Elena Garcia Lara
A5050753930- Cancer Genomics and Diagnostics
- Bioinformatics and Genomic Networks
- Genetics, Bioinformatics, and Biomedical Research
- Biomedical and Engineering Education
- Innovative Microfluidic and Catalytic Techniques Innovation
- Biotechnology and Related Fields
- Epigenetics and DNA Methylation
- Microbial Community Ecology and Physiology
- Single-cell and spatial transcriptomics
- Global Cancer Incidence and Screening
- Genetic Associations and Epidemiology
- Genomics and Rare Diseases
- Metabolomics and Mass Spectrometry Studies
- Gut microbiota and health
- Ferroptosis and cancer prognosis
The Hyve (Netherlands)
2022-2023
Vrije Universiteit Amsterdam
2021
Abstract International cancer registries make real-world genomic and clinical data available, but their joint analysis remains a challenge. AACR Project GENIE, an international registry collecting from 19 centers, makes >130,000 patients publicly available through the cBioPortal for Cancer Genomics (https://genie.cbioportal.org). For 25,000 patients, additional longitudinal data, including treatment outcome are being collected by GENIE Biopharma Collaborative using PRISSMM curation...
Abstract Objective The coronavirus disease 2019 (COVID-19) pandemic has demonstrated the value of real-world data for public health research. International federated analyses are crucial informing policy makers. Common models (CDMs) critical enabling these studies to be performed efficiently. Our objective was convert UK Biobank, a study 500 000 participants with rich genetic and phenotypic Observational Medical Outcomes Partnership (OMOP) CDM. Materials Methods We converted Biobank OMOP CDM...
The behaviour of microbial communities depends on environmental factors and the interactions community members. This is also case for urinary tract infection (UTI) communities. Here, we devise a computational approach that uses indices complementarity competition based metabolic gene annotation to rapidly predict putative between pair organisms with aim explain pairwise growth effects. We apply our method 66 genomes selected from online databases, which belong 6 genera representing members...
Abstract cBioPortal for Cancer Genomics is an open-source platform interactive, exploratory analysis of large-scale clinico-genomic data sets. provides a suite user-friendly visualizations and analyses, including OncoPrints, mutation “lollipop” plots, variant interpretation, group comparison, survival analysis, expression correlation alteration enrichment cohort patient-level visualization. The public site (https://www.cbioportal.org) accessed by >35,000 unique visitors each month...
<p>List of AACR Project GENIE Consortium Members</p>
<p>List of AACR Project GENIE BPC Core Team Members</p>
<p>List of AACR Project GENIE BPC Core Team Members</p>
<div>Abstract<p>International cancer registries make real-world genomic and clinical data available, but their joint analysis remains a challenge. AACR Project GENIE, an international registry collecting from 19 centers, makes >130,000 patients publicly available through the cBioPortal for Cancer Genomics (<a href="https://genie.cbioportal.org" target="_blank">https://genie.cbioportal.org</a>). For 25,000 patients, additional longitudinal data, including treatment...
<p>List of AACR Project GENIE Consortium Members</p>
<div>Abstract<p>International cancer registries make real-world genomic and clinical data available, but their joint analysis remains a challenge. AACR Project GENIE, an international registry collecting from 19 centers, makes >130,000 patients publicly available through the cBioPortal for Cancer Genomics (<a href="https://genie.cbioportal.org" target="_blank">https://genie.cbioportal.org</a>). For 25,000 patients, additional longitudinal data, including treatment...
Abstract cBioPortal for Cancer Genomics is an open-source platform interactive, exploratory analysis of large-scale cancer genomics data sets. provides a user-friendly interface that integrates genomic and clinical data, suite visualizations analyses, including OncoPrints, mutation “lollipop” plots, variant interpretation, group comparison, survival analysis, expression correlation alteration enrichment cohort patient-level visualization. also external tools CIViC, Digital Slide Archive,...