A5045264397- Liver Disease and Transplantation
- Bone health and osteoporosis research
- Liver Disease Diagnosis and Treatment
- Dermatology and Skin Diseases
- Bone and Joint Diseases
- Organ Transplantation Techniques and Outcomes
- Foot and Ankle Surgery
- Medical Imaging Techniques and Applications
- Bone health and treatments
- Adrenal Hormones and Disorders
- Urticaria and Related Conditions
- Advanced Radiotherapy Techniques
- Contact Dermatitis and Allergies
- Abdominal Trauma and Injuries
- Food Allergy and Anaphylaxis Research
- Scoliosis diagnosis and treatment
- Fungal Infections and Studies
- Cytomegalovirus and herpesvirus research
- Allergic Rhinitis and Sensitization
- Diabetic Foot Ulcer Assessment and Management
- Viral Infections and Immunology Research
- Antifungal resistance and susceptibility
- Transplantation: Methods and Outcomes
- Radiation Dose and Imaging
- Breast Implant and Reconstruction
Imperial College Healthcare NHS Trust
2024
Hammersmith Hospital
2024
University of Southern California
2023
Mater Misericordiae University Hospital
2021-2023
Children's Hospital of Los Angeles
2019-2021
New York Proton Center
2020
St. James's Hospital
2010-2018
Trinity College Dublin
2016
University College Dublin
2013-2014
St. Vincent's University Hospital
2013-2014
Myeloid differentiation factor (MyD)-88 is a key adaptor protein that plays major role in the innate immune pathway. How MyD88 may regulate host response inflammatory heart disease unknown.We found cardiac level of was significantly increased hearts wild-type mice after exposure to Coxsackievirus B3 (CVB3). MyD88(-/-) showed dramatic higher survival rate (86%) contrast low (35%) MyD88(+/+) CVB3 infection (P<0.0001). Pathological examination significant decrease and pancreatic inflammation...
Biliary obstruction can be due to both malignant and benign pancreaticobiliary disease. Currently, there are no biomarkers that accurately help make this distinction. MicroRNAs (miRNAs) stable molecules in tissue biofluids commonly deregulated cancer. The MIRABILE study aimed identify miRNAs bile differentiate from
Thrombocytopenia affects patients undergoing liver transplantation. Intraoperative platelet transfusion has been shown to independently influence survival after transplantation at 1 and 5 years. We examined the impact of thrombocytopenia intraoperative on short-term graft overall orthotopic (OLT). A total 399 first OLT were studied. Graft in with different degrees or without described. The degree prior did not affect transplant. However, receiving platelets was significantly reduced year ( P...
Spleen stiffness can be measured by transient elastography. Recent studies have shown that spleen correlates with hepatic venous pressure gradient and predict oesophageal varices. Elevated in cirrhosis has been attributed to splenic tissue hyperplasia fibrosis, portal hypertension its consequent hyperdynamic circulation. The aim of this study was investigate changes after orthotopic liver transplantation (OLT) when resolves.Twenty-one patients awaiting OLT were studied prospectively, while...
Drug concentrations in cerebrospinal fluid have been assumed to be a natural surrogate for total drug exposures the central nervous system. The present communication reports data set from study of 30 compounds mice. An attempt was made correlate and unbound plasma via incorporation vitro P-glycoprotein (Pgp)-mediated transport data.Pgp-deficient (Pgp –/–) wild-type mice were dosed with interest by oral gavage (orally) at 5 mg kg−1. Plasma samples collected 1 h post-dosing, analysed liquid...
Summary Influenza virus infection is now recognised as a risk factor for invasive pulmonary aspergillosis ( IPA ). Delays in diagnosis contribute to delayed commencement of antifungal therapy. In addition, the emergence resistance first‐line triazole agents puts emphasis on early detection prevent adverse outcomes. We present 2 allogeneic stem cell transplant patients who developed due triazole‐resistant Aspergillus fumigatus following influenza infection. underline challenges faced...
Avascular necrosis (avn) of the hip is a well-documented side effect corticosteroid therapy, but it has also been described as complication radiation and chemotherapy. Many prostate cancer patients undergo treatment with all three those therapeutic modalities, yet reported cases avn in are rare. Symptoms that might potentially alert physicians to this nonspecific may be attributed progression, particular progressive bone metastasis.Here, we report on 79-year-old man diagnosed...
Allergic contact dermatitis (ACD) to nickel in wristwatches has been documented since the 1930s.1 We report a case of ACD an Apple Watch, popular modern timepiece. A 34-year-old woman with allergic rhinitis was referred for patch testing 6 months pruritic rashes on hands and left wrist. On wrist, she had previously worn Watch Series 2 without associated skin issues; after upgrading 5, within several weeks developed persistent rash directly beneath watch face. Other than corticosteroid simple...
A 60-year-old woman with breast cancer metastatic to the bones experienced no adverse skin reaction at lumbar spine after a single 8-Gy photon-beam fraction prescribed depth of 5 cm. However, subsequent treatment thoracic using same dose, fractionation, and technique resulted in erythema permanent hyperpigmentation. After careful investigation, differences were identified her concurrent use possibly radiosensitizing medications during various radiotherapy treatments nor possible errors...
Abstract Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare, aggressive hematologic malignancy that can present with multiorgan involvement including the skin. While this entity accounts for 0.1% of all cutaneous lymphomas in adults, fewer than 90 pediatric cases have been described literature. We three BPDCN, highlighting variable and clinical presentation.
Fazit In dieser Studie konnte gezeigt werden, dass die Magnetresonanz-Technik mit QSM eine sensitive Methode zur Quantifizierung des Eisengehalts im Gehirn darstellt. Bei Patienten ß-Thalassämia major zeigte sich verstärkte Eisenablagerung Gehirn, wobei der ermittelte Eisengehalt in unterschiedlichen Hirnregionen einem weiten Bereich variierte, so Autoren.