuracy confirmed comparing results with those obtained internal-standard Validity for practical various kinds such as engine, machine cooking oils. It found that is effective...

The two methods, which enable us to observe changes in concentration of heavy elements living plants and perform quantitative analysis all heavier than aluminum in-air PIXE with detectors, simultaneously, were successfully applied studies on movement light plants. It was found that including silicone, phosphorus sulfur leaves can be quantitatively analyzed. Accuracy the method for could confirmed by comparing results those obtained an internal-standard method. also elemental elapsed time...

Mohs paste is an external preparation containing zinc hydrochloride and oxide starch as the main ingredient, it used for palliative treatment of patients with surgically untreatable malignant tumors. However, has problems, such changes in hardness viscoelasticity time liquefaction by exudate. To overcome these we modified formulation excluding starch, which cause physical changes, investigated base. In using macrogol ointment base, no marked change was noted hardness, malleability, or...

ABSTRACT A paste comprising fine alumina particles was applied on surfaces of steel plate specimens and a welded joint specimen, the effects restraint visual detection fatigue crack growth were experimentally investigated by performing tests with in situ observations c harge oupled d evice (CCD) microscope through various kinds fractographic elemental analyses using an scanning electron (SEM) probe microanalyser (EPMA). As result, rate specimen drastically retarded wedge effect particles,...