A5030613870- Toxic Organic Pollutants Impact
- Marine animal studies overview
- Microplastics and Plastic Pollution
- Per- and polyfluoroalkyl substances research
- Effects and risks of endocrine disrupting chemicals
- RNA Interference and Gene Delivery
- Hepatitis B Virus Studies
- Marine Biology and Environmental Chemistry
- Mercury impact and mitigation studies
- Environmental DNA in Biodiversity Studies
- Isotope Analysis in Ecology
- Immune Cell Function and Interaction
- Environmental Toxicology and Ecotoxicology
- Wound Healing and Treatments
- Mesenchymal stem cell research
- Retinal Development and Disorders
- Viral gastroenteritis research and epidemiology
- Microbial Community Ecology and Physiology
- Diabetic Foot Ulcer Assessment and Management
- Developmental Biology and Gene Regulation
- Pharmaceutical and Antibiotic Environmental Impacts
- Neurobiology and Insect Physiology Research
- Glycosylation and Glycoproteins Research
- Monoclonal and Polyclonal Antibodies Research
- Adenosine and Purinergic Signaling
Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou)
2020-2025
Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai)
2020-2025
First Affiliated Hospital of Anhui Medical University
2021
Anhui Medical University
2021
Sun Yat-sen University
2005-2007
Despite the increasing health risks shown by continuous detection of organophosphate esters (OPEs) in biota recent years, information on occurrence and potential OPEs marine mammals remains limited. This study conducted first investigation into body burdens 10 traditional (tOPEs) five emerging (eOPEs) cetacean species (n = 84) from northern South China Sea (NSCS) during 2005–2021. All OPEs, except for 2-ethylhexyl diphenyl phosphate (EHDPHP), were detected these cetaceans, indicating their...
The generation of diverse neuronal types and subtypes from multipotent progenitors during development is crucial for assembling functional neural circuits in the adult central nervous system. During mouse retinogenesis, early retinal give rise to several cell types, including ganglion, amacrine, horizontal, cone, rod cells. It unknown at present how each these fates selected multiple available progenitor. By using a combination bioinformatic, genetic, biochemical approaches, we investigated...
Abstract Programmed cell death 1 (PD-1) monoclonal antibodies have been approved by regulatory agencies for the treatment of various types cancer, and mechanism involves restoration T functions. We report herein X-ray crystal structure a fully human antibody mAb059c fragment antigen-binding (Fab) in complex with PD-1 extracellular domain (ECD) at resolution 1.70 Å. Structural analysis indicates 1) an epitope, comprising fragments from C’D, BC FG loops PD-1, contributes to interaction, 2)...