A5102008167- Wildlife Ecology and Conservation
- Signaling Pathways in Disease
- Ecology and Vegetation Dynamics Studies
- Protein Tyrosine Phosphatases
- Musculoskeletal pain and rehabilitation
- Neurobiology and Insect Physiology Research
- Animal Ecology and Behavior Studies
- Bone Tissue Engineering Materials
- Shoulder Injury and Treatment
- Tissue Engineering and Regenerative Medicine
- IoT Networks and Protocols
- Genetics, Aging, and Longevity in Model Organisms
- Analog and Mixed-Signal Circuit Design
- Bacterial Genetics and Biotechnology
- Spine and Intervertebral Disc Pathology
- FOXO transcription factor regulation
- IoT and Edge/Fog Computing
- Viral Infections and Outbreaks Research
- ECG Monitoring and Analysis
- Viral Infections and Vectors
- Medical Imaging and Analysis
- Genomics and Phylogenetic Studies
- Advanced Memory and Neural Computing
- Digital Filter Design and Implementation
- RNA and protein synthesis mechanisms
Universidad Publica de Navarra
2024
Navarrabiomed
2024
Universidad de Málaga
2022
University of Buenos Aires
2011-2020
Universidad San Pablo
2020
Consejo Nacional de Investigaciones Científicas y Técnicas
2014-2020
University of Chile
2017
University of Mary
2016
Fundación Ciencias Exactas y Naturales
2012
Pontificia Universidad Católica de Chile
2005
Significance AAA+ proteases are ring-shaped machines with a central narrow pore used to translocate protein substrates into proteolytic chamber. Knotted proteins, however, may block the by formation of an incompressible tight knot. Here, we determined how archetypal ClpXP protease degrades substrate containing trefoil A knot is degraded quickly but not when it fused GFP placed downstream Specifically, releases partially products buttressed against GFP. Furthermore, degradation harboring...
Abstract Bacteria synchronize the expression of genes with related functions by organizing into operons so that they are cotranscribed together in a single polycistronic messenger RNA. However, some cellular processes may benefit if simultaneous production operon proteins coincides inhibition an antagonist gene. To coordinate such situations, bacteria have evolved noncontiguous (NcOs), subtype contain one or more transcribed opposite direction to other genes. This structure results...
Summary In this study, we identified hantavirus genotypes and their reservoirs evaluated the spatial temporal distribution of virus in rodent population three protected areas Argentina over 3 years (2007–2010). A total 837 rodents were captured with an effort 22 117 trap‐nights. We detected genotype Lechiguanas Oligoryzomys nigripes O. flavescens Pergamino Akodon azarae . There was no correlation between seroprevalence trap success host. The proportion seropositive males significantly higher...
Habitat use of rodents is associated to environmental variables, species requirements and biological interactions. The aim this study was analyse the macro microhabitat spatial variation in abundance small sylvan that inhabit Otamendi Natural Reserve, Argentina. We studied rodent communities six habitats: riparian forest, Celtis tala lowland grassland, salt marsh two highland grasslands. captured a total 153 individual Scapteromys aquaticus Thomas 1920, Akodon azarae Fischer 1829,...
In contrast to trials of training without intervals (massed training), spaced over time (spaced training) induce a more persistent memory identified as long-term (LTM). This phenomenon, known the spacing effect for memory, is poorly understood. LTM supported by structural synaptic plasticity; however, how synapses integrate stimuli remains elusive. Here, we analyzed events plasticity at single-synapse level after distinct patterns stimulation in motoneurons Drosophila . We found that...
Noonan syndrome and related disorders are caused by mutations in genes encoding for proteins of the RAS-ERK1/2 signaling pathway, which affect development enhanced ERK1/2 activity. However, mutations' effects throughout adult life unclear. In this study, we identify that protein most commonly affected syndrome, phosphatase SHP2, known Drosophila as corkscrew (CSW), controls span, triglyceride levels, metabolism without affecting ERK pathway. We found CSW loss-of-function extended span...
Abstract Extracellular matrix (ECM) deposition in demyelinating multiple sclerosis (MS) lesions may impede axonal regeneration and modify immune responses. RGC-32 plays an important role mediation of TGF-β downstream effects, but its ECM gliosis has not been investigated. To gain more insight into the played by gliosis, we examined production reactive astrocyte marker α-smooth muscle actin (α-SMA) expression. In MS lesions, collagen I, IV V were found to be expressed astrocytes which also...
This work proposes lossless and near-lossless compression algorithms for multi-channel biomedical signals. The are sequential efficient, which makes them suitable low-latency low-power signal transmission applications. We make use of information theory processing tools (such as universal coding, prediction, fast online implementations multivariate recursive least squares), combined with simple methods to exploit spatial well temporal redundancies typically present in tested publicly...