A5087264857- Constructed Wetlands for Wastewater Treatment
- Head and Neck Cancer Studies
- Vestibular and auditory disorders
- Head and Neck Surgical Oncology
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Tracheal and airway disorders
- Urban Stormwater Management Solutions
- Cancer Diagnosis and Treatment
- Phosphorus and nutrient management
- Ear Surgery and Otitis Media
- Salivary Gland Tumors Diagnosis and Treatment
- Microscopic Colitis
- Hearing, Cochlea, Tinnitus, Genetics
- Inflammatory Bowel Disease
- Meningioma and schwannoma management
- Complement system in diseases
- Facial Nerve Paralysis Treatment and Research
- Psoriasis: Treatment and Pathogenesis
- Wastewater Treatment and Reuse
- Lung Cancer Treatments and Mutations
- Coastal wetland ecosystem dynamics
- Respiratory and Cough-Related Research
- Hearing Loss and Rehabilitation
- Sinusitis and nasal conditions
- Voice and Speech Disorders
Universitätsklinik für Hals-, Nasen- und Ohrenheilkunde
2023
University Hospital Leipzig
2023
Boehringer Ingelheim (Germany)
2012-2022
Thüringer Aufbaubank
2022
Helios Klinikum Erfurt
2011-2021
Helios Kliniken
2004-2018
National Jewish Health
2015
Medical University of South Carolina
2015
University of Colorado Denver
2015
Boehringer Ingelheim (Egypt)
2012-2013
The human complement regulator CD55 is a key molecule protecting self-cells from complement-mediated lysis. X-ray diffraction and analytical ultracentrifugation data reveal rod-like arrangement of four short consensus repeat (SCR) domains in both the crystal solution. stalk linking SCR to glycosylphosphatidylinositol anchor extended by addition 11 highly charged O-glycans positions an estimated 177 A above membrane. Mutation mapping hydrophobic potential analysis suggest that interaction...
BackgroundThe German multicenter randomized phase II larynx organ preservation (LOP) trial DeLOS-II was carried out to prove the hypothesis that cetuximab (E) added induction chemotherapy (IC) and radiotherapy improves laryngectomy-free survival (LFS; with preserved larynx) in locally advanced laryngeal/hypopharyngeal cancer (LHSCC).Patients methodsTreatment-naïve patients stage III/IV LHSCC amenable total laryngectomy (TL) were three cycles IC TPF [docetaxel (T) cisplatin (P) 75 mg/m2/day...
Combined sewer systems are designed to transport stormwater surface run off in addition the dry weather flows up defined limits. In most European countries, hydraulic loads greater than design flow discharged directly into receiving water bodies, with minimal treatment (screening, sedimentation), or no at all. One feasible solution prevent waters from strong negative impacts seems be application of vertical constructed wetlands. Germany, first attempts use this ecological technology were...
The St George's Respiratory Questionnaire (SGRQ) has been used to measure health-related quality of life (HRQoL) in patients with idiopathic pulmonary fibrosis (IPF). This analysis evaluated the psychometric properties SGRQ using data from 428 IPF who participated a 12-month, randomised, placebo-controlled phase II trial nintedanib. Internal consistency (Cronbach's α) was 0.91 for total and >0.70 domain scores. Test–retest reliability (intraclass correlation coefficients) 0.77, 0.69 0.66...
Introduction We evaluated the psychometric properties of St George’s Respiratory Questionnaire (SGRQ) in patients with idiopathic pulmonary fibrosis (IPF) using data from two INPULSIS trials. Methods Data 1061 treated nintedanib or placebo were pooled. Internal consistency, test–retest reliability, construct validity, known-groups responsiveness and responder thresholds examined. Results Cronbach’s α was 0.93 for SGRQ total score >0.75 domain scores. In stable disease based on change...
Abstract To examine the impact of comorbidity on overall survival ( OS ) in a population‐based study patients with head and neck cancer who were treated between 2009 2011. Data 1094 primary carcinomas without distant metastasis from Thuringian registries evaluated concerning influence patient's characteristics . prior to diagnosis was adapted Charlson Comorbidity CCI ), age‐adjusted ACCI HNCCI simplified score SCS Adult Evaluation–27 ACE ‐27). Most male (80%; median age: 60 years; 50% stage...
The French Outermost Regions are under tropical climate yet still have to comply with both and EU regulations. vertical-flow constructed wetland systems appear well adapted the technical specifics of these regions but their adaptation requires new design guidelines be defined (area needed, number filters, type plants, material used, etc.). A study was started in 2008, backing from national water authorities, implement full-scale experimental sites assess impacts local context on...