A5085952924- Force Microscopy Techniques and Applications
- Microfluidic and Bio-sensing Technologies
- Analytical Chemistry and Sensors
- Lipid Membrane Structure and Behavior
- Advanced Memory and Neural Computing
- Electrochemical Analysis and Applications
- Neuroscience and Neural Engineering
- Ferroelectric and Piezoelectric Materials
- Microbial Fuel Cells and Bioremediation
- Conducting polymers and applications
- Semiconductor materials and devices
- Magnetic and transport properties of perovskites and related materials
- Nanopore and Nanochannel Transport Studies
- Electronic and Structural Properties of Oxides
- Mechanical and Optical Resonators
- Near-Field Optical Microscopy
- Shape Memory Alloy Transformations
- Cell Image Analysis Techniques
- Image Processing Techniques and Applications
- Advanced battery technologies research
- Multiferroics and related materials
- Acoustic Wave Resonator Technologies
- Advanced Electron Microscopy Techniques and Applications
- Molecular Junctions and Nanostructures
- RNA Interference and Gene Delivery
Oak Ridge National Laboratory
2024-2025
Institute for Bioengineering of Catalonia
2016-2024
Universitat de Barcelona
2014-2024
Center for Nanophase Materials Sciences
2024
Barcelona Institute for Science and Technology
2018-2021
Shanghai Institute for Science of Science
2018-2021
Institute of Science and Technology
2019-2020
The elastocaloric alloys Ni-Ti and Cu-Zn-Al in a regenerative refrigeration device can produce outstanding results with up to 20-times larger specific cooling powers compared gadolinium, benchmark magnetocaloric material, comparable coefficient-of-performance (COP) values (≈5). These open new way of making devices more compact systems provide the possibility avoid expensive rare-earth materials. As service our authors readers, this journal provides supporting information supplied by authors....
Abstract Filamentous cable bacteria display long-range electron transport, generating electrical currents over centimeter distances through a highly ordered network of fibers embedded in their cell envelope. The conductivity these periplasmic wires is exceptionally high for biological material, but chemical structure and underlying transport mechanism remain unresolved. Here, we combine high-resolution microscopy, spectroscopy, imaging on individual bacterium filaments to demonstrate that...
We report on compressive strain measurements in polycrystalline magnetic shape memory alloys aimed at determining the entropy change associated with their elastocaloric effect. It is shown that for a maximum applied stress of 100 MPa, stress-induced amounts to ΔS=21 J/kg K. This value compares well values reported nonmagnetic alloys, and it same order as those best giant magnetocaloric materials moderate fields.
<title>Abstract</title> Biofilms are complex microbial communities critical in medical, industrial, and environmental contexts. Understanding their assembly, structure, genetic regulation, interspecies interactions, responses is key to developing effective control mitigation strategies. While Atomic Force Microscopy (AFM) offers critically important high-resolution insights on structural functional properties at the cellular even sub-cellular level, its limited scan range labor-intensive...
Van der Waals layered ferroelectrics, such as CuInP2S6 (CIPS), offer a versatile platform for miniaturization of ferroelectric device technologies. Control the targeted composition and kinetics CIPS synthesis enables formation stable self-assembled heterostructures nonferroelectric In4/3P2S6 (IPS). Here, we use quantitative scanning probe microscopy methods combined with density functional theory (DFT) to explore in detail nanoscale variability dynamic properties CIPS-IPS heterostructure. We...
Abstract Probing nanoscale electrical properties of organic semiconducting materials at the interface with an electrolyte solution under externally applied voltages is key in field bioelectronics. It demonstrated that conductivity and interfacial capacitance active channel electrolyte‐gated field‐effect transistor (EGOFET) operation can be probed using scanning dielectric microscopy force detection mode liquid environment. Local electrostatic versus gate voltage transfer characteristics are...
We show that the internal hydration properties of single Bacillus cereus endospores in air under different relative humidity (RH) conditions can be determined through measurement its electric permittivity by means quantitative electrostatic force microscopy (EFM). an increase RH from 0% to 80% induces a large equivalent homogeneous bacterial endospores, ∼4 up ∼17, accompanied only small endospore height, just few nanometers. These results correlate moisture content with corresponding...
The dielectric constant of flagellin proteins in flagellar bacterial filaments ∼10–20 nm diameter is measured using scanning microscopy.
Mapping the dielectric constant at nanoscale of samples showing a complex topography, such as non-planar nanocomposite materials or single cells, poses formidable challenges to existing microscopy techniques. Here we overcome these limitations by introducing Scanning Dielectric Force Volume Microscopy. This scanning probe technique is based on acquisition electrostatic force approach curves every point sample and its post-processing quantification using computational model that incorporates...
