Shangyi Wu

ORCID: 0000-0003-0910-6170
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About
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Research Areas
  • Biosensors and Analytical Detection
  • Infant Nutrition and Health
  • Advanced biosensing and bioanalysis techniques
  • Bacteriophages and microbial interactions
  • Glycosylation and Glycoproteins Research
  • Gut microbiota and health
  • Neuroendocrine regulation and behavior
  • CRISPR and Genetic Engineering
  • SARS-CoV-2 detection and testing
  • Tryptophan and brain disorders
  • Microfluidic and Bio-sensing Technologies
  • RNA Interference and Gene Delivery
  • Virus-based gene therapy research
  • Pancreatic function and diabetes
  • Animal Genetics and Reproduction

Shenyang Agricultural University
2017-2023

Ministry of Agriculture and Rural Affairs
2022-2023

China Agricultural University
2022-2023

Milk fat globule membrane (MFGM) proteins have recently gained increasing attention, due to their significant biological function. However, the glycosylation of in human MFGM during lactation has not been studied detail. In this study, through mass spectroscopy-based N-glycoproteomics, we analyzed protein MFGM. A total 912 N-glycosylation sites on 506 N-glycoproteins were identified colostrum and mature milk Among them, 220 with 304 differentially expressed Gene Ontology (GO) analysis...

10.1039/c7fo01796k article EN Food & Function 2017-12-29

Comparison of MFGM <italic>N</italic>-glycoproteomes among human and bovine colostrum mature milk reveals diverse compositions biological functions them.

10.1039/c9fo00686a article EN Food & Function 2019-01-01

This study reported an automatic centrifugal system for rapid detection of foodborne pathogenic bacteria based on immunomagnetic separation (IMS) target enrichment and recombinase aided amplification (RAA) nucleic acid detection.

10.1039/d2lc00650b article EN Lab on a Chip 2022-01-01

Background: Foodborne pathogenic bacteria threaten worldwide public health, and simple bacterial detection methods are in urgent need. Here, we established a lab-on-a-tube biosensor for simple, rapid, sensitive, specific of foodborne bacteria. Methods: A rotatable Halbach cylinder magnet an iron wire netting with magnetic silica beads (MSBs) were used effective extraction purification DNA from the target bacteria, recombinase-aided amplification (RAA) was combined clustered regularly...

10.3390/mi14040830 article EN cc-by Micromachines 2023-04-09

The marine horseshoe crab ( Tachypleus tridentatus ) has been considered as food and traditional medicine for many years. Kynurenic acid (KA) was isolated from in this study the first time world. A previous 2018 reported that intraperitoneal administration of KA prevented high‐fat diet‐ (HFD‐) induced body weight gain. Now, we investigated effects intragastric gavage on HFD mice found (5 mg/kg/day) inhibited both gain increase average daily energy intake. reduced serum triglyceride increased...

10.1155/2021/8874503 article EN cc-by Oxidative Medicine and Cellular Longevity 2021-01-01

Foodborne pathogenic bacteria have become a worldwide threat to human health, and rapid sensitive bacterial detection methods are urgently needed. In this study, facile microfluidic chip was developed combined with recombinase-aided amplification (RAA) for of Salmonella typhimurium using non-contact eddy heater dynamic lysis cells 3D-printed fan-shaped active mixer continuous-flow mixing. First, the sample injected into flow through spiral channel coiling around an iron rod under alternating...

10.3390/bios12090726 article EN cc-by Biosensors 2022-09-05
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