Kaoru Honaga

ORCID: 0000-0003-0885-2876
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About
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Research Areas
  • Stroke Rehabilitation and Recovery
  • Transcranial Magnetic Stimulation Studies
  • Botulinum Toxin and Related Neurological Disorders
  • Muscle activation and electromyography studies
  • Balance, Gait, and Falls Prevention
  • Acute Ischemic Stroke Management
  • EEG and Brain-Computer Interfaces
  • Dementia and Cognitive Impairment Research
  • Nutrition and Health in Aging
  • Cerebral Palsy and Movement Disorders
  • Vestibular and auditory disorders
  • Neuroscience and Neural Engineering
  • Advanced Technologies in Various Fields
  • Neurological disorders and treatments
  • Neurological Disorders and Treatments
  • Musculoskeletal pain and rehabilitation
  • Parkinson's Disease Mechanisms and Treatments
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Obstructive Sleep Apnea Research
  • Sleep and related disorders
  • Virtual Reality Applications and Impacts
  • Dysphagia Assessment and Management
  • Cancer Treatment and Pharmacology
  • Optical Imaging and Spectroscopy Techniques
  • Spatial Neglect and Hemispheric Dysfunction

Juntendo University
2021-2025

Hebei Rehabilitation Hospital
2013-2024

Keio University
2007-2024

University of Tsukuba
2022

Keio University Hospital
2015-2017

Shizuoka Cancer Center
2014

Background and objective . We devised a therapeutic approach to facilitate the use of hemiparetic upper extremity (UE) in daily life by combining integrated volitional control electrical stimulation with wrist splint, called hybrid assistive neuromuscular dynamic (HANDS). Methods. Twenty patients chronic stroke (median 17.5 months) had moderate severe UE weakness. Before immediately after completing 3 weeks training 40-minute sessions, 5 days per week over wearing system for 8 hours each...

10.1177/1545968308321777 article EN Neurorehabilitation and neural repair 2008-11-07

Background An artificial intelligence (AI)-integrated electromyography (EMG)-driven robot hand was devised for upper extremity (UE) rehabilitation. This detects patients’ intentions to perform finger extension and flexion based on the EMG activities of 3 forearm muscles. Objective study aimed assess effect this in patients with chronic stroke. Methods a single-blinded, randomized, controlled trial 4-week follow-up period. Twenty were assigned active (n = 11) control 9) groups. Patients group...

10.1177/15459683231166939 article EN Neurorehabilitation and neural repair 2023-04-11

Hybrid assistive neuromuscular dynamic stimulation (HANDS) therapy improved paretic upper extremity motor function in patients with severe to moderate hemiparesis. We hypothesized that brain machine interface (BMI) training would be able increase finger muscle activity enough apply HANDS hemiparesis, whose extensor was absent.The aim of this study assess the efficacy BMI followed by hemiparesis.Twenty-nine chronic stroke who could not extend their fingers were participated study. applied for...

10.3233/rnn-160652 article EN Restorative Neurology and Neuroscience 2016-08-30

Upper extremity rehabilitation in persons with stroke should be dose-dependent and task-oriented. Virtual reality (VR) has the potential to used safely effectively home-based rehabilitation. This study aimed investigate effects of virtual upper chronic stroke. was a single-blind, randomized, controlled trial conducted at two centers. The subjects were 14 outpatients more than 6 months after onset participants randomly divided into groups. intervention group (n = 7) performed home program for...

10.1186/s12984-025-01564-5 article EN cc-by-nc-nd Journal of NeuroEngineering and Rehabilitation 2025-02-03

In post-stroke hemiparesis patients, the skeletal muscle mass decrease rapidly with histological degradation. We investigated effect of nutritional supplementation whey protein and vitamin D on quality, in convalescent rehabilitation patients a randomized, single-blinded, placebo-controlled trial. Fifty were randomly assigned to two groups; HP group received supplemental jelly (100 kcal; 10 g; 20 μg) twice day throughout up 16-week period, control placebo jelly. Cross-sectional area (CSA)...

10.3390/nu14030685 article EN Nutrients 2022-02-06

Gait recovery is one of the primary goals stroke rehabilitation. independence a key functional component independent activities in daily living and social participation. Therefore, early prediction gait essential for Trunk function important gait, balance, lower extremity function. The Impairment Scale (TIS) was developed to assess trunk impairment patients with stroke.To evaluate predictive validity TIS acute stroke.A total 102 participated this study. Every participant assessed using TIS,...

10.1177/17562864221140180 article EN Therapeutic Advances in Neurological Disorders 2022-01-01

Background and purpose: Trunk function plays a key role in performing activities of daily living (ADL) including locomotion sitting. Sitting ADL should be performed as early possible especially during the acute phase stroke rehabilitation. Therefore, this study aimed to assess trunk among patients with using Impairment Scale (TIS) predict its functional outcomes. Methods: Overall, 67 (i.e., within 2 days occurrence stroke) were included. The following clinical assessment items obtained 48 h...

10.3389/fneur.2021.665592 article EN cc-by Frontiers in Neurology 2021-06-17

Brain-machine interface training was developed for upper-extremity rehabilitation patients with severe hemiparesis. Its clinical application, however, has been limited because of its lack feasibility in real-world settings. We a new compact task-specific brain-machine system that enables training, including reach-and-grasp tasks, and studied effectiveness motor paralysis stroke.Prospective beforeâ€"after study.Twenty-six chronic hemiparetic stroke.Participants were trained the to pick up...

