A5008805365- Cancer Diagnosis and Treatment
- Advanced Breast Cancer Therapies
- Economic and Financial Impacts of Cancer
- COVID-19 and healthcare impacts
- Neutropenia and Cancer Infections
- Complement system in diseases
- Cancer Risks and Factors
- Adenosine and Purinergic Signaling
- PI3K/AKT/mTOR signaling in cancer
- Renal and related cancers
- Head and Neck Surgical Oncology
- Breast Cancer Treatment Studies
- Chronic Myeloid Leukemia Treatments
- Bone health and treatments
- Lung Cancer Research Studies
- Fungal Infections and Studies
- Surgical site infection prevention
- Chronic Lymphocytic Leukemia Research
- Streptococcal Infections and Treatments
- Intestinal and Peritoneal Adhesions
- Cancer-related Molecular Pathways
- Neuroblastoma Research and Treatments
- Antifungal resistance and susceptibility
- Chemotherapy-related skin toxicity
- Sarcoma Diagnosis and Treatment
Case Western Reserve University
2022-2024
University Hospitals of Cleveland
2022
University of Rochester
2019-2021
University of Rochester Medical Center
2021
Washington Hospital Healthcare System
2021
Guthrie Robert Packer Hospital
2021
SUNY Upstate Medical University
2021
Hillcrest Hospital
2021
Summa Health System
2017
Northeast Ohio Medical University
2015
Clostridium difficile infection (CDI) has recently markedly increased, incurring greater health care-associated costs and hospitalizations especially in vitamin D deficient patients. Accordingly, the aim of this study was to evaluate relationship between low levels severity recurrence CDI.A retrospective case-control evaluated patients hospitalized 2007 2013 with CDI a positive C. toxin assay. Severe complicated defined based on (1) laboratory or radiological criteria correlated clinically...
Abstract Introduction Cutaneous adverse events related to immune checkpoint inhibitors (ICI) are common and most mild. However, numerous case reports have documented severe ICI-related skin-toxicities such as Stevens-Johnsons Syndrome (SJS) commonly among patients with melanoma lung cancer immunotherapy has now become a mainstay of treatment in these tumors. The use ICIs breast only recently standard care for metastatic high risk early-stage triple negative the publication two landmark...
Neuroendocrine tumors (NETs) are a relatively rare entity; however, the incidence and prevalence of these increasing, likely attributed to improved diagnostic accuracy. The diagnosis suspected NETs is facilitated by clinical symptoms, laboratory test abnormalities such as elevated chromogranin-A, other modalities use computed tomography scans, magnetic resonance imaging positron emission (PET) biopsy. expression high levels somatostatin receptors in enables specialized PET scan using...
In Brief Introduction Primary peritonitis (PP) is occurring in patients without underlying causes such as perforated viscus, preexisting ascites, or nephrosis. We report 2 cases of primary Streptococcus pyogenes and review the literature on this subject since January 1, 2000. Case Reports Patient 1 was a 45-year-old woman who presented to hospital with fever, diarrhea, abdominal pain. Examination revealed hypotension, epigastric tenderness, guarding. Computed tomography (CT) scan negative...
12 Background: Inpatient mortality, defined as death within 30 days of an acute hospital admission, is often used a quality benchmark for healthcare institutions and important metric evaluating care patients with advanced malignancies. In this study we aimed to utilize QOPI performance data identify areas weakness in our practice that may contribute inpatient mortality. Methods: We analyzed 11 EOL measures the database which collected between 2015 2018. These included all related hospice...
We report a case of 37-year-old woman who developed duodenal ulcer while receiving adjuvant neratinib for HER2 positive breast cancer. The clinical course abdominal pain was strongly correlated with the use neratinib. An esophagogastroduodenoscopy (EGD) performed and confirmed diagnosis large ulcer. Neratinib stopped, patient treated proton pump inhibitor. Repeat EGD 3 months later showed complete resolution Given this unexpected serious adverse event only modest benefit in setting, decision...
Abstract Background: Palbociclib (palbo), a CDK4/6 inhibitor, is commonly added to an aromatase inhibitor (AI) as the first line therapy in managing estrogen receptor positive, HER2 non amplified (ER+ HER2-) metastatic breast cancer (MBC). Though more tolerable than chemotherapy, palbo may need dose interruption, delay or reduction due toxicities like neutropenia. Currently, there are no clinical data on effect of relative intensity (RDI) setting outcomes. The primary objective this study...
191 Background: Delivering care for vulnerable cancer patients during a pandemic is challenging given the competing risks of death from versus high case fatality rates SARS-COV-2 (CV-19). Data currently available suggests total rate close to 30%-50% with CV-19 in active malignancy patients. In addition adapting guidelines national organizations reduce social footprint order minimize risk exposure CV-19, our center implemented an isolated clinic personal protective equipment (PPE) and direct...
Hypoglossal nerve palsy is a rare disorder resulting in dysarthria and tongue weakness, usually caused by direct compression or injury. Malignant invasion of the skull base can rarely lead to bilateral hypoglossal at exit canals. We report case 40-year-old man with stage IV colorectal cancer who presented weakness dysphagia was discovered have new metastases his
Delivering care for immunocompromised, high-risk patients with cancer during a pandemic has proven challenging. Patients on chemotherapy have high risk of mortality if contracted COVID-19. If patient goes directly to the emergency room, multiple contact points other individuals can lead unnecessary exposures from any airborne virus, such as Our center implemented an isolated clinic personal protective equipment and direct access COVID-19 rule-out floor manage those febrile neutropenia...