A5019754996- Plant Molecular Biology Research
- Plant nutrient uptake and metabolism
- Photosynthetic Processes and Mechanisms
- Plant Stress Responses and Tolerance
- Plant tissue culture and regeneration
- Plant Genetic and Mutation Studies
- Genetic Associations and Epidemiology
- Seed Germination and Physiology
- Global Cancer Incidence and Screening
- Cancer Genomics and Diagnostics
- Plant Gene Expression Analysis
The Hyve (Netherlands)
2022
Utrecht University
2012-2016
Summary This work investigates the extent of translational regulation during seed germination. The polysome occupancy each gene is determined by genome‐wide profiling total mRNA and polysome‐associated . reveals extensive Arabidopsis thaliana thousands individual s changes to a large germination process. Intriguingly, these are restricted two temporal phases (shifts) germination, hydration Sequence features, such as upstream open reading frame number, transcript length, stability, secondary...
Abstract Objective The coronavirus disease 2019 (COVID-19) pandemic has demonstrated the value of real-world data for public health research. International federated analyses are crucial informing policy makers. Common models (CDMs) critical enabling these studies to be performed efficiently. Our objective was convert UK Biobank, a study 500 000 participants with rich genetic and phenotypic Observational Medical Outcomes Partnership (OMOP) CDM. Materials Methods We converted Biobank OMOP CDM...
Abstract Basic leucine zippers (bZIPs) form a large plant transcription factor family. C and S1 bZIP groups can heterodimerize, fulfilling crucial roles in seed development stress response. sequences also harbor unique regulatory mechanism, termed Sucrose-Induced Repression of Translation (SIRT). The conservation both C/S1 interactions SIRT remains poorly characterized non-model species, leaving their evolutionary origin uncertain limiting crop research. In this work, we explored recently...
Protein synthesis is a highly energy demanding process and regulated according to cellular levels. Light sugar availability affect mRNA translation in plant cells but the specific roles of these factors remain unclear. In this study, sucrose was applied Arabidopsis seedlings kept light or dark, order distinguish effects on transcription translation. These were studied using microarray analysis steady-state bound translating ribosomes. Steady-state levels affected differently by dark general...