A5047620893- Synthesis and biological activity
- Multicomponent Synthesis of Heterocycles
- Synthesis and Biological Evaluation
- Click Chemistry and Applications
- SARS-CoV-2 and COVID-19 Research
- Biosensors and Analytical Detection
- Synthesis and Characterization of Heterocyclic Compounds
- COVID-19 Clinical Research Studies
- Pharmaceutical studies and practices
- Advanced biosensing and bioanalysis techniques
- Osteoarthritis Treatment and Mechanisms
- SARS-CoV-2 detection and testing
- Molecular spectroscopy and chirality
- Long-Term Effects of COVID-19
- Advanced Chemical Sensor Technologies
- Synthesis of heterocyclic compounds
- Inflammatory Biomarkers in Disease Prognosis
- Nonlinear Dynamics and Pattern Formation
- Synthesis and Reactivity of Sulfur-Containing Compounds
- Identification and Quantification in Food
- Renal cell carcinoma treatment
- Synthesis and bioactivity of alkaloids
- Liquid Crystal Research Advancements
- Advanced Drug Delivery Systems
- Drug Solubulity and Delivery Systems
Ministry of AYUSH
2025
Central Council for Research in Ayurvedic Science
2025
National Institute for Interdisciplinary Science and Technology
2020-2023
Council of Scientific and Industrial Research
2023
Academy of Scientific and Innovative Research
2023
Stable drug-type tablets and capsules are painful to drink or chew for many pediatric geriatric patients. Accurate dosing is also an issue liquid orals (syrup, suspension, emulsion, so on). Several fast-dissolving drug delivery systems have been designed address these issues. One of the innovative methods rapid with self-administration without water chewing a thin polymer oral strip. Strip-forming polymers, plasticizers, active pharmaceutical ingredients, sweetening agents, saliva enhancing...
Paper-based sensors are a new possible technology for fabricating easy, economical, portable, and expendable analytical devices various application fields counting, diagnosis clinically, control of the quality food, environmental monitoring. The distinctive characteristics paper that enable transport passive liquid affinity with chemicals/biochemical is principal lead employing as sensing platform. Even if paper-based extremely favorable, they quite abided due to undeniable constraints,...
A novel series of 1,3-diphenyl-pyrazole-4-carboxylic acid and its thiazole derivatives were conveniently synthesized followed by coupling reaction to investigate their efficiency as α-amylase α-glucosidase inhibiting agents. Initially, pyrazole esters obtained using various benzaldehydes precursor subsequently converted respective acids in tetrahydrofuran solvent medium. All the key intermediates coupled with previously amines yield title compound good yield. The current attempt cultivated...
Two novel series of pyrazole and thiophene-linked quinoline analogues via amide bond were conveniently synthesized characterized by IR, NMR, HRMS analysis. The compounds evaluated for their antimicrobial, anti-inflammatory, anti-leukemic activity. antimicrobial evaluation the target clearly showed that compound 11c has better activity compared to other against tested pathogens. anti-inflammatory assay selected 12c with IC50 value 118.73 µg/ml exhibited significant than standard drug Aspirin...
In the current study, bicyclic 1-(7-methyl-3,5-diphenyl-5H-thiazolo(3,2-α)pyrimidine-6-yl)ethanone (4a-l) derivatives have been designed and conveniently synthesized by one-pot three-component method via cyclocondensation of substituted 4-phenylthiazole-2-amine (1a-c), acetylacetone (2) various aromatic aldehydes (3a-d) in presence p-toluene sulfonic acid (PTSA) under acetonitrile solvent medium. The compounds characterized spectral analysis subjected to docking study against protein DNA...
Abstract Background: The severe acute respiratory syndrome coronavirus 2 steady mutation lead to the desperate search for effective treatment and preventive measures disease-2019 (COVID-19) globally. Ayurveda describes various medications that have been recognized their pharmacological properties, particularly immunomodulation anti-viral properties. Objective: objective of this study was comparative assessment Guduchi Ghana Vati Sudarshana intake prophylaxis COVID-19, with a control arm...
Background: The overall survival rates are below 10% in patients with metastatic renal cell carcinoma (RCC) posing a significant health challenge. There is pressing need for novel and simple predictors of metastasis RCC to aid early detection, thereby having prognostic therapeutic implications. Objectives: To assess the efficacy various inflammatory markers such as neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte (PLR), Systemic Inflammatory Response Index (SIRI), Immune-Inflammatory...
In this paper, we report the synthesis of novel liquid crystals (LCs) based on 5-membered pyrazoline heterocycle. The derivative was carried out by [3 + 2] 1,3-dipolar cycloaddition reaction benzaldehyde phenyl hydrazone (1) with acrylonitrile, mediated chloramine-T as oxidising agent, followed addition hydroxylamine hydrochloride, and subsequently alkylated various alkyl chains to afforded title compounds. LCs properties were investigated using differential scanning calorimetry polarising...
In the present study, we have designed a novel series of pyrazolyl-1,3,4-thiadiazole analogues by accommodating 1,3,4-thiadiazole ring at C – 4 pyrazole with and without an amide linkage; 5-methyl-1,3-diphenyl-N-(5-phenyl-1,3,4-thiadiazol-2-yl)-1H-pyrazole-4-carboxamide 2-(5-methyl-1,3-diphenyl-1H-pyrazol-4-yl)-5-phenyl-1,3,4-thiadiazole respectively. We this class heterocycles keeping wide audience in mind, which augment their scientific knowledge. Newly synthesized compounds were...