10.2340/16501977-2275 article EN cc-by-nc Journal of Rehabilitation Medicine 2017-09-26

Abstract Post-stroke disability affects patients’ lifestyles after discharge, and it is essential to predict functional recovery early in hospitalization allow time for appropriate decisions. Previous studies reported important clinical indicators, but only a few indicators were analyzed due insufficient numbers of cases. Although review articles can exhaustively identify many prognostic factors, remains impossible compare the contribution each predictor. This study aimed determine which...

10.1038/s41598-023-39475-x article EN cc-by Scientific Reports 2023-07-29

Objectives To investigate the construct validity of Trunk Impairment Scale (TIS), which was developed to assess trunk impairment in patients with stroke, Parkinson’s disease (PD). Design This retrospective, cross-sectional study enrolled consecutive PD inpatients. Correlation analysis performed clarify whether TIS assessment related other balance functions, lower extremity muscle strength, or walking ability. Factor see how background factors differ from function, limb and Results Examining...

10.3389/fneur.2023.1303215 article EN cc-by Frontiers in Neurology 2024-01-03

Purpose:We hypothesized that recovery of upper extremity motor function is associated with reduction intracortical inhibition and improved reciprocal inhibition. This study examines the relationships functional in chronic stroke spinal Methods:Participants were 61 patients hemiparetic stroke. The participants applied hybrid assistive neuromuscular dynamic stimulation (HANDS) therapy for 3 weeks. Fugl-Meyer test score (FM) modified Ashworth scale (MAS) assessed before (T0), immediately after...

10.3233/rnn-150547 article EN Restorative Neurology and Neuroscience 2015-11-09

This study investigated the effects of a supervised home-based vestibular rehabilitation program using booklet on gait function and dizziness in patients with chronic peripheral hypofunction.This was non-blinded, randomized, controlled trial. Patients (n=42) hypofunction were randomly divided into group (VR group; n=20) or control (n=22). VR received addition to physician care for 4 weeks. The physical therapist checked home when visited outpatient clinic once week. only during trial period....

10.2490/prm.20230002 article EN Progress in Rehabilitation Medicine 2023-01-01

Stepwise linear regression (SLR) is the most common approach to predicting activities of daily living at discharge with Functional Independence Measure (FIM) in stroke patients, but noisy nonlinear clinical data decrease predictive accuracies SLR. Machine learning gaining attention medical field for such data. Previous studies reported that machine models, tree (RT), ensemble (EL), artificial neural networks (ANNs), support vector (SVR), and Gaussian process (GPR), are robust increase...

10.1371/journal.pone.0286269 article EN cc-by PLoS ONE 2023-05-26

ObjectiveTo determine whether poststroke fatigue at admission is associated with the degree of independence in activities daily living patients stroke discharge from subacute rehabilitation wards.DesignRetrospective cohort study.SettingSubacute hospital.ParticipantsA consecutive sample (N=156) who were admitted to a ward between December 2012 and November 2013 enrolled study.InterventionsNot applicable.Main Outcome MeasuresPoststroke was assessed using Fatigue Severity Scale within 2 weeks...

10.1016/j.apmr.2020.10.117 article EN cc-by-nc-nd Archives of Physical Medicine and Rehabilitation 2020-11-05

Abstract Aim To investigate the cognitive function and its relation to home discharge of patients following subacute stroke. Methods This retrospective cohort study included 1,229 convalescent experiencing their first We determined destination demographic clinical information. recorded measurement scores: Mini-Mental State Examination (MMSE) score, Stroke Impairment Assessment Set grip strength, Functional Independence Measure (FIM). performed a multivariable logistic regression analysis...

10.1186/s12883-022-02745-8 article EN cc-by BMC Neurology 2022-06-13

Recently, surface electroencephalogram (EEG)-based brain-machine interfaces (BMI) have been used for people with disabilities. As a BMI signal source, event-related desynchronization of alpha-band EEG (8-13 Hz) during motor imagery (mu ERD), which is interpreted as desynchronized activities the activated neurons, commonly used. However, it often difficult patients severe hemiparesis to produce mu ERD sufficient strength activate BMI. Therefore, whether possible modulate anodal transcranial...

10.2302/kjm.60.114 article EN The Keio Journal of Medicine 2011-01-01

Background:Reciprocal inhibition (RI) may be important for recovering locomotion after stroke. Patterned electrical stimulation (PES) can modulate RI in a manner that could enhanced by voluntary muscle contraction (VC). Objective:To investigate whether VC enhances the PES-induced spinal pa tients with Methods:Twelve patients chronic stroke underwent three 20 min tasks, each on different days: (1) PES (10 pulses, 100 Hz every 2 s) applied to common peroneal nerve; (2) consisting of isometric...

10.3233/rnn-170759 article EN Restorative Neurology and Neuroscience 2018-02-08

A knee-ankle-foot orthosis (KAFO) prevents knee buckling during walking and enables gait training for acute hemiplegic stroke patients with severe disturbances. Although the goal of a KAFO is to improve ability, that is, acquire an ankle-foot (AFO), it not clear how contributes improving ability. Therefore, this study aimed investigate relationship between muscle activities improvement ability in disturbance.

10.3389/fneur.2024.1387607 article EN cc-by Frontiers in Neurology 2024-05-07

AbstractPurpose of the study: To evaluate after-effects pedaling on spinal excitability and reciprocal inhibition in patients with post-stroke spastic hemiparesis. Materials methods: Twenty stroke severe hemiparesis participated this study were instructed to perform 7 min active passive a recumbent ergometer at comfortable speed. H reflexes M waves paretic soleus muscles recorded rest before, immediately after 30 pedaling. The Hmax/Mmax ratio recruitment curve measured. Reciprocal was...

10.3109/00207454.2016.1144055 article EN International Journal of Neuroscience 2016-01-20
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