The specific capacitance of ultrathin organic self-assembled monolayers at metal/electrolyte interfaces is measured with nanoscale spatial resolution.
Mapping the biochemical composition of eukaryotic cells without use exogenous labels is a long-sought objective in cell biology. Recently, it has been shown that maps on dry single bacterial with nanoscale spatial resolution can be inferred from quantitative dielectric constant obtained scanning microscope. Here, this approach also applied to much more challenging case fixed and cells, which are highly heterogeneous show micrometric topographic variations. More importantly, demonstrated main...
We analyze the frequency dependence of force between ac-voltage-biased plates in electrolyte solutions. To this end we solve analytically Poisson-Nernst-Planck transport model dilute concentration and low voltage regime for a 1:1 symmetric with blocking electrodes under dc+ac applied voltage. The total force, which is resultant electric osmotic forces, shows complex on plate separation, frequency, ion concentration, compact layer properties, different from that predicted electrostatic...
Abstract Liposomes are widely used as drug delivery carriers and cell model systems. Here, we measure the dielectric properties of individual liposomes adsorbed on a metal electrode by in-liquid scanning microscopy in force detection mode. From measurements lamellarity liposomes, separation between lamellae specific capacitance lipid bilayer can be obtained. As application considered case non-extruded DOPC with radii range ~ 100–800 nm. Uni-, bi- tri-lamellar have been identified, largest...
In this study, we assessed the capacity of a previously reported engineered liposomal formulation, which had been tested against model membranes mimicking lipid composition HeLa plasma membrane, to fuse and function as nanocarrier in cells. We used atomic force microscopy observe physicochemical changes on cell surface confocal determine how liposomes interact with released their load. addition, performed viability assays using methotrexate an active drug obtain proof concept formulation´s...
Abstract Sizing natural or engineered single nanoscale objects is fundamental in many areas of science and technology. To achieve it several advanced microscopic techniques have been developed, mostly based on electron scanning probe microscopies. Still for soft poorly adhered samples the existing face important challenges. Here, we propose an alternative method to size measurement its electric polarization. The Electrostatic Force Microscopy measurements combined with a specifically...
The specific capacitance of biological membranes is a key physical parameter in bioelectricity that also provides valuable physicochemical information on composition, phase, or hydration properties. Cholesterol known to modulate the properties biomembranes, but its effect has not been fully established yet. Here we use high spatial resolution capabilities in-liquid scanning dielectric microscopy force detection mode directly demonstrate DOPC bilayer patches at 50% cholesterol concentration...
Mapping the dielectric properties of cells with nanoscale spatial resolution can be an important tool in nanomedicine and nanotoxicity analysis, which complement structural mechanical measurements. Recently we have shown that constant maps obtained on dried fixed air environment by means scanning force volume microscopy. Here, demonstrate such measurements also performed much more challenging case liquid environment. Performing media contributes to preserve better structure cells, while...
Charge transport in electrolyte-gated organic field-effect transistors (EGOFETs) is governed by the microstructural property of semiconducting thin film that direct contact with electrolyte. Therefore, a comprehensive nanoscale operando characterization active channel crucial to pinpoint various charge bottlenecks for rational and targeted optimization devices. Here, local electrical properties EGOFETs are systematically probed in-liquid scanning dielectric microscopy (in-liquid SDM) picture...
Abstract Filamentous cable bacteria display unrivalled long-range electron transport, generating electrical currents over centimeter distances through a highly ordered network of fibers embedded in their cell envelope. The conductivity these periplasmic wires is exceptionally high for biological material, but chemical structure and underlying transport mechanism remain unresolved. Here, we combine high-resolution microscopy, spectroscopy, imaging on individual bacterium filaments to...
Shewanella oneidensis MR-1 is a metal-reducing bacterium that able to exchange electrons with solid-phase minerals outside the cell. These bacterial cells can produce outer membrane extensions (OMEs) are tens of nanometers wide and several microns long. The capability these OMEs transport currently under investigation. Tubular chemically fixed from S. have shown good dc conducting properties when measured in an air environment. However, no direct demonstration conductivity more common...
Abstract Electrolyte‐gated organic transistors (EGOTs) leveraging semiconductors' electronic and ionic transport characteristics are the key enablers for many biosensing bioelectronic applications that can selectively sense, record, monitor different biological biochemical processes at nanoscale translate them into macroscopic electrical signals. Understanding such transduction mechanisms requires multiscale characterization tools to comprehensively probe local properties link with device...